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6 research outcomes, page 1 of 1
  • publication . Article . Other literature type . 2015
    Open Access
    Authors:
    Bruno Costa-Silva; Tang-Long Shen; Angela Di Giannatale; Sophia Ceder; Hector Peinado; Rajasekhar Vinagolu;
    Publisher: eScholarship, University of California
    Project: NIH | Characterization and Func... (1U01CA169538-01), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Exosome-mediated Transfer... (5R01CA169416-03)

    © 2015 Macmillan Publishers Limited. All rights reserved. Ever since Stephen Paget's 1889 hypothesis, metastatic organotropism has remained one of cancer's greatest mysteries. Here we demonstrate that exosomes from mouse and human lung-, liver- and brain-tropic tumour c...

  • publication . Article . Conference object . Other literature type . 2018
    Open Access
    Authors:
    María Arufe; Jose Catita; Michele Grassi; Jonas Ellegaard Nielsen; Jose Morales-Corraliza; Shona Pedersen; Mariko Saito; Joshua A. Welsh; Stephen Ginsberg; Javier Mariscal; ...
    Publisher: Elsevier BV
    Project: NIH | Primary Hyperoxaluria (5U54DK083908-03), NIH | Molecular mechanism for b... (5R01DK107652-02), NIH | Mechanisms of Cognitive D... (3P01AG022550-06S1), NIH | UCLA SPORE IN PROSTATE CA... (5P50CA092131-05), NIH | West Virginia IDEA-CTR (1U54GM104942-01), EC | GENTRIS (294340), NIH | INTRACELLULAR TRANSPORT--... (5R37DK037332-23), NIH | Novel Mechanistic Targets... (5P01AG027956-06), NIH | Multidisciplinary Trainin... (5T32DK101357-03), FCT | SFRH/BD/90730/2012 (SFRH/BD/90730/2012),...
  • publication . Doctoral thesis . 2020
    Open Access English
    Authors:
    Mafalda Maria Coelho Azevedo;
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Drosophila Genomics Resou... (2P40OD010949-10A1)
  • publication . Article . Other literature type . 2010
    Open Access
    Authors:
    Marta Barreto; Nagahide Takahashi; nicolas ramoz; Joseph D Buxbaum;
    Publisher: Elsevier BV
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | ANIMAL NMR AND RADIONUCLI... (3R24CA083084-04S1)

    Background SLC25A12 , a susceptibility gene for autism spectrum disorders that is mutated in a neurodevelopmental syndrome, encodes a mitochondrial aspartate-glutamate carrier (aspartate-glutamate carrier isoform 1 [AGC1]). AGC1 is an important component of the malate/a...

  • publication . Article . 2020
    Open Access English
    Authors:
    Manhart, A.; Azevedo, M.; Baylies, M.; Mogilner, A.;
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Sizing and Scaling in Fun... (1R01GM121971-01A1)

    How cells position organelles is a fundamental biological question. During Drosophila embryonic muscle development, multiple nuclei transition from being clustered together, to splitting into two smaller clusters, to spreading along the myotube's length. Perturbations o...

  • publication . Article . 2020
    Open Access
    Authors:
    Alexandra Brito; Patrícia M. R. Pereira; Diana Soares da Costa; Rui L. Reis; Rein V. Ulijn; Jason S. Lewis; Ricardo A. Pires; Iva Pashkuleva;
    Publisher: Royal Society of Chemistry (RSC)
    Project: EC | THE DISCOVERIES CTR (739572), WT , EC | FoReCaST (668983), NIH | MOUSE GENETICS (2P30CA008748-43)

    We report on aromatic N-glucosides that inhibit selectively the cancer metabolism via two coexistent mechanisms: by initial deprivation of the glucose uptake through competitive binding in the glucose binding pocket of GLUT1 and by formation of a sequestering nanoscale ...

6 research outcomes, page 1 of 1
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