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34 research outcomes, page 1 of 4
  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    GIUSEPPE PETRALIA; David Collins; Giuseppe PETRALIA; STEFANO FANTI; Dow-Mu Koh;
    Publisher: European Association of Urology. Published by Elsevier B.V.
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Context Comparative reviews of whole-body magnetic resonance imaging (WB-MRI) and positron emission tomography/computed tomography (CT; with different radiotracers) have shown that metastasis detection in advanced cancers is more accurate than with currently used CT and...

  • publication . Article . 2016
    Open Access English
    Authors:
    Michael Hoffmeister; Richard Hayes; Bette Caan; Fredrick Schumacher; Tabitha Harrison; Stephanie Bien; Sébastien KÜRY; Mark Jenkins; Hermann Brenner;
    Publisher: Public Library of Science
    Project: NIH | Cancer Prevention Trainin... (5R25CA094880-12), NIH | Hormones and Colon Cancer... (5R01CA076366-07), NIH | Ontario Registry for Stud... (3U01CA074783-09S2), NIH | Cancer Epidemiology Cohor... (5UM1CA167552-02), NIH | A Whole Genome Admixture ... (3R01CA063464-09S1), NIH | EPIDEMIOLOGIC STUDIES OF ... (5P01CA033619-05), NIH | DIET, HORMONES AND RISK O... (3P01CA087969-03S1), NIH | AROMATIC AMINES AND COLON... (5R01CA060987-03), NIH | NUTRITIONAL AND BIOCHEMIC... (5R01CA042182-09), NIH | AUSTRALASIAN COLORECTAL C... (5U01CA097735-05),...

    Genome-wide association studies (GWAS) have identified many common single nucleotide polymorphisms (SNPs) associated with colorectal cancer risk. These SNPs may tag correlated variants with biological importance. Fine-mapping around GWAS loci can facilitate detection of...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Michal Neeman; Willem Mulder; Carlos Pérez-Medina; Jun Tang; Menno de Winther; Max Senders; francois fay; Thomas Reiner; Nicole van der Wel;
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Nanoparticles for Molecul... (9R01EB009638-05A2), NWO | EFFECT Exploiting Filtere... (2300149327), NIH | PET/MRI to study nanother... (1R01HL125703-01), NIH | Anti-inflammatory nanopar... (1R01HL118440-01A1), EC | NANOATHERO (309820)

    Hyaluronan is a biologically active polymer, which can be formulated into nanoparticles. In our study, we aimed to probe atherosclerosis-associated inflammation by using hyaluronan nanoparticles and to determine whether they can ameliorate atherosclerosis. Hyaluronan na...

  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    Leithner, Doris; Horvat, Joao V.; Bernard-Davila, Blanca; Helbich, Thomas H.; Ochoa-Albiztegui, R. Elena; Martinez, Danny F.; Zhang, Michelle; Thakur, Sunitha B.; Wengert, Georg J.; Staudenherz, Anton; ...
    Publisher: Springer Science and Business Media LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), EC | HYPMED (667211)

    PURPOSE To develop a multiparametric [18F]FDG positron emission tomography/magnetic resonance imaging (PET/MRI) model for breast cancer diagnosis incorporating imaging biomarkers of breast tumors and contralateral healthy breast tissue. METHODS In this prospective study...

  • publication . Other literature type . Article . 2016
    Open Access English
    Authors:
    Estrid Høgdall; Allan Jensen; Usha Menon;
    Project: NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN055424-007), NIH | SURVEILLANCE, EPIDEMIOLOG... (N01PC067001-001), NIH | Epidemiology of Ovarian C... (5R01CA087538-02), NIH | Steroid Hormone Genes and... (5R01CA112523-03), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MHC-Restricted and MHC-No... (1P50CA159981-01A1), NIH | Identifying Ovarian Cance... (1R01CA141154-01A2), NIH | The Progesterone Receptor... (1R03CA113148-01), NIH | Genes, Hormones &Environm... (5R01CA054419-14), NIH | University of Michigan Co... (3P30CA046592-20S2),...

    OBJECTIVE: To describe the association between postmenopausal estrogen-only therapy use and risk of ovarian carcinoma, specifically with regard to disease histotype and duration and timing of use. METHODS: We conducted a pooled analysis of 906 women with ovarian carcino...

  • publication . Other literature type . Article . 2016
    Open Access English
    Authors:
    Shuji Ogino; Richard Hayes; Michael Hoffmeister; Fredrick Schumacher; Tabitha Harrison; Bette Caan; Mark Jenkins; Hermann Brenner;
    Publisher: The University of North Carolina at Chapel Hill University Libraries
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | A Whole Genome Admixture ... (3R01CA063464-09S1), NIH | Cancer Prevention Trainin... (5R25CA094880-12), NIH | GENETIC EPIDEMIOLOGIC STU... (5R01CA059045-04), NIH | Molecular pathological ep... (2U01CA137088-05), NIH | EPIDEMIOLOGIC STUDIES OF ... (5P01CA033619-05), WT , NIH | DIET, HORMONES AND RISK O... (3P01CA087969-03S1), NIH | Ontario Registry for Stud... (3U01CA074783-09S2), NIH | AUSTRALASIAN COLORECTAL C... (5U01CA097735-05),...

    BACKGROUND: Menopausal hormone therapy (MHT) use has been consistently associated with a decreased risk of colorectal cancer (CRC) in women. Our aim was to use a genome-wide gene-environment interaction analysis to identify genetic modifiers of CRC risk associated with ...

  • publication . Article . Other literature type . Preprint . 2017
    Open Access
    Authors:
    Hauser, Kevin; Negron, Christopher; Albanese, Steven K.; Ray, Soumya; Steinbrecher, Thomas; Abel, Robert; Chodera, John D.; Wang, Lingle;
    Publisher: Springer Science and Business Media LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | The role of reorganizatio... (5R01GM121505-02)

    The therapeutic effect of targeted kinase inhibitors can be significantly reduced by intrinsic or acquired resistance mutations that modulate the affinity of the drug for the kinase. In cancer, the majority of missense mutations are rare, making it difficult to predict ...

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Pascal Guenel; bernard peissel; mikael eriksson; Thilo Dörk; Anna Jakubowska; Anna Marie Mulligan; Paolo Radice; Sara Olson; Peter Kraft; Florian Heitz; ...
    Project: NIH | Long Term Multidisciplina... (5UM1CA186107-05), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Cancer Epidemiology Cohor... (5UM1CA167552-02), NHMRC | Translation of PALB2 gene... (1029974), NHMRC | Personalized clinical gen... (1061177), NIH | MHC-Restricted and MHC-No... (1P50CA159981-01A1), NIH | OVARIAN CANCER RISK AND S... (5K07CA080668-06), WT | Understanding the genetic... (090532), NIH | DIET, HORMONES AND RISK O... (3P01CA087969-03S1), EC | COGS (223175),...

    <p style="-webkit-font-smoothing: antialiased; box-sizing: border-box; margin: 0px auto 10px; line-height: 2.5rem;"><strong style="-webkit-font-smoothing: antialiased; box-sizing: border-box;">Background:</strong> The rarity of mutations in <em style="-webkit-font-smoot...

  • publication . Article . Other literature type . 2015
    Open Access
    Authors:
    Bruno Costa-Silva; Tang-Long Shen; Angela Di Giannatale; Sophia Ceder; Hector Peinado; Rajasekhar Vinagolu;
    Publisher: eScholarship, University of California
    Project: NIH | Characterization and Func... (1U01CA169538-01), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Exosome-mediated Transfer... (5R01CA169416-03)

    © 2015 Macmillan Publishers Limited. All rights reserved. Ever since Stephen Paget's 1889 hypothesis, metastatic organotropism has remained one of cancer's greatest mysteries. Here we demonstrate that exosomes from mouse and human lung-, liver- and brain-tropic tumour c...

  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Henning Reis;
    Publisher: Springer Science and Business Media LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), EC | MELGEN (641458)

    Background Conjunctival melanoma is a potentially deadly eye tumour. Despite effective local therapies, tumour recurrence and metastasis remain frequent. The genetics of conjunctival melanomas remain incompletely understood. Methods A large cohort of 63 conjunctival mel...

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