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274 research outcomes, page 1 of 28
  • publication . Other literature type . Article . 2014
    Open Access English
    Authors:
    Iman Elfeddali; C.M. van der Feltz-Cornelis; J. van Os; Susanne Knappe; Eduard Vieta; Hans-Ulrich Wittchen; Carla Obradors-Tarragó; Josep Maria Haro;
    Persistent Identifiers
    Publisher: Multidisciplinary Digital Publishing Institute
    Project: EC | ROAMER (282586)

    with a high probability of success, given that Europe has important strengths, such as skilled academics and a long research history. Finally, the experts stressed the importance of creating funding and coordinated networking as essential action needed in order to targe...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Xin Song; Adam G. Tabák; Björn Zethelius; John S Yudkin; Stefan Söderberg; Tiina Laatikainen; Coen D.A. Stehouwer; Rachel Dankner; Pekka Jousilahti; Altan Onat; ...
    Persistent Identifiers
    Publisher: BioMed Central
    Project: EC | E-PREDICE (279074)

    Background To estimate cardiovascular disease (CVD) mortality in relation to obesity and gender. Methods Data from 11 prospective cohorts from four European countries including 23 629 men and 21 965 women, aged 24 to 99 years, with a median follow-up of 7.9 years were a...

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  • publication . Article . 2013
    Open Access English
    Authors:
    Tatyana Y. Doktorova; Reha Yildirimman; Mathieu Vinken; Mireia Vilardell; Tamara Vanhaecke; Hans Gmuender; Roque Bort; Gabriella Brolén; Gustav Holmgren; Ruoya Li; ...
    Persistent Identifiers
    Project: EC | DIXA (283775)

    As the conventional approach to assess the potential of a chemical to cause cancer in humans still includes the 2-year rodent carcinogenicity bioassay, development of alternative methodologies is needed. In the present study, the transcriptomics responses following expo...

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  • publication . Article . 2018
    Open Access
    Authors:
    Guy M. Goodwin; Emily A. Holmes; Erik Andersson; Michael Browning; Andrew Jones; Johanna Lass-Hennemann; Kristoffer N.T. Månsson; Carolin Moessnang; Elske Salemink; Alvaro Sanchez; ...
    Publisher: Elsevier BV
    Project: WT , EC | Farewell flashbacks (705641), UKRI | Information Bias in Depre... (MR/N008103/1)

    This ECNP meeting was designed to build bridges between different constituencies of mental illness treatment researchers from a range of backgrounds with a specific focus on enhancing the development of novel, evidence based, psychological treatments. In particular we w...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Kay Deckers; Mariagnese Barbera; Sebastian Köhler; Tiia Ngandu; Martin P.J. van Boxtel; Minna Rusanen; Tiina Laatikainen; Frans R.J. Verhey; Hilkka Soininen; Miia Kivipelto; ...
    Persistent Identifiers
    Project: AKA | Clinical trials network f... (278457), AKA | Fingerprinting the risk o... (287490), EC | VPH-DARE@IT (601055), AKA | Fingerprinting the risk o... (319318), AKA | The World Wide FINGERS (W... (317465), EC | Brain Health Toolbox (804371)

    Objective As no causal treatment for dementia is available yet, the focus of dementia research is slowly shifting towards prevention strategies. Therefore, this study aimed to examine the predictive accuracy of the "LIfestyle for BRAin Health" (LIBRA) score, a weighted ...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Liu Shi; Laura Winchester; Benjamine Y. Liu; Richard Killick; Elena M. Ribe; Sarah Westwood; Alison L. Baird; Noel J. Buckley; Shengjun Hong; Valerija Dobricic; ...
    Persistent Identifiers
    Project: EC | EMIF (115372)

    [Background]: Previous studies suggest that Dickkopf-1 (DKK1), an inhibitor of Wnt signaling, plays a role in amyloid-induced toxicity and hence Alzheimer’s disease (AD). However, the effect of DKK1 expression on protein expression, and whether such proteins are altered...

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  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Lisa Vermunt; Graciela Muniz-Terrera; Lea Ter Meulen; Colin Veal; Kaj Blennow; Archie Campbell; Isabelle Carrié; Julien Delrieu; Karine Fauria; Gema Huesa Rodríguez; ...
    Publisher: Alzheimer's research & therapy
    Project: WT | Stratifying Resilience an... (104036), EC | EPAD (115736)

    AbstractBackgroundRecruitment is often a bottleneck in secondary prevention trials in Alzheimer disease (AD). Furthermore, screen-failure rates in these trials are typically high due to relatively low prevalence of AD pathology in individuals without dementia, especiall...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Nikos Papadimitriou; Konstantinos K. Tsilidis; Philippos Orfanos; Vassiliki Benetou; Evangelia E. Ntzani; Isabelle Soerjomataram; Annemarie Künn-Nelen; Ulrika Pettersson-Kymmer; Sture Eriksson; Hermann Brenner; ...
    Persistent Identifiers
    Project: EC | CHANCES (242244)

    Source at https://doi.org/10.1016/S2468-2667(17)30046-4. Background: No studies have estimated disability-adjusted life-years (DALYs) lost due to hip fractures using real-life follow-up cohort data. We aimed to quantify the burden of disease due to incident hip fractur...

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  • publication . Article . Other literature type . 2014
    Open Access English
    Authors:
    Alexander Gusev; S. Hong Lee; Gosia Trynka; Hilary Finucane; Bjarni J. Vilhjálmsson; Han Xu; Chongzhi Zang; Stephan Ripke; Brendan Bulik-Sullivan; Eli Stahl; ...
    Publisher: The American Society of Human Genetics. Published by Elsevier Inc.
    Project: NIH | Fine-mapping heritability... (5F32GM106584-02), NIH | Statistical methods for s... (5R01MH101244-02), NHMRC | Uncoupled Research Fellow... (613602), EC | EIMS (294838), NIH | Heritability of complex t... (5R03HG006731-02), NHMRC | Estimation and partitioni... (1050218), WT | The genetics of weight, B... (076113)

    Regulatory and coding variants are known to be enriched with associations identified by genome-wide association studies (GWASs) of complex disease, but their contributions to trait heritability are currently unknown. We applied variance-component methods to imputed geno...

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  • publication . Article . Other literature type . 2010
    Open Access
    Authors:
    Stacy Steinberg; Ole Mors; Anders D. Børglum; Omar Gustafsson; Thomas Werge; Preben Bo Mortensen; Ole A. Andreassen; Engilbert Sigurdsson; Thorgeir E. Thorgeirsson; Y. Bottcher; ...
    Publisher: Springer Science and Business Media LLC
    Project: EC | PSYCHGENE (218251), EC | PSYCHCNVS (223423)

    A trio of genome-wide association studies recently reported sequence variants at three loci to be significantly associated with schizophrenia. No sequence polymorphism had been unequivocally (P5 × 10 8) associated with schizophrenia earlier. However, one variant, rs1344...

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274 research outcomes, page 1 of 28