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247,757 research outcomes, page 1 of 24,776
  • publication . Article . 2017
    Open Access
    Authors:
    Tim McLean; Carsten Saft; Harald Gelderblom; Josef Priller; Sigurd Süssmuth; Wilhelm Fischer; Rainer Hoffmann; Torsten Wüstenberg; Bernhard Landwehrmeyer; Bernhard Landwehrmeyer; ...

    <p>OBJECTIVE: To evaluate the efficacy and safety of bupropion in the treatment of apathy in Huntington's disease (HD).</p><p>METHODS: In this phase 2b multicentre, double-blind, placebo-controlled crossover trial, individuals with HD and clinical signs of apathy accord...

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  • publication . Article . 2016
    Open Access
    Authors:
    Natasa Milic; Goran Trajkovic; Dejana Stanisavljevic; Jelena Marinkovic; Aleksandar Corac; Jelena S. Milin; Marko Savic; Ivan Nikolic; Zoran Bukumiric; Andja Cirkovic; ...
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)
    Project: MESTD | Industry production of le... (37016)

    Background Although recent studies report on the benefits of blended learning in improving medical student education, there is still no empirical evidence on the relative effectiveness of blended over traditional learning approaches in medical statistics. We implemented...

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  • publication . Other literature type . Article . 2009
    Open Access
    Authors:
    Michael F. Tlusty; Andrew W. Bruckner; Andrew L. Rhyne; Andrew L. Rhyne; Randi D. Rotjan; Randi D. Rotjan;
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)

    Background Fishery management has historically been an inexact and reactionary discipline, often taking action only after a critical stock suffers overfishing or collapse. The invertebrate ornamental fishery in the State of Florida, with increasing catches over a more d...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Reena Mourya; Junbae Jee; Jorge A. Bezerra; Lin Fei; Michael Wagner; Pranavkumar Shivakumar;
    Persistent Identifiers
    Publisher: Public Library of Science
    Project: NIH | Biological Basis of Pheno... (5R01DK083781-04), NIH | Digestive Health Center: ... (3P30DK078392-03S1), NIH | Immunologic dysfunction i... (1R01DK064008-01)

    Biliary atresia is progressive fibro-inflammatory cholangiopathy of young children. Central to pathogenic mechanisms of injury is the tissue targeting by the innate and adaptive immune cells. Among these cells, neutrophils and the IL-8/Cxcl-8 signaling via its Cxcr2 rec...

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  • publication . Article . Other literature type . 2013
    Open Access
    Authors:
    Hongbin Xu; Anna Dongari-Bagtzoglou; Clarissa J. Nobile;
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)
    Project: NIH | Oral Epithelial Cells, Ca... (5R01DE013986-10)

    Candida albicans is the most common human fungal pathogen. Many organisms, including C. albicans, secrete glucanases under different environmental conditions. Here, we report a novel role for beta-1, 3- glucanase in inducing Candida albicans to form filaments at 22°C an...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Jason A. Miranda; Shannon K. McClintock; Kathryn N. Shepard; Robert C. Liu;
    Persistent Identifiers
    Publisher: Public Library of Science
    Project: NIH | Training in Systems and I... (5T32GM008605-12), NSF | Center for Behavioral Neu... (9876754), NIH | IRACDA Fellowships in Res... (5K12GM000680-17)

    Subcortical auditory nuclei were traditionally viewed as non-plastic in adulthood so that acoustic information could be stably conveyed to higher auditory areas. Studies in a variety of species, including humans, now suggest that prolonged acoustic training can drive lo...

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  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    Lee-Suk Kim; HyangHee Kim; Kyung Won Park; Ji-Hye Kim; Soo Jung Lee;
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)

    It is increasingly agreed upon that cognitive and audiological factors are associated with self-perceived hearing handicap in old adults. This study aimed to compare self-perceived hearing handicap among mild cognitive impairment (MCI) subgroups and a cognitively normal...

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  • publication . Article . 2015
    Open Access
    Authors:
    James Davis Reimer; Masaru Mizuyama; José de Anchieta C. C. Nunes; Ruy K.P. Kikuchi; Igor C. S. Cruz; Igor C. S. Cruz; Rodrigo Reis; Joel C. Creed; Tiago Albuquerque; Miguel Loiola;
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)

    Consequences of reef phase shifts on fish communities remain poorly understood. Studies on the causes, effects and consequences of phase shifts on reef fish communities have only been considered for coral-to-macroalgae shifts. Therefore, there is a large information gap...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Francis Juanes; Rodney A. Rountree; Marta Bolgan;
    Publisher: Public Library of Science

    The soundscape composition of temperate freshwater habitats is poorly understood. Our goal was to document the occurrence of biological and anthropogenic sounds in freshwater habitats over a large (46,000 km2) area along the geographic corridors of five major river syst...

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  • publication . Article . 2015
    Open Access
    Authors:
    Rafael Mañez; Cristina Costa; Magdiel Pérez-Cruz;
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)
    Project: EC | TRANSLINK (603049)

    We have previously described that boosted natural xenoantibodies in rats cross-react to bacteria by targeting carbohydrate antigens. This type of immunization is associated with reduced survival after cecal ligation and puncture (CLP). In the present study, we investiga...

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247,757 research outcomes, page 1 of 24,776