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884 research outcomes, page 1 of 89
  • publication . Other literature type . Article . 2016
    Open Access
    Authors:
    Jason Lewis; Nerissa Viola; Linden Wyatt; Mirkka P Sarparanta;
    Publisher: American Chemical Society (ACS)
    Project: NIH | pHLIP-based agents for pr... (1F32CA186721-01A1), NIH | Shared Instrument: Focus ... (1S10RR020892-01), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | PET Imaging of Cancer wit... (5R01CA138468-04), NIH | The Ivis Spectrum CT for ... (1S10OD016207-01), AKA | New radiolabeled molecula... (278056)

    pH (low) insertion peptides (pHLIP peptides) target acidic extracellular environments in vivo due to pH-dependent cellular membrane insertion. Two variants (Var3 and Var7) and wild-type (WT) pHLIP peptides have shown promise for in vivo imaging of breast cancer. Two pos...

  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Li, Qiongge; Ferraro, Gino Del; Pasquini, Luca; Peck, Kyung K.; Makse, Hernán A.; Holodny, Andrei I.;
    Publisher: MIT Press
    Project: NIH | Developmental Core (5U54CA132378-03), NIH | MOUSE GENETICS (2P30CA008748-43), NSF | CRCNS: Targeted Stimulati... (1515022), NIH | Planning and Evaluation (5U54CA137788-03), NIH | Supplement: Network Metho... (3R01EB022720-03S1)

    Functional magnetic resonance imaging (fMRI) is widely used in clinical applications to highlight brain areas involved in specific cognitive processes. Brain impairments, such as tumors, suppress the fMRI activation of the anatomical areas they invade and, thus, brain-d...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Murray, Katie S.; Liu, Nick W.; Russo, Paul;
    Publisher: Elsevier
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)
  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Shuji Ogino; Brendan Guercio; Donna Niedzwiecki;
    Publisher: Public Library of Science (PLoS)
    Project: NIH | Multidisciplinary Trainin... (5T32HL125232-02), NIH | NCTN Lead Academic Partic... (5U10CA180867-04), NIH | Alliance for Clinical Tri... (3U10CA180821-02S2), NIH | Network Lead Academic Par... (3U10CA180791-04S1), NIH | Accelerating Transdiscipl... (5R35CA197735-04), NIH | Statistics and Data Cente... (5U10CA180882-02), NIH | CANCER AND LEUKEMIA GROUP... (5U10CA060138-04), NIH | Southeast Clinical Oncolo... (5UG1CA189858-02), NIH | Role of Vitamin D, Inflam... (5K07CA148894-02), NIH | ECOG-ACRIN Operations Cen... (3U10CA180820-02S3),...

    Purpose Observational studies have demonstrated increased colon cancer recurrence and mortality in states of excess energy balance, as denoted by factors including sedentary lifestyle, diabetes, increased dietary glycemic load, and increased intake of sugar-sweetened be...

  • publication . Article . 2017
    Open Access
    Authors:
    Nori, Priya; Madaline, Theresa; Munjal, Iona; Bhar, Shubha; Guo, Yi; Seo, Susan K.; Porrovecchio, Andrea; Gancher, Elizabeth; Nosanchuk, Joshua; Pirofski, Liise-anne; ...
    Publisher: Oxford University Press (OUP)
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>To impart principles of antimicrobial stewardship (AS) and infection prevention and control (IPC), we developed a curriculum tailored to the diverse aptitudes of learners at our med...

  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    Jessica Vincent; Carolina Adura; Pu Gao; Antonio Luz; Lodoe Lama; Yasutomi Asano; Rei Okamoto; Toshihiro Imaeda; Jumpei Aida; Katherine Rothamel; ...
    Publisher: Springer Science and Business Media LLC
    Project: NIH | Posttranscriptional regul... (5R01GM104962-02), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Chemistry Biology Interfa... (4T32GM065086-14), NIH | Deciphering Post-transcri... (1R35GM119569-01), NIH | NE-CAT Center for Advance... (4P41GM103403-14)

    Upon DNA binding cyclic GMP-AMP synthase (cGAS) produces a cyclic dinucleotide, which leads to the upregulation of inflammatory genes. Here the authors develop small molecule cGAS inhibitors, functionally characterize them and present the inhibitor and DNA bound cGAS cr...

  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Hemant Suryawanshi; Pavel Morozov; Alexander Straus; Nicole Sahasrabudhe; Klaas E. A. Max; Aitor Garzia; Manjunath Kustagi; Thomas Tuschl; Zev Williams;
    Publisher: American Association for the Advancement of Science (AAAS)
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Placenta-derived extracel... (7R01HD086327-03), NIH | Biochemical and structura... (5U19CA179564-02)

    Single-cell transcriptomics reveal cellular diversity in the human first-trimester placenta and decidua.

  • publication . Article . 2016
    Open Access English
    Authors:
    Lawrence Dauer;
    Publisher: BioMed Central
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    Background Whole body fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) is the standard of care in oncologic diagnosis and staging, and patient radiation dose must be well understood to balance exam benefits with the risk from radi...

  • publication . Preprint . 2020
    Open Access English
    Authors:
    Kose, Kivanc; Bozkurt, Alican; Alessi-Fox, Christi; Gill, Melissa; Longo, Caterina; Pellacani, Giovanni; Dy, Jennifer; Brooks, Dana H.; Rajadhyaksha, Milind;
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Automated Image Guidance ... (5R01CA199673-02)

    In-vivo optical microscopy is advancing into routine clinical practice for non-invasively guiding diagnosis and treatment of cancer and other diseases, and thus beginning to reduce the need for traditional biopsy. However, reading and analysis of the optical microscopic...

  • publication . Article . 2018
    Open Access
    Authors:
    Tollinche, Luis; Jackson, Jacob; La, Melvin; Desiderio, Dawn; Yeoh, Cindy;
    Publisher: Scitechnol Biosoft Pvt. Ltd.
    Project: NIH | MOUSE GENETICS (2P30CA008748-43)

    We report a case in which a radial arterial line was placed prior to induction of general anaesthesia in a 76 year old male with prostate cancer and multiple co-morbidities who presented for thoracoscopic resection of a right lower lobe carcinoid lung tumor. The patient...

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