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9 research outcomes, page 1 of 1
  • publication . Article . Other literature type . 2015
    Open Access English
    Authors:
    Ashish Kumar; Ozren Polasek; Peter Joshi; Panos Deloukas; Ian Sayers; Åsa Johansson; Mika Kähönen; Martin Tobin; Stefan Enroth; Deborah Jarvis; ...
    Publisher: Nature Publishing Group
    Project: AKA | The Cardiovascular Risk i... (121584), RCUK | Centre for Cognitive Agei... (MR/K026992/1), SNSF | Swiss Study on Air Pollut... (3200-042532), NIH | Genetics of cardiovascula... (5R01HL087679-02), AKA | Impact of childhood growt... (134309), SNSF | Swiss Cohort Study on Air... (33CS30_134276), WT | Cambridge Institute for M... (079895), SNSF | Swiss Cohort Study on Air... (33CSC0-108796), SNSF | The SAPALDIA II Cohort St... (3100-059302), SNSF | The SAPALDIA II Cohort St... (3247-065896),...

    Lung function measures are used in the diagnosis of chronic obstructive pulmonary disease. In 38,199 European ancestry individuals, we studied genome-wide association of forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC with 1000 Genomes P...

  • publication . Article . 2020
    Open Access
    Authors:
    Klarić, Lucija; Tsepilov, Yakov A.; Stanton, Chloe M.; Mangino, Massimo; Sikka, Timo Tõnis; Esko, Tõnu; Pakhomov, Eugene; Salo, Perttu; Deelen, Joris; McGurnaghan, Stuart J.; ...
    Publisher: American Association for the Advancement of Science (AAAS)
    Project: EC | ePerMed (692145), NWO | NCHA Subsidiebesluit 2008... (2300155116), HRZZ | Pleitropy, gene networks ... (IP-2013-11-8875), RCUK | Quantitative Traits in He... (MC_UU_00007/10), NWO | BBMRI-NL2.0: The NL-Bioba... (2300184368), EC | IDEAL (259679), MZOS | Determinants of health an... (216-1080315-0302), EC | HIGHGLYCAN (278535), WT , EC | MIMOMICS (305280),...

    Variation in key transcription factors and glycogenes modifies IgG glycosylation and has an influence on inflammatory diseases.

  • publication . Article . Other literature type . Preprint . 2016
    Open Access
    Authors:
    Wedemeyer, S.; Bastian, T.; Brajša, R.; Hudson, H.; Fleishman, G.; Loukitcheva, M.; Fleck, B.; Kontar, E.P.; De Pontieu, B.; Yagoubov, P.; ...
    Publisher: Springer Science and Business Media LLC
    Project: HRZZ | Solar and Stellar Variabi... (IP-2013-11-6212), EC | SOLARNET (312495), EC | F-CHROMA (606862), EC | RADIOSUN (295272), NSF | Coronal Magnetography of ... (1250374), RCUK | Warwick Astrophysics Cons... (ST/L000733/1), EC | EHEROES (284461), NSF | Probing Solar Flares Usin... (1262772), EC | SERAF (304265), FWF | Magnetic Rossby waves on ... (P 26181)

    Comment: 73 pages, 21 figures ; Space Science Reviews (accepted December 10th, 2015); accepted version

  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    E. Sahin; Xavier Derkx;
    Publisher: American Physical Society (APS)
    Project: RCUK | University of the West of... (ST/P005101/1), HRZZ | Nuclear structure and rea... (IP-2013-11-7194), RCUK | University of the West of... (ST/L005808/1)
  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Shrine, Nick; Guyatt, Anna L; Erzurumluoglu, A Mesut; Jackson, Victoria E; Hobbs, Brian D; Melbourne, Carl A; Batini, Chiara; Fawcett, Katherine A; Song, Kijoung; Sakornsakolpat, Phuwanat; ...
    Project: SNSF | SAPALDIA COHORT STUDY: Im... (32473B-104284), NIH | CLINICAL CENTER FOR THE L... (N01HR076101-006), AKA | Well-being and health: Re... (104781), NIH | LUNG VOLUME REDUCTION STU... (N01HR076108-004), NIH | Identifying Genetic Deter... (5R01HL113264-04), EC | ALEC (633212), NIH | Genetic and Genomic Chara... (1R01HL135142-01A1), WT | The genetics of weight, B... (076113), HRZZ | Pleitropy, gene networks ... (IP-2013-11-8875), NIH | CLINICAL COORDINATING CEN... (N01HR076119-002),...

    Editorial summary: A genome-wide association study in over 400,000 individuals identifies 139 new signals for lung function. These variants can predict chronic obstructive pulmonary disease in independent, trans-ethnic cohorts.

  • publication . Article . 2019
    Open Access English
    Authors:
    Andrew London;
    Publisher: Nature Publishing Group
    Project: EC | EUROfusion (633053), RCUK | Sir Henry Royce Institute... (EP/P021727/1), HRZZ | MeV Ion Beam Induced Chan... (IP-2013-11-8127)

    <jats:title>Abstract</jats:title> <jats:p>The effects of radiation damage on materials are strongly dependant on temperature, making it arguably the most significant parameter of concern in nuclear engineering. Owing to the challenges and expense of irradiating and test...

  • publication . Preprint . Article . 2015
    Open Access English
    Authors:
    Yu, Jing Fei; Ramshaw, B. J.; Kokanović, Ivan; Modic, K. A.; Harrison, N.; Day, James; Liang, Ruixing; Hardy, W. N.; Bonn, D. A.; McCollam, A.; ...
    Project: RCUK | Fermi Surface Reconstruct... (EP/K016709/1), HRZZ | Transport, magnetic and t... (IP-2013-11-6216), NSERC , NSF | National High Magnetic Fi... (1157490)

    Comment: 15 pages, 7 figures

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Jelena Zeleznjak; Branka Popovic; Alec Redwood; Hartmut Hengel; Astrid Krmpotic; Stipan Jonjic; Vanda Juranic Lisnic;
    Publisher: Rockefeller University Press
    Project: HRZZ | Virus-specific Activating... (IP-2013-11-7132), RCUK | Regulatory role of non-co... (G1002523)

    Železnjak et al. demonstrate that two MCMV-encoded proteins interact with MHC I molecules, forming an altered-self complex that prevents missing self recognition by increasing specificity for inhibitory Ly49 receptors. This led to the evolution of CMV-specific activatin...

  • publication . Article . 2016
    Open Access English
    Authors:
    Tom MacGillivray; Simon R. Cox; Emanuele Trucco; Joanna Wardlaw; Ian J Deary;
    Publisher: BMJ Publishing Group
    Project: WT , RCUK | Centre for Cognitive Agei... (MR/K026992/1), HRZZ | Pleitropy, gene networks ... (IP-2013-11-8875), RCUK | Multi-modal retinal bioma... (EP/M005976/1)

    Aim<br/>To examine the relationship between retinal vascular morphology and cognitive abilities in a narrow-age cohort of community-dwelling older people. <br/>Methods<br/>Digital retinal images taken at age ~73 years from 683 participants of the Lothian Birth Cohort 19...

9 research outcomes, page 1 of 1
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