The nucleus represents a cellular compartment where the discrimination of self from non-self nucleic acids is vital. While emerging evidence establishes a nuclear non-self DNA sensing paradigm, the nuclear sensing of non-self RNA, such as that from nuclear-replicating R...

<jats:p>Parkinson’s disease (PD) is the second most common neurodegenerative disorder and is characterized by the presence of pathological intracellular aggregates primarily composed of misfolded <jats:italic>α</jats:italic>-synuclein. This pathology implicates the mole...

Comment: The 39th International Conference on Software Engineering (Companion volume) (ICSE 2017), pp. 51--54, Buenos Aires, Argentina, May, 2017

Arabidopsis FY, a homologue of the yeast RNA 3' processing factor Pfs2p, regulates the autonomous floral transition pathway through its interaction with FCA, an RNA binding protein. It is demonstrated here that FY also influences seed dormancy. Freshly-harvested seed of...

Apoptotic death of cells damaged by genotoxic stress requires regulatory input from surrounding tissues. The C. elegans scaffold protein KRI-1, ortholog of mammalian KRIT1/CCM1, permits DNA damage-induced apoptosis of cells in the germline by an unknown cell non-autonom...

Comment: Latex, 30 pages. v2: discussion in section 5 modified and improved, other minor changes, references added

Abiotic and biotic stresses limit the growth and productivity of plants. In the current global scenario, in order to meet the requirements of the ever-increasing world population, chemical pesticides and synthetic fertilizers are used to boost agricultural production. T...

In pTx MRI systems, the prediction of local SAR is based on numerical electromagnetic (EM) simulations and used to scale RF power to ensure FDA SAR limits are not exceeded. This prediction becomes more complex when superposition of E-fields from multiple coupled coils a...

Very often, models in biology, chemistry, physics, and engineering are systems of polynomial or power-law ordinary differential equations, arising from a reaction network. Such dynamical systems can be generated by many different reaction networks. On the other hand, ne...

of a non-interacting condensate of 87 Rb atoms from a potential barrier in the non-asymptotic regime, for which the collision dynamics are still ongoing. We show that for near-transparent barriers, there are two distinct transient scattering effects that arise and drama...