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34 research outcomes, page 1 of 4
  • publication . Article . 2019
    Open Access
    Authors:
    Paul, Debamita; Mu, Hong; Zhao, Hong; Ouerfelli, Ouathek; Jeffrey, Philip D; Broyde, Suse; Min, Jung-Hyun;
    Publisher: Oxford University Press (OUP)
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NSF | Unveiling how the XPC nuc... (1412692), NIH | Environmental Carcinogen-... (9R01ES025987-35A1), NIH | Arylamine DNA adduct reco... (1R21ES028384-01)

    <jats:title>Abstract</jats:title> <jats:p>Failure in repairing ultraviolet radiation-induced DNA damage can lead to mutations and cancer. Among UV-lesions, the pyrimidine–pyrimidone (6-4) photoproduct (6-4PP) is removed from the genome much faster than the cyclobutane p...

  • publication . Preprint . 2020
    Open Access English
    Authors:
    Matthew F Wipperman; Shakti K Bhattarai; Charles Kyriakos Vorkas; Ying Taur; Laurent Mathurin; Katherine McAulay; Stalz Charles Vilbrun; Daphie Jean Francois; James Bean; Kathleen F Walsh; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | The role of Mucosal-assoc... (1K08AI132739-01A1), NIH | J NRSA Training Core (1TL1TR002386-01), NSF | ABI Innovation: A new com... (1458347), NIH | Pharmacology (1U19AI111143-01)

    <jats:p>Antibiotic therapy cures infection predominantly by killing the infecting pathogen, but for infections such as tuberculosis (TB), which are accompanied by chronic inflammation, the salutary effects of antibiotic therapy may reflect a combination of pathogen kill...

  • publication . Article . 2010
    Open Access English
    Authors:
    Stefan Knirr; Janette Gomos-Klein; Blanca E. Andino; Faith Harrow; Karl F. Erhard; Damian Kovalovsky; Derek B. Sant'Angelo; Benjamin D. Ortiz;
    Publisher: Public Library of Science (PLoS)
    Project: NSF | CAREER: DNA Elements Invo... (0236964), NIH | Chromatin based gene regu... (1R21AI053050-01), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Clinical and Translationa... (3UL1RR024996-03S2), NIH | RESEARCH CENTER FOR STUDY... (2G12RR003037-16), NIH | HUNTER COLLEGE MARC PROGR... (3T34GM007823-17S1), NIH | Immunology Research Train... (5T32CA009149-28), NIH | RISE Program at Hunter Co... (2R25GM060665-05)

    The molecular mechanisms regulating the activity of the TCRα gene are required for the production of the circulating T cell repertoire. Elements of the mouse TCRα locus control region (LCR) play a role in these processes. We previously reported that TCRα LCR DNA support...

  • publication . Preprint . Other literature type . 2018
    Open Access English
    Authors:
    Fanning, Sean W.; Jeselsohn, Rinath; Dharmarajan, Venkatasubramanian; Mayne, Christopher G.; Karimi, Mostafa; Buchwalter, Gilles; Houtman, Rene; Toy, Weiyi; Fowler, Colin E.; Lainé, Muriel; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | Therapeutic approaches to... (1R01CA204999-01A1), NIH | Chemical, structural and ... (1R01CA220284-01A1), NIH | MOUSE GENETICS (2P30CA008748-43), NSERC , NIH | Unraveling molecular and ... (5R35GM124952-02), CIHR , NSF | CCF: EAGER: Dimension Red... (1546278)

    <jats:title>Abstract</jats:title><jats:p>Acquired resistance to endocrine therapy remains a significant clinical burden for breast cancer patients. Somatic mutations in the <jats:italic>ESR1</jats:italic> (estrogen receptor alpha (ERα) gene ligand-binding domain (LBD) r...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Stefan Harmsen;
    Publisher: Ivyspring International Publisher
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | The Ivis Spectrum CT for ... (1S10OD016207-01), NIH | MRI-Photoacoustic-Raman N... (1R01EB017748-01A1), NSF | IGERT: Returning the Radi... (0965983)

    : A single contrast agent that offers whole-body non-invasive imaging along with the superior sensitivity and spatial resolution of surface-enhanced resonance Raman scattering (SERRS) imaging would allow both pre-operative mapping and intraoperative imaging and thus be ...

  • publication . Preprint . 2019
    Open Access English
    Authors:
    Liu, Jingya; Cao, Liangliang; Akin, Oguz; Tian, Yingli;
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NSF | CHS: Medium: Collaborativ... (1400802)

    Comment: 15 pages, 8 figures, 5 tables, under review by Medical Image Analysis. arXiv admin note: substantial text overlap with arXiv:1906.03467

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    John Kang;
    Publisher: Frontiers Media S.A.
    Project: NSF | CAREER: Dissecting the Me... (1149885), NIH | Genome-Wide Study to Iden... (5R01CA134444-02), NIH | Risk Prediction for Devel... (5K07CA187546-04), NIH | DECONVOLUTION OF CLONAL H... (5R21CA216452-02), NIH | MOUSE GENETICS (2P30CA008748-43)

    Due to the rapid increase in the availability of patient data, there is significant interest in precision medicine that could facilitate the development of a personalized treatment plan for each patient on an individual basis. Radiation oncology is particularly suited f...

  • publication . Preprint . 2019
    Open Access English
    Authors:
    Li, Qiongge; Pasquini, Luca; Del Ferraro, Gino; Gene, Madeleine; Peck, Kyung K.; Makse, Hernán A.; Holodny, Andrei I.;
    Project: NSF | CRCNS: Targeted Stimulati... (1515022), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Planning and Evaluation (5U54CA137788-03), NIH | Supplement: Network Metho... (3R01EB022720-03S1)

    Pre-surgical language mapping with functional magnetic resonance imaging (fMRI) is routinely conducted to assist the neurosurgeon in preventing damage to brain regions responsible for language. Functional differences exist between the monolingual versus the bilingual br...

  • publication . Article . Other literature type . Preprint . 2017
    Open Access
    Authors:
    Peter Eastman; Jason Swails; John D. Chodera; Robert T. McGibbon; Yutong Zhao; Kyle A. Beauchamp; Lee-Ping Wang; Andrew C. Simmonett; Matthew P. Harrigan; Chaya D. Stern; ...
    Publisher: eScholarship, University of California
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Physics-based Simulation ... (5U54GM072970-04), NIH | Topology, nucleation, and... (1R01GM062868-01A2), NSF | Graduate Research Fellows... (1257284)

    <jats:title>Abstract</jats:title><jats:p>OpenMM is a molecular dynamics simulation toolkit with a unique focus on extensibility. It allows users to easily add new features, including forces with novel functional forms, new integration algorithms, and new simulation prot...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Budhathoki-Uprety, Januka; Shah, Janki; Korsen, Joshua A.; Wayne, Alysandria E.; Galassi, Thomas V.; Cohen, Joseph R.; Harvey, Jackson D.; Jena, Prakrit V.; Ramanathan, Lakshmi V.; Jaimes, Edgar A.; ...
    Publisher: Nature Publishing Group
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Renal tubule-specific nan... (1R01DK114321-01A1), NSF | CAREER: A Quantitative Na... (1752506), NIH | Transient Metabolite Dete... (1DP2HD075698-01)

    Microalbuminuria is an important clinical marker of several cardiovascular, metabolic, and other diseases such as diabetes, hypertension, atherosclerosis, and cancer. The accurate detection of microalbuminuria relies on albumin quantification in the urine, usually via a...

34 research outcomes, page 1 of 4
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