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4 research outcomes, page 1 of 1
  • publication . Article . Preprint . 2016
    Open Access English
    Authors:
    Timothy O’Donnell; Elizabeth L. Christie; Arun Ahuja; Jacqueline Buros; B. Arman Aksoy; David D. L. Bowtell; Alexandra Snyder; Jeff Hammerbacher;
    Publisher: BioMed Central
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    <jats:sec id="s1"><jats:title>Background</jats:title><jats:p>Patients with highly mutated tumors, such as melanoma or smoking-related lung cancer, have higher rates of response to immune checkpoint blockade therapy, perhaps due to increased neoantigen expression. Many c...

  • publication . Article . 2017
    Open Access English
    Authors:
    Sally Temraz; Sara Olson;
    Publisher: BioMed Central
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Abstract Background Providing an estimate of the percentage of cancer in Lebanon by 2018 that is due to the exposure to risk factors in 2008. Factors include: smoking, body mass index (BMI), physical inactivity, dietary factors, alcohol consumption, infections, and air ...

  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Gulisa Turashvili; Edi Brogi; Monica Morrow; Maura Dickler; Larry Norton; Clifford Hudis; Hannah Y. Wen;
    Publisher: Springer Science and Business Media LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Abstract Background The 21-gene recurrence score (RS) assay determines the benefit of adding chemotherapy to endocrine therapy for patients with early stage, estrogen receptor (ER)-positive, HER2-negative breast cancer. The RS risk groups predict the likelihood of dista...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Ibrahim H. Sahin; Harold Elias; Joanne F. Chou; Marinela Capanu; Eileen M. O’Reilly;
    Publisher: BioMed Central
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers with high metastatic potential. Clinical observations suggest that there is disease heterogeneity among patients with different sites of distant metastases, yielding distin...

4 research outcomes, page 1 of 1
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