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6 research outcomes, page 1 of 1
  • publication . Article . 2019
    Open Access English
    Authors:
    Gini F. Fleming; B.D. Green; Kyle Hernandez; Kathleen R. Bowie; Caroline R. Kim; Mayra A. Betancourt-Ponce; Eva Tonsing-Carter; Ryan V. Harkless; Sarat Chandarlapaty; Diana C. West-Szymanski; ...
    Publisher: BMC
    Project: NIH | Investigate the role of T... (1R01CA196648-01A1), NIH | Therapeutic approaches to... (1R01CA204999-01A1), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Glucocorticoid receptor-m... (5R01CA089208-08), NIH | Cancer Center Support Gra... (3P30CA014599-36S1)

    Background Non-ER nuclear receptor activity can alter estrogen receptor (ER) chromatin association and resultant ER-mediated transcription. Consistent with GR modulation of ER activity, high tumor glucocorticoid receptor (GR) expression correlates with improved relapse-...

  • publication . Article . Other literature type . 2016
    Open Access
    Authors:
    Michail Schizas; Dilip Giri; Colin B. Begg; Venkatraman E. Seshan; Victor P. Andrade; Tari A. King; Audrey Mauguen; Irina Ostrovnaya; Russell Towers; Rita A. Sakr; ...
    Publisher: Springer Science and Business Media LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Statistical Strategies fo... (5R01CA163251-03)

    Background Recent evidence suggests that lobular carcinoma in situ (LCIS) can be a clonal precursor of invasive breast cancers of both the ductal and lobular phenotypes. We sought to confirm these findings with an extensive study of fresh frozen breast specimens from wo...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Daly Avendano; Daly Avendano; Pascal A. T. Baltzer; Katja Pinker; Katja Pinker; Doris Leithner; Danny F. Martinez; Paola Clauser; Panagiotis Kapetas; Sunitha B. Thakur; ...
    Publisher: BioMed Central
    Project: EC | MURAB (688188), NIH | MOUSE GENETICS (2P30CA008748-43), EC | CANCER SCAN (828978), EC | HYPMED (667211)

    <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Available data proving the value of DWI for breast cancer diagnosis is mainly for enhancing masses; DWI may be less sensitive and specific in non-mass enhancement (NME) lesions. The ...

  • publication . Article . 2016
    Open Access
    Authors:
    Esther M. John; Esther M. John; Leslie Bernstein; Lene Mellemkjær; Jonine L. Bernstein; Patrick Concannon; Meghan Woods; Kathleen E. Malone; Anne S. Reiner; Rikke Langballe; ...
    Publisher: Springer Science and Business Media LLC
    Project: NIH | Breast Cancer, Radiation ... (5R01CA114236-02), NIH | BREAST CANCER, RADIATION ... (5U01CA083178-02), NIH | Interaction of Radiation,... (5R01CA097397-03), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Genome-Wide Association S... (5R01CA129639-05)

    Background Treatment with tamoxifen or chemotherapy reduces the risk of contralateral breast cancer (CBC). However, it is uncertain how long the protection lasts and whether the protective effect is modified by patient, tumor, or treatment characteristics. Methods The p...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Blanca Bernard-Davila; Maxine S. Jochelson; Danny F. Martinez; Joao V. Horvat; Katja Pinker; Elizabeth A. Morris; Sunitha B. Thakur; Maria Adele Marino; Maria Adele Marino; Doris Leithner; ...
    Publisher: BioMed Central
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), EC | HYPMED (667211)

    <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>To evaluate the diagnostic performance of radiomic signatures extracted from contrast-enhanced magnetic resonance imaging (CE-MRI) for the assessment of breast cancer receptor statu...

  • publication . Article . 2010
    Open Access English
    Authors:
    Katrina Podsypanina; Kenneth Leslie; Hao Ho; Lionel B. Ivashkiv; Marjan Berishaj; Jacqueline Bromberg; Sizhi P. Gao;
    Publisher: Springer Nature
    Project: NIH | Role of Stat3 in Breast C... (5R01CA087637-03), NIH | MOUSE GENETICS (2P30CA008748-43)

    Introduction Tyrosine phosphorylated signal transducer and activator of transcription 3 (pStat3) is expressed in numerous cancers and is required for mediating tumorigenesis. Autocrine and paracrine interleukin (IL)-6 signaling is the principal mechanism by which Stat3 ...

6 research outcomes, page 1 of 1