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438 research outcomes, page 1 of 44
  • publication . Article . 2017
    Open Access English
    Authors:
    Cho, Christina; Hsu, Meier; Barba, Pere; Maloy, Molly A.; Avecilla, Scott T.; Barker, Juliet N.; Castro-Malaspina, Hugo; Giralt, Sergio A.; Jakubowski, Ann A.; Koehne, Guenther; ...
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MARROW TRANSPLANTATION IN... (5P01CA023766-14)

    Altres ajuts: This research was supported in part by National Institutes of Health award number P01 CA23766 and NIH/NCI Cancer Center Support Grant P30 CA008748. The content is solely the responsibility of the authors and does not necessarily represent the official view...

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Audrey Mauguen;
    Publisher: Springer Nature
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Statistical Strategies fo... (5R01CA163251-03)

    Background Recent evidence suggests that lobular carcinoma in situ (LCIS) can be a clonal precursor of invasive breast cancers of both the ductal and lobular phenotypes. We sought to confirm these findings with an extensive study of fresh frozen breast specimens from wo...

  • publication . Preprint . 2019
    Open Access English
    Authors:
    Tan, Jiaxing; Jing, Longlong; Huo, Yumei; Tian, Yingli; Akin, Oguz;
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Lung segmentation in computerized tomography (CT) images is an important procedure in various lung disease diagnosis. Most of the current lung segmentation approaches are performed through a series of procedures with manually empirical parameter adjustments in each step...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    GIUSEPPE PETRALIA; David Collins; Giuseppe PETRALIA; STEFANO FANTI; Dow-Mu Koh;
    Publisher: European Association of Urology. Published by Elsevier B.V.
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Context Comparative reviews of whole-body magnetic resonance imaging (WB-MRI) and positron emission tomography/computed tomography (CT; with different radiotracers) have shown that metastasis detection in advanced cancers is more accurate than with currently used CT and...

  • publication . Article . 2016
    Open Access English
    Authors:
    Michael Hoffmeister; Richard Hayes; Bette Caan; Fredrick Schumacher; Tabitha Harrison; Stephanie Bien; Sébastien KÜRY; Mark Jenkins; Hermann Brenner;
    Publisher: Public Library of Science
    Project: NIH | Cancer Prevention Trainin... (5R25CA094880-12), NIH | Hormones and Colon Cancer... (5R01CA076366-07), NIH | Ontario Registry for Stud... (3U01CA074783-09S2), NIH | Cancer Epidemiology Cohor... (5UM1CA167552-02), NIH | A Whole Genome Admixture ... (3R01CA063464-09S1), NIH | EPIDEMIOLOGIC STUDIES OF ... (5P01CA033619-05), NIH | DIET, HORMONES AND RISK O... (3P01CA087969-03S1), NIH | AROMATIC AMINES AND COLON... (5R01CA060987-03), NIH | NUTRITIONAL AND BIOCHEMIC... (5R01CA042182-09), NIH | AUSTRALASIAN COLORECTAL C... (5U01CA097735-05),...

    Genome-wide association studies (GWAS) have identified many common single nucleotide polymorphisms (SNPs) associated with colorectal cancer risk. These SNPs may tag correlated variants with biological importance. Fine-mapping around GWAS loci can facilitate detection of...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Oakley Olson;
    Publisher: Elsevier
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Mechanisms of Macrophage ... (1F31CA171384-01)

    SUMMARY Antimitotic agents, including Taxol, disrupt microtubule dynamics and cause a protracted mitotic arrest and subsequent cell death. Despite the broad utility of these drugs in breast cancer and other tumor types, clinical response remains variable. Tumor-associat...

  • publication . Article . 2017
    Open Access English
    Authors:
    Zelenetz, Andrew D.; Barrientos, Jacqueline C.; Brown, Jennifer R.; Coiffier, Bertrand; Delgado, Julio; Egyed, Miklós; Ghia, Paolo; Illés, Árpád; Jurczak, Wojciech; Marlton, Paula; ...
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Summary Background: Bendamustine and rituximab (BR) has been a standard of care for the management of patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL). We evaluated the efficacy and safety of adding idelalisib, a first-in-class targeted PI3Kδ i...

  • publication . Article . 2019
    Open Access English
    Authors:
    Mazzu, Ying Z.; Hu, Yulan; Shen, Yawei; Tuschl, Thomas; Singer, Samuel;
    Publisher: Nature Publishing Group
    Project: NIH | Administrative Core (5P50CA140146-04), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Biochemical and structura... (5U19CA179564-02)

    Abstract Liposarcoma is the most common soft tissue sarcoma. Molecularly targeted therapeutics have had limited efficacy in liposarcomas, in part because of inadequate knowledge of the complex molecular alterations in these tumors. Our recent study revealed the tumor su...

  • publication . Article . 2017
    Open Access English
    Authors:
    Mary Elizabeth Davis;
    Publisher: Wolters Kluwer Medknow Publications
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    : Retinoblastoma (RB) is the most common primary cancer to affect the eyes in children with approximately 350 cases/year in the United States and 8000 worldwide. Today, sadly, 50% of children with RB worldwide die from their disease. In our experience, utilization of op...

  • publication . Article . 2020
    Open Access English
    Authors:
    Elizabeth Morris; Rahel A. Kubik-Huch; May Abdel-Wahab; Elizabeth Balogun; Charlotte Beardmore; Regina Beets-Tan; Aidan Boyd-Thorpe; Lorenzo Derchi; Michael Fuchsjäger; Janet Husband; ...
    Publisher: SpringerOpen
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Abstract The 2019 European Congress of Radiology program, “Women in Focus: Be Inspired,” offered insights from successful women and men for overcoming a number of everyday work and personal life challenges. With regard to balancing career and personal life and achieving...

438 research outcomes, page 1 of 44
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