2 research outcomes, page 1 of 1
- publication . Article . Other literature type . 2016Open AccessAuthors:Jonas Sokolof; Kate Fife; Rainer Kunstfeld; Rogerio I. Neves; Reinhard Dummer; Aleksandar Sekulic; Scott Ernst; Ketty Peris; Axel Hauschild; Nicole Basset-Seguin; ...Publisher: WileyProject: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Genetic Epidermiology of ... (1R01CA083115-01A2)
Vismodegib and sonidegib are Hedgehog pathway inhibitors (HPIs) approved for treatment of patients with advanced basal cell carcinoma. The adverse events (AEs) associated with these therapies can impact clinical outcomes as a result of decreased quality of life and trea...
- publication . Other literature type . Article . 2019Open AccessAuthors:Jordi Rodon; Heiko Maacke; Martijn P. Lolkema; Mike Thomas; Joe Stephenson; Aditya Bardia; Martin Schuler; Mrinal M. Gounder; Cristiana Sessa; Yongjian Sun; ...pmc: PMC6964137pmid: 31395751Publisher: Alphamed PressProject: NIH | MOUSE GENETICS (2P30CA008748-43)
Abstract Background This multicenter, open‐label, phase Ib study investigated the safety and efficacy of binimetinib (MEK inhibitor) in combination with buparlisib (phosphatidylinositol 3‐kinase [PI3K] inhibitor) in patients with advanced solid tumors with RAS/RAF alter...
2 research outcomes, page 1 of 1
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