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6 research outcomes, page 1 of 1
  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    P. Hammel; H.L. Kindler; M. Reni; E. Van Cutsem; T. Macarulla; M.J. Hall; J.O. Park; D. Hochhauser; D. Arnold; D.-Y. Oh; ...
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    BACKGROUND: Patients with metastatic pancreatic cancer often have a detriment in health-related quality of life (HRQoL). In the randomized, double-blind, phase III POLO trial progression-free survival was significantly longer with maintenance olaparib, a poly(ADP-ribose...

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Andrew J Vickers; Ben Van Calster; Ewout W Steyerberg;
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Dynamic, multi-cohort pre... (5R01CA179115-02), EC | CENTER-TBI (602150), NIH | RATIONAL DESIGN OF PROSTA... (5P50CA092629-10)

    © BMJ Publishing Group Ltd 2016. Many decisions in medicine involve trade-offs, such as between diagnosing patients with disease versus unnecessary additional testing for those who are healthy. Net benefit is an increasingly reported decision analytic measure that puts ...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Vickers, Andrew J.; van Calster, Ben; Steyerberg, Ewout W.;
    Publisher: BMC
    Project: NIH | Value of Personalized Ris... (3U01NS086294-01S1), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | RATIONAL DESIGN OF PROSTA... (5P50CA092629-10)

    Background: Decision curve analysis is a method to evaluate prediction models and diagnostic tests that was introduced in a 2006 publication. Decision curves are now commonly reported in the literature, but there remains widespread misunderstanding of and confusion abou...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Fittall, Matthew W; Mifsud, William; Pillay, Nischalan; Ye, Hongtao; Strobl, Anna-Christina; Verfaillie, Annelien; Demeulemeester, Jonas; Zhang, Lei; Berisha, Fitim; Tarabichi, Maxime; ...
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), WT , EC | SIOMICS (747852), NIH | Administrative Core (5P50CA140146-04), EC | DECODE (703594)

    The transcription factor FOS has long been implicated in the pathogenesis of bone tumours, following the discovery that the viral homologue, v-fos, caused osteosarcoma in laboratory mice. However, mutations of FOS have not been found in human bone-forming tumours. Here,...

  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Bick, Ulrich; Trimboli, Rubina M; Athanasiou, Alexandra; Balleyguier, Corinne; Baltzer, Pascal AT; Bernathova, Maria; Borbély, Krisztina; Brkljacic, Boris; Carbonaro, Luca A; Clauser, Paola; ...
    Publisher: Springer Berlin Heidelberg
    Project: NWO | XCiDE: Crossing the Combu... (2300153186), NIH | MOUSE GENETICS (2P30CA008748-43), EC | HYPMED (667211), EC | CANCER SCAN (828978)

    We summarise here the information to be provided to women and referring physicians about percutaneous breast biopsy and lesion localisation under imaging guidance. After explaining why a preoperative diagnosis with a percutaneous biopsy is preferred to surgical biopsy, ...

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Thilo Dörk; Stuart MacGregor; Sara Olson; Anna Jakubowska; Liisa M Pelttari; Susan Ramus; Tomasz Kluz; Ian Campbell; Jolanta Lissowska; Yi Lu; ...
    Publisher: eScholarship, University of California
    Project: NIH | Mayo Clinic SPORE in Ovar... (3P50CA136393-05S1), NHMRC | Towards cancer control: P... (199600), NIH | COLLABORATIVE STUDY OF OV... (5R01CA058598-05), NIH | Steroid Hormone Genes and... (5R01CA112523-03), NIH | Regulatory T Cell Functio... (5R01CA126841-04), NIH | HEREDITARY BREAST CANCER-... (5R01CA058860-02), NIH | Ovarian Cancer and Gonado... (5R03CA115195-02), NIH | Premenopausal Hormone Lev... (5R01CA067262-08), NIH | The Mitochondrial Genome ... (5R01CA149429-05), NIH | MOUSE GENETICS (2P30CA008748-43),...

    BACKGROUND: In vitro and observational epidemiological studies suggest that vitamin D may play a role in cancer prevention. However, the relationship between vitamin D and ovarian cancer is uncertain, with observational studies generating conflicting findings. A potenti...

6 research outcomes, page 1 of 1
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