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109 research outcomes, page 1 of 11
  • publication . Article . 2018
    Open Access
    Authors:
    Schmitz, Gerd; Orsó, Evelyn;
    Publisher: Springer Nature
    Project: EC | LIPIDOMICNET (202272)

    Lipoprotein (a) [Lp(a)] is a modified LDL particle with an additional apolipoprotein [apo(a)] protein covalently attached by a thioester bond. Multiple isoforms of apo(a) exist that are genetically determined by differences in the number of Kringle-IV type-2 repeats enc...

  • publication . Article . Other literature type . 2011
    Open Access
    Authors:
    Challa, T. D.; Beaton, N.; Arnold, M.; Rudofsky, G.; Langhans, W.; Wolfrum, C.;
    Publisher: American Society for Biochemistry & Molecular Biology (ASBMB)
    Project: EC | LIPIDOMICNET (202272), EC | ADIPODIF (205641)

    Increased nutrient intake leads to excessive adipose tissue accumulation, obesity, and the development of associated metabolic disorders. How the intestine signals to adipose tissue to adapt to increased nutrient intake, however, is still not completely understood. We s...

  • publication . Article . 2013
    Open Access English
    Authors:
    Stegmaier, Philip; Kel, Alexander; Wingender, Edgar; Borlak, Jürgen;
    Publisher: PUBLIC LIBRARY SCIENCE
    Project: EC | LIPIDOMICNET (202272)

    Algorithmic comparison of DNA sequence motifs is a problem in bioinformatics that has received increased attention during the last years. Its main applications concern characterization of potentially novel motifs and clustering of a motif collection in order to remove r...

  • publication . Article . Review . 2010
    Open Access English
    Authors:
    Briand, Nolwenn; Dugail, Isabelle; Le Lay, Soazig;
    Publisher: HAL CCSD
    Project: EC | LIPIDOMICNET (202272)

    International audience; <p>Caveolae are specialized lipid microdomains, forming small invaginations in the plasma membrane, known to be implicated in multiple functions including lipid storage, cell signaling and endocytosis. Formation of these wide flask-shaped invagin...

  • publication . Other literature type . Article . 2009
    Open Access English
    Authors:
    Chen, Chia-Ching; Yamada, Tetsuji; Chiu, I-Ming; Liu, Yi-Kuen;
    Publisher: Molecular Diversity Preservation International
    Project: EC | LIPIDOMICNET (202272)

    This paper examines the effectiveness of Taiwanese environmental health policies, whose aim is to improve environmental quality by reducing tire waste via the Tire Resource Recovery Program. The results confirm that implemented environmental health policies improve the ...

  • publication . Article . Other literature type . 2014
    Open Access English
    Authors:
    Dönitz, Jürgen; Wingender, Edgar;
    Project: EC | LIPIDOMICNET (202272)

    Background In multicellular organisms, an intercellular signaling network communicates information from the environment or distant tissues to defined target cells. Intercellular signaling (mostly mediated by hormones) can affect the metabolic state and the gene expressi...

  • publication . Article . 2017
    Open Access English
    Authors:
    Katarzyna D. Sluzalska; Gerhard Liebisch; Jochen Wilhelm; Bernd Ishaque; Holger Hackstein; Gerd Schmitz; Markus Rickert; Juergen Steinmeyer;
    Publisher: Nature Publishing Group
    Project: EC | LIPIDOMICNET (202272)

    Abstract Elevated levels of growth factors and phospholipids (PLs) have been found in osteoarthritic synovial fluid (SF), although the metabolic regulation of PLs is currently unknown. This study aimed to determine the effects of growth factors on the biosynthesis of PL...

  • publication . Article . Other literature type . 2013
    Open Access English
    Authors:
    Foster, Joseph M.; Moreno, Pablo; Fabregat, Antonio; Hermjakob, Henning; Steinbeck, Christoph; Apweiler, Rolf; Wakelam, Michael J. O.; Vizcaíno, Juan Antonio;
    Publisher: PUBLIC LIBRARY SCIENCE
    Project: EC | PROTEOMEXCHANGE (260558), EC | LIPIDOMICNET (202272), WT | The Proteomics Identifica... (085949)

    Protein sequence databases are the pillar upon which modern proteomics is supported, representing a stable reference space of predicted and validated proteins. One example of such resources is UniProt, enriched with both expertly curated and automatic annotations. Taken...

  • publication . Article . 2014
    Open Access
    Authors:
    Radner, Franz P.W.; Grond, Susanne; Lass, Achim; Zechner, Rudolf;
    Publisher: Informa UK Limited
    Project: EC | LIPIDOMICNET (202272)

    Keratinocyte differentiation is essential for skin development and the formation of the skin permeability barrier. This process involves an orchestrated remodelling of lipids. The cleavage of precursor lipids from lamellar bodies by β-glucocerebrosidase, sphingomyelinas...

  • publication . Article . 2012
    Open Access English
    Authors:
    Bourez, Sophie; Le Lay, Soazig; Van den Daelen, Carine; Louis, Caroline; Larondelle, Yvan; Thomé, Jean-Pierre; Schneider, Yves-Jacques; Dugail, Isabelle; Debier, Cathy;
    Publisher: Public Library of Science
    Project: EC | LIPIDOMICNET (202272)

    BACKGROUND: Polychlorinated biphenyls (PCBs) are persistent environmental pollutants that preferentially accumulate in lipid-rich tissues of contaminated organisms. Although the adipose tissue constitutes a major intern reservoir of PCBs and recent epidemiological studi...

109 research outcomes, page 1 of 11
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