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44,643 research outcomes, page 1 of 4,465
  • publication . Article . 2015
    Open Access English
    Authors:
    Jennifer McDuff; Alison Phinney;
    Persistent Identifiers
    Publisher: SAGE Publishing
    Project: CIHR

    Physical activity is beneficial for people with dementia, but little research explores subjective experiences of physical activity in this population. Interpretive description guided the analysis of 26 interviews conducted with 12 people with dementia. Three themes desc...

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  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    Alexander Dhaliwal; Maikel C. Rheinstädter; Adree Khondker; Sokunthearath Saem; Cécile Fradin; Ahmad Mahmood; Jose M. Moran-Mirabal;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: CIHR

    With the advent of polymyxin B (PmB) resistance in bacteria, the mechanisms for mcr-1 resistance are of crucial importance in the design of novel therapeutics. The mcr-1 phenotype is known to decrease membrane charge and increase membrane packing by modification of the ...

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  • publication . Article . Other literature type . 2013
    Open Access English
    Authors:
    Jean-Pierre Majoral; Rajiv Midha; Jacob Alant; Antos Shakhbazau; Anne-Marie Caminade; Dzmitry Shcharbin; Maria Bryszewska; Chandan B. Mohanty;
    Persistent Identifiers
    Publisher: ELSEVIER SCIENCE BV
    Project: CIHR , EC | NANOGENE (316730)

    International audience; Increased production of neurotrophic factors (NTFs) is one of the key responses seen following peripheral nerve injury, making them an attractive choice for pro-regenerative gene therapies. However, the downside of over-expression of certain NTFs...

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  • publication . Article . 2007
    Open Access English
    Authors:
    Jean-Claude Tabet; Annie Desmons; Michel Salzet; R Day; Isabelle Fournier; Rémi Lemaire;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: CIHR

    International audience; Formalin fixation, generally followed by paraffin embedding, is the standard and well-established processing method employed by pathologist. This treatment conserves and stabilizes biopsy samples for years. Analysis of FFPE tissues from biopsy li...

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  • publication . Article . 2009
    Open Access English
    Authors:
    Katie S. Lekx; Peter A. Merrifield; Huafu Kong; Pam Zabel; Sudip Datta; Gerald Wisenberg; Rupinder Mann; Glenn Wells; Jane Sykes; Frank S. Prato; ...
    Persistent Identifiers
    Publisher: Springer Nature
    Project: CIHR

    <p>Abstract</p> <p>Background</p> <p>The clinical application of stem cell therapy for myocardial infarction will require the development of methods to monitor treatment and pre-clinical assessment in a large animal model, to determine its effectiveness and the optimum ...

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  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Daniel J. Dutton; Jennifer D. Zwicker; Ramesh Lamsal;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: CIHR

    Background Early detection of neurodevelopmental disorders (NDDs) enables access to early interventions for children. We assess the Ages and Stages Questionnaire (ASQ)’s ability to identify children with a NDD in population data. Method Children 4 to 5 years old in the ...

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  • publication . Preprint . Article . 2020
    Open Access
    Authors:
    Vinci Au; Catharine H. Rankin; Donald G. Moerman; Troy A. McDiarmid;
    Publisher: Cold Spring Harbor Laboratory
    Project: CIHR

    <jats:title>Abstract</jats:title><jats:p>Improved genome engineering methods that enable automation of large and precise edits are essential for systematic investigations of genome function. We adapted <jats:italic>peel-1</jats:italic> negative selection to an optimized...

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  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Aline Bogossian; Jan Willem Gorter; Eric Racine;
    Persistent Identifiers
    Publisher: BMJ Publishing Group
    Project: CIHR

    <jats:sec><jats:title>Introduction</jats:title><jats:p>As adolescents with neurodisabilities near adulthood, they and their caregivers will face the challenge of transferring from paediatric to adult healthcare systems. Despite the growing number of programmes designed ...

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  • publication . Article . 2009
    Open Access English
    Authors:
    Andrew R. Willan; Andrew W. Howard; Linda Rothman; Colin Macarthur; Alison Macpherson;
    Persistent Identifiers
    Publisher: Public Library of Science
    Project: CIHR

    In a randomized trial of elementary schools in Toronto, Andrew Howard and colleagues show that granitic sand playground surfaces reduce the risk of arm fractures from playground falls when compared with wood fiber surfaces.

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  • publication . Article . 2014
    Open Access
    Authors:
    Cynthia Lokker; Deepa Mathew; K. Ann McKibbon; Heather Colquhoun;
    Persistent Identifiers
    Project: CIHR

    BackgroundIn 2008, WhatisKT wiki was launched as a collaborative platform for knowledge translation (KT) researchers and stakeholders to debate the use and definitions of KT-related terms. The wiki has definitions for over 110 terms from disciplines including health car...

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44,643 research outcomes, page 1 of 4,465