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  • publication . Article . Other literature type . 2015
    Tumour exosome integrins determine organotropic metastasis
    Open Access
    Authors:
    Tari A. King; Angela Di Giannatale; Maneesh Jain; Bruno Costa-Silva; Paul M. Grandgenett; Ayuko Hoshino; Leonard H. Wexler; Lindsay A. Pharmer; Kunihiro Uryu; Mina J. Bissell; ...
    doi: 10.1038/nature15756
    pmc: PMC4788391
    pmid: 26524530
    Publisher: eScholarship, University of California
    Project: NIH | Characterization and Func... (1U01CA169538-01), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Exosome-mediated Transfer... (5R01CA169416-03)

    © 2015 Macmillan Publishers Limited. All rights reserved. Ever since Stephen Paget's 1889 hypothesis, metastatic organotropism has remained one of cancer's greatest mysteries. Here we demonstrate that exosomes from mouse and human lung-, liver- and brain-tropic tumour c...

1 research outcomes, page 1 of 1