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4 research outcomes, page 1 of 1
  • publication . Article . 2020
    Open Access English
    Authors:
    Maha Mamoor; Michael A Postow; Jessica A Lavery; Shrujal S Baxi; Niloufer Khan; Jun J Mao; Lauren J Rogak; Robert Sidlow; Bridgette Thom; Jedd A Wolchok; ...
    Publisher: BMJ Publishing Group
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    <jats:sec><jats:title>Background</jats:title><jats:p>Immune checkpoint inhibitors (CIs) have revolutionized treatment of advanced melanoma, leading to an emerging population of long-term survivors. Survivors’ quality of life (QOL) and symptom burden are poorly understoo...

  • publication . Article . 2018
    Open Access English
    Authors:
    Konstantina Matsoukas;
    Publisher: BioMed Central
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Abstract Background Cytokine release syndrome (CRS) has been reported after immunologic manipulations, most often through therapeutic monoclonal antibodies. To our knowledge, CRS after radiation therapy (RT) for cancer has not been reported before. The development of un...

  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Cody Chiuzan;
    Publisher: Columbia University
    Project: NIH | Phase I Designs for Combi... (5K25CA181638-05), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Clinical and Translationa... (5UL1TR001873-03)

    Background With numerous and fast approvals of different agents including immune checkpoint inhibitors, monoclonal antibodies, or chimeric antigen receptor (CAR) T-cell therapy, immunotherapy is now an established form of cancer treatment. These agents have demonstrated...

  • publication . Article . 2018
    Open Access
    Authors:
    Eileen M. O'Reilly; Monika Vyas;
    Publisher: BMJ
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Abstract Background MMR-D pancreatic cancer have been reported to respond to checkpoint inhibitor therapy. Here, we report the first case of acquired resistance to immunotherapy in MMR-D pancreatic cancer. Case presentation A 45-year-old woman with unresectable MMR-D pa...

4 research outcomes, page 1 of 1
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