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271,969 research outcomes, page 1 of 27,197
  • publication . Article . 2014
    Open Access English
    Authors:
    Peter C. Amadio; Kai Nan An; Anne Gingery; Tamami Moriya; Ramona L. Reisdorf; Takako Chikenji; Chunfeng Zhao; Matthias Vanhees;
    Persistent Identifiers
    Publisher: Public Library of Science
    Project: NIH | Subsynovial Connective Ti... (5R01AR049823-06)

    Carpal tunnel syndrome (CTS) is an idiopathic disease that results from increased fibrosis of the subsynovial connective tissue (SSCT). A recent study found overexpression of both transforming growth factor-β (TGF-β) and connective tissue growth factor (CTGF) in the SSC...

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  • publication . Article . 2011
    Open Access English
    Authors:
    Ran Levy; Avraham Raz; Anat Biran; Françoise Poirier; Yoel Kloog;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: NIH | The Role of Tumor Cell Su... (5R37CA046120-22)

    International audience; BACKGROUND: Galectin-3 (Gal-3) and active (GTP-bound) K-Ras contribute to the malignant phenotype of many human tumors by increasing the rate of cell proliferation, survival, and migration. These Gal-3-mediated effects result from a selective bin...

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  • publication . Article . Preprint . Other literature type . 2017
    Open Access English
    Authors:
    Konrad P. Kording; Konrad P. Kording; Eric Jonas;
    Publisher: Public Library of Science
    Project: NSF | Making Sense at Scale wit... (1139158), NIH | SUBSYNAPTIC PROTEINS AT N... (5R01NS021579-06), NIH | Recording neural activiti... (5R01MH103910-03), NIH | The representation of unc... (5R01NS074044-04)

    Author Summary Neuroscience is held back by the fact that it is hard to evaluate if a conclusion is correct; the complexity of the systems under study and their experimental inaccessability make the assessment of algorithmic and data analytic technqiues challenging at b...

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  • publication . Other literature type . Article . 2013
    Open Access
    Authors:
    Madhuri Wadehra; Meagan Kiyohara; Lynn K. Gordon; Lee Goodglick; Jonathan Braun; Maoyong Fu; P Dhawan; Ann M. Chan;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: NIH | The Early Detection Resea... (5U24CA086366-10), NIH | Targeting EMP2 in Endomet... (5R21CA131756-02), NIH | Cancer Center Support Gra... (3P30CA016042-35S3), NIH | Using EMP2 for Image Guid... (1R01CA163971-01A1)

    Understanding tumor-induced angiogenesis is a challenging problem with important consequences for the diagnosis and treatment of cancer. In this study, we define a novel function for epithelial membrane protein-2 (EMP2) in the control of angiogenesis. EMP2 functions as ...

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  • publication . Article . 2009
    Open Access English
    Authors:
    Hoonmo L Koo; Herbert L DuPont; David B Huang;
    Publisher: Dove Medical Press
    Project: NIH | Host Genetic Susceptibili... (1K23DK084513-01)

    Hoonmo L Koo1,2, Herbert L DuPont1,2, David B Huang31Baylor College of Medicine, Houston, TX, USA; 2University of Texas at Houston School of Public Health, Houston, TX, USA; 3Veterans Affairs Medical Center, East Orange, NJ, USAAbstract: Travelers’ diarrhea is...

  • publication . Article . Part of book or chapter of book . 2010
    Open Access
    Authors:
    William J. Jusko; Richard R. Almon; Ioannis P. Androulakis; Siddharth Sukumaran; Debra C. DuBois; Meric A. Ovacik;
    Publisher: Springer Science and Business Media LLC
    Project: NIH | CORTICOSTEROID PHARMACOKI... (2R01GM024211-17)

    <p>Abstract</p> <p>Background</p> <p>Circadian rhythms are 24 hour oscillations in many behavioural, physiological, cellular and molecular processes that are controlled by an endogenous clock which is entrained to environmental factors including light, food and stress. ...

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  • publication . Article . 2012
    Open Access English
    Authors:
    Ingo Ruczinski; Rasika A. Mathias; Susan Sergeant; Wenqing Fu; Hannah C. Ainsworth; Dara G. Torgerson; Joshua M. Akey; Kathleen C. Barnes; Floyd H. Chilton;
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)
    Project: NIH | Project 3-Mechanism of Le... (5P50AT002782-02)

    Long chain polyunsaturated fatty acids (LC-PUFAs) are essential for brain structure, development, and function, and adequate dietary quantities of LC-PUFAs are thought to have been necessary for both brain expansion and the increase in brain complexity observed during m...

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  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Elliott J. Hagedorn; Madeleine L. Daily; Mauricio Cortes; Trista E. North; Trista E. North; Leonard I. Zon; Leonard I. Zon; Sarah Y. Liu; Lindsay N. Theodore; Kelsey Natsuhara; ...
    Publisher: Elsevier
    Project: NIH | Customized stem cells for... (5R24DK092760-02), NIH | A Comparative Approach To... (5R01DK053298-14), NIH | The Role of Inflammation ... (1F31HL132410-01A1), NIH | Center of Molecular Devel... (2P30DK049216-12), NIH | Metabolic regulation of h... (5R01DK098241-04)

    Summary Hematopoietic stem/progenitor cells (HSPCs) are formed during ontogeny from hemogenic endothelium in the ventral wall of the dorsal aorta (VDA). Critically, the cellular mechanism(s) allowing HSPC egress and migration to secondary niches are incompletely underst...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Wang Huiru; Rui Shao; Meijuan Fang; Yuhua Xue; Mingtao Ao; Diao Yu; Zhen Wu; Xiang Gao; Qiang Zhou; Jun Wu;
    Persistent Identifiers
    Publisher: Nature Publishing Group
    Project: NIH | Regulation of Transcripti... (5R01AI041757-07)

    Abstract The principal barrier to the eradication of HIV/AIDS is the existence of latent viral reservoirs. One strategy to overcome this barrier is to use latency-reversing agents (LRAs) to reactivate the latent proviruses, which can then be eliminated by effective anti...

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  • publication . Article . 2014
    Open Access
    Authors:
    Louis M. Mansky; Jonathan M.O. Rawson;
    Persistent Identifiers
    Publisher: MDPI AG
    Project: NIH | Minnesota Training Progra... (5T32AI083196-07), NIH | HIV Reverse Transcriptase... (3R01GM105876-02S1)

    Retrovirus population diversity within infected hosts is commonly high due in part to elevated rates of replication, mutation, and recombination. This high genetic diversity often complicates the development of effective diagnostics, vaccines, and antiviral drugs. This ...

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271,969 research outcomes, page 1 of 27,197