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15 research outcomes, page 1 of 2
  • publication . Article . 2018
    Open Access English
    Authors:
    Stolnicu, Simona; Hoang, Lien; Hanko-Bauer, Orsolya; Barsan, Iulia; Terinte, Cristina; Pesci, Anna; Aviel-Ronen, Sarit; Kiyokawa, Takako; Alvarado-Cabrero, Isabel; Oliva, Esther; ...
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Although 2014 World Health Organization criteria require unequivocal glandular and squamous differentiation for a diagnosis of cervical adenosquamous carcinoma, in practice, adenosquamous carcinoma diagnoses are often made in tumors that lack unequivocal squamous and/or...

  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Quintin Lee; Matthew P. Padula; Natalia Pinello; Simon H. Williams; Matthew B. O'Rourke; Marcilio Jorge Fumagalli; Joseph D. Orkin; Renhua Song; Babak Shaban; Ori Brenner; ...
    Publisher: Public Library of Science (PLoS)
    Project: NIH | Diagnostic and Prognostic... (1U19AI109761-01), NIH | MOUSE GENETICS (2P30CA008748-43)

    [Abstract] Mouse kidney parvovirus (MKPV) is a member of the provisional genus Chapparvovirus that causes renal disease in immune-compromised mice, with a disease course reminiscent of polyomavirus-associated nephropathy in immune-suppressed kidney transplant patients. ...

  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Ranjana Advani; Irene Biasoli;
    Publisher: Ferrata Storti Foundation (Haematologica)
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    This analysis explored factors influencing survival of patients with primary refractory and relapsed peripheral T-cell lymphomas enrolled in the prospective International T-cell Project. We analyzed data from 1020 patients with newly diagnosed disease, enrolled between ...

  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Josef Leibold; Daniel A Heller; Darren Johnson; Rajasekhar Vinagolu; Daniel Roxbury; Mehtap Işık; Januka Budhathoki-Uprety;
    Publisher: Springer Science and Business Media LLC
    Project: NIH | PROTEOLYTIC CONTROL OF ON... (2P01CA013106-31), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Transient Metabolite Dete... (1DP2HD075698-01)

    Development of targeted nanoparticle drug carriers often requires complex synthetic schemes involving both supramolecular self-assembly and chemical modification. These processes are generally difficult to predict, execute, and control. We describe herein a targeted dru...

  • publication . Article . Other literature type . 2015
    Open Access
    Authors:
    Aaron Viny; Barbara Spitzer; Martin A. Rivas; Cem Meydan;
    Publisher: Rockefeller University Press
    Project: NIH | Chemical Modulation of Ch... (1K99CA190861-01), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Clinical Scholars Biomedi... (5T32CA009512-27)

    Viny et al. show that depletion of the cohesin subunit Smc3 affects HSC function through disruption of chromatin structure and that cohesin haploinsufficiency cooperates with Flt3-ITD to induce transformation of stem/progenitor cells and leukemia development.

  • publication . Other literature type . Article . 2017
    Open Access
    Authors:
    Joseph Neglia; Wendy Leisenring;
    Publisher: Springer Science and Business Media LLC
    Project: NIH | Survivorship: Mentoring a... (5K05CA160724-05), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | CANCER CENTER SUPPORT GRA... (5P30CA021765-12), NIH | EMPOWER Study: Promoting ... (5R01CA134722-05), NIH | Prediction Model: Breast ... (5R01CA136783-02), NIH | CHILDHOOD CANCER SURVIVOR... (5U24CA055727-08)

    Background: The relationship between hormone exposure and breast cancer risk in women treated with chest radiotherapy for childhood cancer is uncertain. Methods: Participants included 1108 females from the Childhood Cancer Survivor Study who were diagnosed with childhoo...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Andrea Ventura; Jian Zheng;
    Publisher: Public Library of Science (PLoS)
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    BACKGROUND: Hepatocellular adenomas (HCA) are benign liver tumors that may transform into hepatocellular carcinoma (HCC), but the molecular drivers of this transformation remain ill-defined. This study evaluates the molecular changes in HCA and HCC and in comparison to ...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Professor Rosalind Eeles; Nicola Nicolai; Elizabeth Bancroft; Marta Cardoso; Lidia Feliubadalo; Manuel R. Teixeira; Gareth Evans; Judith Offman;
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | RATIONAL DESIGN OF PROSTA... (5P50CA092629-10)

    Background: Mutations in BRCA2 cause a higher risk of early-onset aggressive prostate cancer (PrCa). The IMPACT study is evaluating targeted PrCa screening using prostate-specific-antigen (PSA) in men with germline BRCA1/2 mutations. Objective: To report the utility of ...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Jonathan Coleman; Jaya Prakash;
    Publisher: Ivyspring International Publisher
    Project: EC | BERTI (605162), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MRI-Photoacoustic-Raman N... (1R01EB017748-01A1)

    Objective: Monitoring emerging vascular-targeted photodynamic therapy (VTP) and understanding the time-dynamics of treatment effects remains challenging. We interrogated whether handheld multispectral optoacoustic tomography (MSOT) could noninvasively monitor the effect...

  • publication . Article . 2018
    Open Access English
    Authors:
    Vigdis Stefansdottir; Diana M Eccles; Elena Castro; Professor Rosalind Eeles; Nicola Nicolai; Hans Vasen; Elizabeth Bancroft; Jan Lubinski; Lidia Feliubadalo; Manuel R. Teixeira; ...
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Background: Prostate-specific antigen (PSA) and PSA-velocity (PSAV) have been used to identify men at risk of prostate cancer (PrCa). The IMPACT study is evaluating PSA screening in men with a known genetic predisposition to PrCa due to BRCA1/2 mutations. This analysis ...

15 research outcomes, page 1 of 2
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