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54 research outcomes, page 1 of 6
  • publication . Other literature type . Article . 2016
    Open Access
    Authors:
    Caterina MARCHIO';
    Publisher: Springer Science and Business Media LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Triple-negative breast cancers (TNBCs), defined by lack of expression of estrogen receptor, progesterone receptor and HER2, account for 12–17% of breast cancers and are clinically perceived as a discrete breast cancer subgroup. Nonetheless, TNBC has been shown to consti...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Elio Riboli; Karina Dalsgaard Sørensen; rosario tumino; Giovanna Tagliabue;
    Publisher: Oxford University Press
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Improving prostate cancer... (5R01CA175491-04), NIH | Prospective validation of... (5R01CA160816-02), RCUK | Health of vegetarians (MR/M012190/1)

    <p>BACKGROUND: Microseminoprotein-beta (MSP), a protein secreted by the prostate epithelium, may have a protective role in the development of prostate cancer. The only previous prospective study found a 2% reduced prostate cancer risk per unit increase in MSP. This work...

  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Lorenzo Mannelli; Giuseppe Corrias;
    Publisher: Springer Science and Business Media LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Abstract Background Cancer patients often have a history of chemotherapy, putting them at increased risk of liver toxicity and pancytopenia, leading to elevated liver fat and elevated liver iron respectively. T1-in-and-out-of-phase, the conventional MR technique for liv...

  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Alison P. Klein; Brian M. Wolpin; Harvey A. Risch; Rachael Z. Stolzenberg-Solomon; Evelina Mocci; Mingfeng Zhang; Federico Canzian; Erica J. Childs; Jason W. Hoskins; Ashley Jermusyk; ...
    Publisher: Springer Science and Business Media LLC
    Project: NIH | Womens Health Study: Cont... (1R01HL080467-01), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Vitamin D, Related Genes ... (2R01CA098661-06A2), NIH | Experimental Pathology (5P30CA016087-32), NIH | Pancreatic Cancer Genetic... (5R01CA097075-05), NIH | TRIAL OF ASPIRIN AND VITA... (5R01HL043851-08), NIH | PANCREATIC CANCER CASE CO... (3R01CA059706-01A1S1), NIH | Cancer Epidemiology Cohor... (5UM1CA167552-02), NIH | CALIFORNIA COORDINATED CA... (1U58DP003862-01), NIH | The Womens Health Study: ... (1RC1HL099355-01),...

    In 2020, 146,063 deaths due to pancreatic cancer are estimated to occur in Europe and the United States combined. To identify common susceptibility alleles, we performed the largest pancreatic cancer GWAS to date, including 9040 patients and 12,496 controls of European ...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Alice Avancini; Giulia Sartori; Anastasios Gkountakos; Miriam Casali; Ilaria Trestini; Daniela Tregnago; Emilio Bria; Lee W. Jones; Michele Milella; Massimo Lanza; ...
    Publisher: John Wiley & Sons, Inc.
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Abstract Lung cancer remains the leading cause of cancer‐related death worldwide. Affected patients frequently experience debilitating disease‐related symptoms, including dyspnea, cough, fatigue, anxiety, depression, insomnia, and pain, despite the progresses achieved i...

  • publication . Article . 2014
    Open Access
    Authors:
    Jolanta Lissowska; Carlotta Sacerdote; Fredrick Schumacher; Christine Friedenreich; Maxine Chen; Sara Olson; Veronica Setiawan; Marta Crous-Bou; Irene Orlow;
    Publisher: Public Library of Science (PLoS)
    Project: NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | GENETIC SUSCEPTIBILITY TO... (5R01CA082838-04), NIH | Genome-Wide Association S... (5R01CA134958-02), NIH | Genetic Variation in Estr... (5R03CA128008-02), NIH | Molecular Epidemiology of... (1R01CA105212-01A1), NIH | Training Program in Cance... (5T32CA009001-38), NIH | DIET, HORMONES AND RISK O... (3P01CA087969-03S1), CIHR , NIH | RESEARCH IN CANCER EPIDEM... (3R35CA039779-09S1),...

    Endometrial cancer (EC) contributes substantially to total burden of cancer morbidity and mortality in the United States. Family history is a known risk factor for EC, thus genetic factors may play a role in EC pathogenesis. Three previous genome-wide association studie...

  • publication . Article . 2017
    Open Access
    Authors:
    Elliott Brea; Patrizia Mondello;
    Publisher: American Society of Hematology
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MSKCC Pilot Center for Pr... (5U54OD020355-04)

    <jats:title>Abstract</jats:title> <jats:p>Oncogenic co-operation between c-Myc and activated phosphoinositide 3-kinase (PI3K) signaling pathways is crucial in lymphomagenesis, providing an opportunity for developing mechanism-based therapy to disrupt this co-operative s...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Ajay Gopal; Martin Hutchings; Ranjana Advani; PIER LUIGI ZINZANI;
    Publisher: HAL CCSD
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Biostatistics and Bioinfo... (2P50CA097274-06)

    International audience; In recent years, the number of approved and investigational agents that can be safely administered for the treatment of lymphoma patients for a prolonged period of time has substantially increased. Many of these novel agents are evaluated in earl...

  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Bick, Ulrich; Trimboli, Rubina M; Athanasiou, Alexandra; Balleyguier, Corinne; Baltzer, Pascal AT; Bernathova, Maria; Borbély, Krisztina; Brkljacic, Boris; Carbonaro, Luca A; Clauser, Paola; ...
    Publisher: Springer Berlin Heidelberg
    Project: NWO | XCiDE: Crossing the Combu... (2300153186), NIH | MOUSE GENETICS (2P30CA008748-43), EC | HYPMED (667211), EC | CANCER SCAN (828978)

    We summarise here the information to be provided to women and referring physicians about percutaneous breast biopsy and lesion localisation under imaging guidance. After explaining why a preoperative diagnosis with a percutaneous biopsy is preferred to surgical biopsy, ...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Ilaria Alborelli; BRUNA SCAGGIANTE; Nicola Aceto;
    Publisher: Nature Publishing Group UK
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NHMRC | Client centred palliative... (425568), SNSF | Topology of intracellular... (3100-008748), SNSF | The genomic analysis of c... (310030_138513)

    Abstract Pre-symptomatic screening of genetic alterations might help identify subpopulations of individuals that could enter into early access prevention programs. Since liquid biopsy is minimally invasive it can be used for longitudinal studies in healthy volunteers to...

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