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6 research outcomes, page 1 of 1
  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Elisabeth F. P. Peterse; Reinier G. S. Meester; Rebecca L. Siegel; Jennifer C. Chen; Andrea Dwyer; Dennis J. Ahnen; Robert A. Smith; Ann G. Zauber; Iris Lansdorp-Vogelaar;
    Project: NIH | Comparative Modeling of C... (5U01CA199335-03), NIH | MOUSE GENETICS (2P30CA008748-43)

    BACKGROUND In 2016, the Microsimulation Screening Analysis‐Colon (MISCAN‐Colon) model was used to inform the US Preventive Services Task Force colorectal cancer (CRC) screening guidelines. In this study, 1 of 2 microsimulation analyses to inform the update of the Americ...

  • publication . Article . Other literature type . 2016
    Open Access
    Authors:
    marco zappa; Arnauld VILLERS; Anssi Auvinen;
    Publisher: Wiley
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Modeling prostate cancer ... (5U01CA157224-03), NIH | RATIONAL DESIGN OF PROSTA... (5P50CA092629-10), NIH | Prospective validation of... (5R01CA160816-02)

    BACKGROUND: Prostate-specific antigen (PSA) screening and concomitant treatment can be implemented in several ways. The authors investigated how the net benefit of PSA screening varies between common practice versus “good practice.”. METHODS: Microsimulation screening a...

  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    Oliver Sartor; David Penson; Andrew Armstrong;
    Publisher: Wiley
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Background The large registry, PROVENGE Registry for the Observation, Collection, and Evaluation of Experience Data (PROCEED)(NCT01306890), evaluated sipuleucel‐T immunotherapy for asymptomatic/minimally symptomatic metastatic castration‐resistant prostate cancer (mCRPC...

  • publication . Article . 2018
    Open Access
    Authors:
    Grivas, Petros; Mortazavi, Amir; Picus, Joel; Hahn, Noah M.; Milowsky, Matthew I.; Hart, Lowell L.; Alva, Ajjai; Bellmunt, Joaquim; Pal, Sumanta K.; Bambury, Richard M.; ...
    Publisher: Wiley
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Abstract Background The authors evaluated mocetinostat (a class I/IV histone deacetylase inhibitor) in patients with urothelial carcinoma harboring inactivating mutations or deletions in CREB binding protein [CREBBP] and/or E1A binding protein p300 [EP300] histone acety...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Shreyaskumar Patel; Margaret von Mehren; Damon R. Reed; Pamela Kaiser; John Charlson; Christopher W. Ryan; Daniel Rushing; Michael Livingston; Arun Singh; Rahul Seth; ...
    Publisher: John Wiley and Sons Inc.
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    A final analysis of overall survival demonstrates comparable results between patients with liposarcoma/leiomyosarcoma receiving trabectedin or dacarbazine, which is consistent with interim analysis results. Both liposarcoma and leiomyosarcoma show improved disease contr...

  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Reinier G. S. Meester; Elisabeth F. P. Peterse; Amy B. Knudsen; Anne C. de Weerdt; Jennifer C. Chen; Anna P. Lietz; Andrea Dwyer; Dennis J. Ahnen; Rebecca L. Siegel; Robert A. Smith; ...
    Publisher: Wiley
    Project: NIH | Comparative Modeling of C... (5U01CA199335-03), NIH | MOUSE GENETICS (2P30CA008748-43)

    An established modeling method suggests that screening should be considered from the age of 45 years for African American men and women, and for white men and women if their lifetime risk of colorectal cancer increases similarly to trends observed at younger ages. See a...

6 research outcomes, page 1 of 1
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