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28 research outcomes, page 1 of 3
  • publication . Other literature type . Article . 2017
    Open Access
    Authors:
    David Liu; Philip Abbosh; Daniel Keliher; Brendan Reardon; Diana Miao; Kent Mouw; Amaro Weiner-Taylor; Stephanie Wankowicz; Garam Han; Min Yuen Teo; ...
    Publisher: Springer Science and Business Media LLC
    Project: NIH | Resistance to Emerging An... (5K08CA188615-02), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Comprehensive Cancer Cent... (3P30CA006927-50SD)

    Despite continued widespread use, the genomic effects of cisplatin-based chemotherapy and implications for subsequent treatment are incompletely characterized. Here, we analyze whole exome sequencing of matched pre- and post-neoadjuvant cisplatin-based chemotherapy prim...

  • publication . Article . 2013
    Open Access English
    Authors:
    Jolanta Lissowska; Carlotta Sacerdote; Fredrick Schumacher; Christine Friedenreich; Sara Olson; Veronica Setiawan; Jirong Long; Marta Crous-Bou; Amanda Spurdle; Alison Margaret Dunning; ...
    Publisher: Springer Berlin Heidelberg
    Project: NIH | Epidemiology of Ovarian C... (5R01CA087538-02), NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Molecular Epidemiology of... (1R01CA105212-01A1), NIH | CALIFORNIA TEACHERS STUDY (5R01CA077398-09), NIH | Genome-Wide Association S... (5R01CA134958-02), NIH | GENES AND THE ESTROGEN EF... (1R01CA091019-01A1), NIH | GENETIC SUSCEPTIBILITY TO... (5R01CA082838-04), NIH | MOLECULAR EPIDEMIOLOGIC S... (1R01CA090899-01), NHMRC | Molecular Epidemiology of... (339435),...

    Endometrial cancer (EC), a neoplasm of the uterine epithelial lining, is the most common gynecological malignancy in developed countries and the fourth most common cancer among US women. Women with a family history of EC have an increased risk for the disease, suggestin...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Ostrom, Quinn T.; Kinnersley, Ben; Wrensch, Margaret R.; Eckel-Passow, Jeanette E.; Armstrong, Georgina; Rice, Terri; Chen, Yanwen; Wiencke, John K.; McCoy, Lucie S.; Hansen, Helen M.; ...
    Publisher: Nature Publishing Group UK
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | BRAIN TUMOR SPORT GRANT (5P50CA097257-12), NIH | Genetic and Molecular Epi... (5R01CA052689-13), NIH | Clinical and Translationa... (3UL1RR024131-03S3), NIH | Baylor College of Medicin... (3P30CA125123-09S3), WT , NIH | International Case Contro... (1R01CA139020-01A1), NIH | CALIFORNIA COORDINATED CA... (1U58DP003862-01), NIH | Biomarkers of survival in... (5R01CA126831-04)

    <p>Incidence of glioma is approximately 50% higher in males. Previous analyses have examined exposures related to sex hormones in women as potential protective factors for these tumors, with inconsistent results. Previous glioma genome-wide association studies (GWAS) ha...

  • publication . Article . Preprint . Other literature type . 2018
    Open Access
    Authors:
    Irtisha Singh; Shih-Han Lee; Adam S. Sperling; Mehmet K. Samur; Yu-Tzu Tai; Mariateresa Fulciniti; Nikhil C. Munshi; Christine Mayr; Christina S. Leslie;
    Publisher: Springer Science and Business Media LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | 3'UTR-mediated protein-pr... (5DP1GM123454-02), NIH | Dissecting the role of al... (5U01CA164190-03)

    Alternative cleavage and polyadenylation (ApA) is known to alter untranslated region (3ʹUTR) length but can also recognize intronic polyadenylation (IpA) signals to generate transcripts that lose part or all of the coding region. We analyzed 46 3ʹ-seq and RNA-seq profil...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Jeong, Sangmoo; Eskandari, Roozbeh; Park, Sun Mi; Alvarez, Julio; Tee, Sui Seng; Weissleder, Ralph; Kharas, Michael G.; Lee, Hakho; Keshari, Kayvan R.;
    Publisher: American Association for the Advancement of Science
    Project: NIH | uCoil NMR platform for ro... (5R21CA212958-02), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Human Tissue Culture Bior... (5R00EB014328-03), NIH | MAGNETIC NANOSENSORS FOR ... (1R01HL113156-01), NIH | Multiplexed exosome analy... (1R21CA205322-01)

    Hyperpolarized micro-NMR nondestructively analyzes metabolic activities in scant cells.

  • publication . Article . 2016
    Open Access English
    Authors:
    Jolanta Lissowska; Sara Olson; Zachary Fogarty; yian Chen; Peter Kraft; Hui-Yi Lin; Alvaro Monteiro; Jeremy Chien; Stacey Winham;
    Publisher: Impact Journals LLC
    Project: CIHR , NIH | USC COMPREHENSIVE CANCER ... (3P30CA014089-17S1), NIH | CASE-CONTROL STUDY OF OVA... (1R01CA061132-01), NIH | Genes, Hormones &Environm... (5R01CA054419-14), NIH | MOLECULAR EPIDEMIOLOGY OF... (5R01CA076016-04), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN025403-000), NIH | Mayo Clinic SPORE in Ovar... (3P50CA136393-05S1), NIH | COLLABORATIVE STUDY OF OV... (5R01CA058598-05), NIH | CANCER CENTER SUPPORT GRA... (3P30CA072720-07S2), NIH | OVARIAN CANCER RISK AND S... (5K07CA080668-06),...

    Background: Genome-wide association studies have identified several common susceptibility alleles for epithelial ovarian cancer (EOC). To further understand EOC susceptibility, we examined previously ungenotyped candidate variants, including uncommon variants and those ...

  • publication . Article . 2016
    Open Access
    Authors:
    Alexander Pietras; Bengt Westermark;
    Publisher: Springer Science and Business Media LLC
    Project: NIH | Evolutionary Dynamics of ... (4U54CA143798-03), NIH | P3IK Signaling and Biolog... (5U01CA141502-03), NIH | Role of the Perivascular ... (5U54CA163167-04), NIH | MOUSE GENETICS (2P30CA008748-43)

    Glioma cells with stem cell traits are thought to be responsible for tumor maintenance and therapeutic failure. Such cells can be enriched based on their inherent drug efflux capability mediated by the ABC transporter ABCG2 using the side population assay, and their cha...

  • publication . Article . 2017
    Open Access
    Authors:
    Hongxin Zhang; Jianjiong Gao;
    Publisher: Springer Science and Business Media LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MSKCC Center for Translat... (5U24CA143840-04)

    Many mutations in cancer are of unknown functional significance. Standard methods use statistically significant recurrence of mutations in tumor samples as an indicator of functional impact. We extend such analyses into the long tail of rare mutations by considering rec...

  • publication . Article . 2017
    Open Access
    Authors:
    Riester, Markus; Wu, Hua-Jun; Zehir, Ahmet; Gönen, Mithat; Moreira, Andre L.; Downey, Robert J.; Michor, Franziska;
    Publisher: Public Library of Science (PLoS)
    Project: NIH | Administrative Core (1U54CA193461-01), NIH | Evolutionary Dynamics of ... (4U54CA143798-03), NIH | MOUSE GENETICS (2P30CA008748-43)

    : The degree of histologic cellular differentiation of a cancer has been associated with prognosis but is subjectively assessed. We hypothesized that information about tumor differentiation of individual cancers could be derived objectively from cancer gene expression d...

  • publication . Article . 2015
    Open Access English
    Authors:
    Jolanta Lissowska; Giske Ursin; Christine Friedenreich; Fredrick Schumacher; Sara Olson; Veronica Setiawan; Peter Kraft;
    Publisher: Public Library of Science
    Project: NIH | Epidemiology of Ovarian C... (5R01CA087538-02), NIH | ENDOMETRIAL CANCER AND PO... (1R01CA075977-01), NIH | A Whole Genome Admixture ... (3R01CA063464-09S1), NIH | Role of Genetic and Lifes... (1R01CA098346-01A1), NIH | CALIFORNIA TEACHERS STUDY (5R01CA077398-09), NIH | Genome-Wide Association S... (5R01CA134958-02), NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NIH | BREAST CANCER AND THE BIR... (N01HD023166-008), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN067009-004), NIH | GENES AND THE ESTROGEN EF... (1R01CA091019-01A1),...

    Genome-wide association studies (GWAS) have identified common variants that predispose individuals to a higher body mass index (BMI), an independent risk factor for endometrial cancer. Composite genotype risk scores (GRS) based on the joint effect of published BMI risk ...

28 research outcomes, page 1 of 3
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