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  • publication . Other literature type . Article . Preprint . 2019
    The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation
    Open Access
    Authors:
    Julia Batki; Jakob Schnabl; Juncheng Wang; Dominik Handler; Veselin I. Andreev; Christian E. Stieger; Maria Novatchkova; Lisa Lampersberger; Kotryna Kauneckaite; Wei Xie; ...
    doi: 10.1038/s41594-019-0270-6 , 10.1101/609693
    pmc: PMC6828549
    View all 4 identifiers
    Publisher: Springer Science and Business Media LLC
    Project: NIH | Pixel Array Detector for ... (1S10RR029205-01), FWF | RNA Biology (W 1207), EC | PIWI-Chrom (682181), NIH | MOUSE GENETICS (2P30CA008748-43)

    <jats:title>ABSTRACT</jats:title><jats:p>The PIWI-interacting RNA (piRNA) pathway protects animal genome integrity in part through establishing repressive heterochromatin at transposon loci. Silencing requires piRNA-guided targeting of nuclear PIWI proteins to nascent t...

1 research outcomes, page 1 of 1