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5 research outcomes, page 1 of 1
  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Thilo Dörk; Stuart MacGregor; Sara Olson; Anna Jakubowska; Liisa M Pelttari; Susan Ramus; Tomasz Kluz; Ian Campbell; Jolanta Lissowska; Yi Lu; ...
    Publisher: eScholarship, University of California
    Project: NIH | Mayo Clinic SPORE in Ovar... (3P50CA136393-05S1), NHMRC | Towards cancer control: P... (199600), NIH | COLLABORATIVE STUDY OF OV... (5R01CA058598-05), NIH | Steroid Hormone Genes and... (5R01CA112523-03), NIH | Regulatory T Cell Functio... (5R01CA126841-04), NIH | HEREDITARY BREAST CANCER-... (5R01CA058860-02), NIH | Ovarian Cancer and Gonado... (5R03CA115195-02), NIH | Premenopausal Hormone Lev... (5R01CA067262-08), NIH | The Mitochondrial Genome ... (5R01CA149429-05), NIH | MOUSE GENETICS (2P30CA008748-43),...

    BACKGROUND: In vitro and observational epidemiological studies suggest that vitamin D may play a role in cancer prevention. However, the relationship between vitamin D and ovarian cancer is uncertain, with observational studies generating conflicting findings. A potenti...

  • publication . Article . 2018
    Open Access English
    Authors:
    Dixon-Suen, Suzanne C.; Nagle, Christina M.; Thrift, Aaron P.; Pharoah, Paul D. P.; Ewing, Ailith; Pearce, Celeste Leigh; Zheng, Wei; Chenevix-Trench, Georgia; Fasching, Peter A.; Beckmann, Matthias W.; ...
    Publisher: Nature Publishing Group UK
    Project: NIH | USC CANCER CENTER EPIDEMI... (2P01CA017054-17), NIH | HEREDITARY BREAST CANCER-... (5R01CA058860-02), NIH | Ovarian Cancer and Gonado... (5R03CA115195-02), NIH | ROSWELL PARK MEMORIAL INS... (5P30CA016056-17), NIH | Phytoestrogens, alcohol, ... (1K07CA095666-01A1), NIH | PRE SURGICAL O6 BENZYLGUA... (3M01RR000056-38S3), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN067010-000), NIH | MOUSE GENETICS (2P30CA008748-43), NHMRC | Generating the evidence t... (1073898), EC | COGS (223175),...

    Background:\ud \ud Observational studies suggest greater height is associated with increased ovarian cancer risk, but cannot exclude bias and/or confounding as explanations for this. Mendelian randomisation (MR) can provide evidence which may be less prone to bias.\ud M...

  • publication . Article . 2016
    Open Access
    Authors:
    Permuth, J. B.; Reid, B.; Earp, M.; Chen, Y. A.; Monteiro, A. N. A.; Chen, Z.; Chenevix-Trench, G.; Fasching, P. A.; Beckmann, M. W.; Lambrechts, D.; ...
    Project: NIH | Epidemiology of Ovarian C... (5R01CA087538-02), NIH | Premenopausal Hormone Lev... (5R01CA067262-08), NIH | MOUSE GENETICS (2P30CA008748-43), NHMRC | Molecular Epidemiology of... (400281), NIH | Genetic Epidemiology of O... (5K07CA143047-02), NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NHMRC | Epidemiology of Chronic D... (209057), NIH | Mayo Clinic SPORE in Ovar... (3P50CA136393-05S1), NHMRC | Towards cancer control: P... (199600), NIH | COLLABORATIVE STUDY OF OV... (5R01CA058598-05),...

    RNA editing in mammals is a form of post-transcriptional modification in which adenosine is converted to inosine by the adenosine deaminases acting on RNA (ADAR) family of enzymes. Based on evidence of altered ADAR expression in epithelial ovarian cancers (EOC), we hypo...

  • publication . Article . Other literature type . 2016
    Open Access
    Authors:
    Alice Lee; Penelope Webb; Allan Jensen; Signe Marie Jensen; Estrid Høgdall; Susan Ramus; Stacey Winham; Usha Menon; Lambertus Kiemeney;
    Publisher: Elsevier BV
    Project: NIH | Training Grant in Genomic... (5T32ES013678-05), NHMRC | Molecular Epidemiology of... (400281), NIH | Genetic Epidemiology of O... (5K07CA143047-02), NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MOLECULAR EPIDEMIOLOGY OF... (5R01CA076016-04), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN025403-000), NIH | CASE CONTROL STUDY OF OVA... (5R01CA074850-05), NIH | NORTHERN CALIFORNIA COOPE... (5U01CA069417-02), NIH | DNA POLYMORPHISMS IN OVAR... (5R01CA080742-04),...

    PURPOSE: Socioeconomic status (SES) is a known predictor of survival for several cancers and it has been suggested that SES differences affecting tumour stage at diagnosis may be the most important explanatory factor for this. However, only a limited number of studies h...

  • publication . Article . 2019
    Open Access English
    Authors:
    Kim, S.; Wang, M.; Tyrer, J. P.; Jensen, A.; Wiensch, A.; Liu, G.; Lee, A. W.; Ness, R. B.; Salvatore, M.; Tworoger, S. S.; ...
    Project: NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NIH | PCOS, Type II diabetes an... (5K22CA193860-03), NIH | Training Grant in Genomic... (5T32ES013678-05), NIH | Steroid Hormone Genes and... (5R01CA112523-03), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | SURVEILLANCE, EPIDEMIOLOG... (N01CN067001-000), NIH | MOLECULAR EPIDEMIOLOGY OF... (5R01CA076016-04), NIH | Long Term Multidisciplina... (5UM1CA186107-05), NIH | RISK FACTORS AND PROGNOST... (1R01CA061107-01), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01PC067010-000),...

    As a follow-up to genome-wide association analysis of common variants associated with ovarian carcinoma (cancer), this study considers seven well-known ovarian cancer risk factors and their interactions with 28 genome-wide significant common genetic variants. The intera...

5 research outcomes, page 1 of 1
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