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8 research outcomes, page 1 of 1
  • publication . Article . 2018
    Open Access English
    Authors:
    Dixon-Suen, Suzanne C.; Nagle, Christina M.; Thrift, Aaron P.; Pharoah, Paul D. P.; Ewing, Ailith; Pearce, Celeste Leigh; Zheng, Wei; Chenevix-Trench, Georgia; Fasching, Peter A.; Beckmann, Matthias W.; ...
    Publisher: Nature Publishing Group UK
    Project: NIH | USC CANCER CENTER EPIDEMI... (2P01CA017054-17), NIH | HEREDITARY BREAST CANCER-... (5R01CA058860-02), NIH | Ovarian Cancer and Gonado... (5R03CA115195-02), NIH | ROSWELL PARK MEMORIAL INS... (5P30CA016056-17), NIH | Phytoestrogens, alcohol, ... (1K07CA095666-01A1), NIH | PRE SURGICAL O6 BENZYLGUA... (3M01RR000056-38S3), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN067010-000), NIH | MOUSE GENETICS (2P30CA008748-43), NHMRC | Generating the evidence t... (1073898), EC | COGS (223175),...

    Background:\ud \ud Observational studies suggest greater height is associated with increased ovarian cancer risk, but cannot exclude bias and/or confounding as explanations for this. Mendelian randomisation (MR) can provide evidence which may be less prone to bias.\ud M...

  • publication . Article . Other literature type . 2016
    Open Access
    Authors:
    Alice Lee; Penelope Webb; Allan Jensen; Signe Marie Jensen; Estrid Høgdall; Susan Ramus; Stacey Winham; Usha Menon; Lambertus Kiemeney;
    Publisher: Elsevier BV
    Project: NIH | Training Grant in Genomic... (5T32ES013678-05), NHMRC | Molecular Epidemiology of... (400281), NIH | Genetic Epidemiology of O... (5K07CA143047-02), NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MOLECULAR EPIDEMIOLOGY OF... (5R01CA076016-04), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN025403-000), NIH | CASE CONTROL STUDY OF OVA... (5R01CA074850-05), NIH | NORTHERN CALIFORNIA COOPE... (5U01CA069417-02), NIH | DNA POLYMORPHISMS IN OVAR... (5R01CA080742-04),...

    PURPOSE: Socioeconomic status (SES) is a known predictor of survival for several cancers and it has been suggested that SES differences affecting tumour stage at diagnosis may be the most important explanatory factor for this. However, only a limited number of studies h...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Luo, Li; Orlow, Irene; Kanetsky, Peter A.; Thomas, Nancy E.; Fang, Shenying; Lee, Jeffrey E.; Berwick, Marianne; Lee, Ji-Hyun;
    Publisher: Public Library of Science
    Project: NIH | CANCER CENTER RESEARCH AD... (5P30CA118100-05), NIH | Solar Exposure and Melano... (1R01CA112524-01), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Epidemiologic Parameters ... (5R01CA098438-03), NIH | Melanoma RAS/BRAF Mutatio... (5R01CA112243-10), NIH | UNC-CH Center for Environ... (5P30ES010126-11), NIH | UT M.D. Anderson Cancer C... (5P50CA093459-03), NIH | CORE--PROTEOMICS (5P30CA016086-33), NIH | A MODEL FOR GENETIC SUSCE... (5U01CA083180-03), NIH | USC COMPREHENSIVE CANCER ... (3P30CA014089-17S1)

    The prognostic improvement attributed to genetic markers over current prognostic system has not been well studied for melanoma. The goal of this study is to evaluate the added prognostic value of Vitamin D Pathway (VitD) SNPs to currently known clinical and demographic ...

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Amos, CI; Dennis, Joe; Wang, Z; Byun, J; Schumacher, FR; Gayther, SA; Casey, G; Hunter, DJ; Sellers, TA; Gruber, SB; ...
    Publisher: American Association for Cancer Research
    Project: NIH | MOLECULAR EPIDEMIOLOGY OF... (5R01CA081488-05), NIH | Discovery Expansion and R... (5U19CA148065-04), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Career Development (Ingle... (5P50CA116201-08), NIH | Breast Cancer Family Regi... (1UM1CA164920-01A1), NIH | Mayo Clinic SPORE in Ovar... (3P50CA136393-05S1), NIH | Follow-up of Ovarian Canc... (3U19CA148112-04S1), NIH | Mayo Comprehensive Cancer... (3P30CA015083-37S2), EC | RADIOGENFF (656144), NIH | Epidemiologic Studies (5U19CA148107-04),...

    Background: Common cancers develop through a multistep process often including inherited susceptibility. Collaboration among multiple institutions, and funding from multiple sources, has allowed the development of an inexpensive genotyping microarray, the OncoArray. The...

  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Emiliano Calvo; Sarina Piha-Paul; Sherene Loi; Victor Moreno;
    Publisher: Springer Science and Business Media LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | ERBB2 TARGETED ANTITUMOR ... (5R01CA080195-04), NIH | Cancer Center Support (CO... (3P30CA016672-41S4), NIH | Understanding Long Tail D... (5R01CA204749-03), NIH | Informatics to enable rou... (5U01CA180964-02), NIH | Cancer Chemotherapy Train... (5T32CA009207-29), NIH | SPORE in Breast Cancer (3P50CA098131-15S1), NIH | Center for Clinical and T... (4UL1TR000371-10), NIH | USC COMPREHENSIVE CANCER ... (3P30CA014089-17S1)

    Somatic mutations of ERBB2 and ERBB3 (which encode HER2 and HER3, respectively) are found in a wide range of cancers. Preclinical modelling suggests that a subset of these mutations lead to constitutive HER2 activation, but most remain biologically uncharacterized. Here...

  • publication . Article . 2016
    Open Access
    Authors:
    Permuth, J. B.; Reid, B.; Earp, M.; Chen, Y. A.; Monteiro, A. N. A.; Chen, Z.; Chenevix-Trench, G.; Fasching, P. A.; Beckmann, M. W.; Lambrechts, D.; ...
    Project: NIH | Epidemiology of Ovarian C... (5R01CA087538-02), NIH | Premenopausal Hormone Lev... (5R01CA067262-08), NIH | MOUSE GENETICS (2P30CA008748-43), NHMRC | Molecular Epidemiology of... (400281), NIH | Genetic Epidemiology of O... (5K07CA143047-02), NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NHMRC | Epidemiology of Chronic D... (209057), NIH | Mayo Clinic SPORE in Ovar... (3P50CA136393-05S1), NHMRC | Towards cancer control: P... (199600), NIH | COLLABORATIVE STUDY OF OV... (5R01CA058598-05),...

    RNA editing in mammals is a form of post-transcriptional modification in which adenosine is converted to inosine by the adenosine deaminases acting on RNA (ADAR) family of enzymes. Based on evidence of altered ADAR expression in epithelial ovarian cancers (EOC), we hypo...

  • publication . Article . 2016
    Open Access English
    Authors:
    Jolanta Lissowska; Sara Olson; Zachary Fogarty; yian Chen; Peter Kraft; Hui-Yi Lin; Alvaro Monteiro; Jeremy Chien; Stacey Winham;
    Publisher: Impact Journals LLC
    Project: CIHR , NIH | USC COMPREHENSIVE CANCER ... (3P30CA014089-17S1), NIH | CASE-CONTROL STUDY OF OVA... (1R01CA061132-01), NIH | Genes, Hormones &Environm... (5R01CA054419-14), NIH | MOLECULAR EPIDEMIOLOGY OF... (5R01CA076016-04), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN025403-000), NIH | Mayo Clinic SPORE in Ovar... (3P50CA136393-05S1), NIH | COLLABORATIVE STUDY OF OV... (5R01CA058598-05), NIH | CANCER CENTER SUPPORT GRA... (3P30CA072720-07S2), NIH | OVARIAN CANCER RISK AND S... (5K07CA080668-06),...

    Background: Genome-wide association studies have identified several common susceptibility alleles for epithelial ovarian cancer (EOC). To further understand EOC susceptibility, we examined previously ungenotyped candidate variants, including uncommon variants and those ...

  • publication . Other literature type . Article . 2016
    Open Access English
    Authors:
    Estrid Høgdall; Allan Jensen; Usha Menon;
    Project: NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN055424-007), NIH | SURVEILLANCE, EPIDEMIOLOG... (N01PC067001-001), NIH | Epidemiology of Ovarian C... (5R01CA087538-02), NIH | Steroid Hormone Genes and... (5R01CA112523-03), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MHC-Restricted and MHC-No... (1P50CA159981-01A1), NIH | Identifying Ovarian Cance... (1R01CA141154-01A2), NIH | The Progesterone Receptor... (1R03CA113148-01), NIH | Genes, Hormones &Environm... (5R01CA054419-14), NIH | University of Michigan Co... (3P30CA046592-20S2),...

    OBJECTIVE: To describe the association between postmenopausal estrogen-only therapy use and risk of ovarian carcinoma, specifically with regard to disease histotype and duration and timing of use. METHODS: We conducted a pooled analysis of 906 women with ovarian carcino...

8 research outcomes, page 1 of 1
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