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4 research outcomes, page 1 of 1
  • publication . Other literature type . Article . 2020
    Open Access
    Authors:
    Valentina Fossati; Anna Rodina; Mark Dunphy; Wenjie Luo; Maria Carmen Inda; Maria Carmen Inda; Sonia Sequeira; Thomas A. Neubert; Natalia V. De Marco García; Afsar Barlas; ...
    Publisher: Springer Science and Business Media LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | LTQ-Orbitrap Mass Spectro... (1S10RR027990-01A1), NIH | Cell and molecular pathob... (3P01AG017617-07S1), NIH | Biomarkers for predicting... (5R01CA172546-05), NIH | The role of Hsp 90 in Alz... (5K01AG032364-05), NIH | MSKCC Pilot Center for Pr... (5U54OD020355-04), NIH | Small molecule Hsp90 inhi... (5U01AG032969-04), NIH | Cellular and Molecular Me... (7R01AG043375-03), NIH | A chemical chaperomics pl... (1R56AG061869-01), NIH | CORE--STATISTICS AND DATA... (1P01AG014449-02)

    Optimal functioning of neuronal networks is critical to the complex cognitive processes of memory and executive function that deteriorate in Alzheimer’s disease (AD). Here we use cellular and animal models as well as human biospecimens to show that AD-related stressors ...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Timothy Vartanian; Jennifer R. Linden; Eric F. Schmidt; Marissa Valenzuela; Francisco A. Uzal; Claudia Flores; Adam O Michel; Sebastian Dobrow;
    Publisher: Public Library of Science
    Project: NIH | Profiling axonal RNA in v... (1R21NS105047-01A1), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Molecular phenotyping of ... (5R01NS091722-03)

    Clostridium perfringens epsilon toxin (ETX) is responsible for causing the economically devastating disease, enterotoxaemia, in livestock. It is well accepted that ETX causes blood brain barrier (BBB) permeability, however the mechanisms involved in this process are not...

  • publication . Other literature type . Article . 2017
    Open Access
    Authors:
    Kristen M. Cunanan; Amber L. Simpson; Mithat Gonen; Richard K. G. Do; Maeve A. Lowery; Jayasree Chakraborty; Eileen M. O’Reilly; Joanna G. Escalon; Liana Langdon-Embry; Peter J. Allen;
    Publisher: Public Library of Science (PLoS)
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers in the United States with a five-year survival rate of 7.2% for all stages. Although surgical resection is the only curative treatment, currently we are unable to differentiate between resectable ...

  • publication . Article . 2017
    Open Access English
    Authors:
    Vaios Hatzoglou; Andrei I. Holodny; Antonio Omuro; Alpesh Mehta; Mariza Daras; Kathryn Beal; Jamie Tisnado; Kyung K. Peck;
    Publisher: John Wiley and Sons Inc.
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Abstract Brain metastases originating from different primary sites overlap in appearance and are difficult to differentiate with conventional MRI. Dynamic contrast‐enhanced (DCE)‐MRI can assess tumor microvasculature and has demonstrated utility in characterizing primar...

4 research outcomes, page 1 of 1