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  • publication . Other literature type . Article . 2015 . Embargo End Date: 13 Feb 2020
    Therapy-induced tumour secretomes promote resistance and tumour progression
    Open Access
    Authors:
    Andrew L. Ji; Hubing Shi; Weiping Shu; Thomas Wiesner; Marcus C. Bosenberg; Sakari Vanharanta; Sakari Vanharanta; Yilong Zou; Anna C. Obenauf; Xiangju Kong; ...
    doi: 10.17863/cam.49134 , 10.1038/nature14336
    pmc: PMC4507807
    View all 4 identifiers
    Publisher: Apollo - University of Cambridge Repository
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), FWF | The impact of stochastic ... (J 3013)

    Tumour cells respond to an effective, targeted drug treatment with BRAF, ALK or EGFR kinase inhibitors by inducing a complex network of secreted signals that promote tumour growth, dissemination and metastasis of drug-resistant cancer cell clones, and increase the survi...

1 research outcomes, page 1 of 1