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2,528 research outcomes, page 1 of 253
  • publication . Article . 2015
    Open Access
    Authors:
    Jane Davies; Onn Min Kon; Amelia Shoemark; Sebastian Johnston;
    Publisher: Elsevier BV
    Project: RCUK | Mechanisms of Deficient I... (G0601236), RCUK | MRC-Asthma UK Centre in A... (G1000758), EC | MORIAE (233015), NHMRC | Molecular Regulation of B... (1016647), NHMRC | Molecular Regulation of B... (461219), EC | PREDICTA (260895), WT

    Background Rhinovirus infections are the dominant cause of asthma exacerbations, and deficient virus induction of IFN-α/β/λ in asthmatic patients is important in asthma exacerbation pathogenesis. Mechanisms causing this interferon deficiency in asthmatic patients are un...

  • publication . Article . Preprint . Other literature type . 2020
    Open Access
    Authors:
    David Moxey; Chris D. Cantwell; Yan Bao; Andrea Cassinelli; Giacomo Castiglioni; Sehun Chun; Emilia Juda; Ehsan Kazemi; Kilian Lackhove; Julian Marcon; ...
    Publisher: Elsevier
    Project: RCUK | Vortex Induced Vibration ... (EP/K037536/1), EC | RECORD (312444), RCUK | Arteries and Algorithms: ... (EP/C539834/1), EC | ExaFLOW (671571), NSF | GV: Small: Collaborative ... (0914564), EC | IDIHOM (265780), RCUK | libhpc: Intelligent Compo... (EP/I030239/1), RCUK | libhpc Stage II: A Long-t... (EP/K038788/1), RCUK | UK Turbulence Consortium (EP/H000208/1), NSF | The Best of Both: Toward ... (1521748),...

    Comment: 21 pages, 14 figures

  • publication . Article . Other literature type . Conference object . 2016
    Open Access
    Authors:
    Javier Aizpurua; Angela Demetriadou; Rohit Chikkaraddy;
    Publisher: American Chemical Society (ACS)
    Project: RCUK | Cambridge NanoScience thr... (EP/G037221/1), RCUK | Nano-Optics to controlled... (EP/L027151/1), EC | LINASS (320503)

    This is an open access article published under a Creative Commons Attribution (CC-BY) License.-- et al.

  • publication . Article . Preprint . 2015
    Open Access English
    Authors:
    Malijevský, A. (Alexandr); Parry, A.O.;
    Publisher: American Physical Society
    Project: RCUK | Creating macroscale effec... (EP/J009636/1)

    We study bridging transitions between spherically and cylindrically shaped particles (colloids) of radius R separated by a distance H that are dissolved in a bulk fluid (solvent). Using macroscopics, microscopic density-functional theory, and finite-size scaling theory,...

  • publication . Article . 2017
    Open Access
    Authors:
    James Kinross; Kirill Veselkov; Nicole Strittmatter;
    Project: RCUK | Development of a rapid ba... (BB/L020858/1), EC | METASPACE (634402)

    Abstract Hierarchical classification (HC) stratifies and classifies data from broad classes into more specific classes. Unlike commonly used data classification strategies, this enables the probabilistic prediction of unknown classes at different levels, minimizing the ...

  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Short, Rebecca; Gurung, Rajina; Rowcliffe, Marcus; Hill, Nicholas; Milner-Gulland, E. J.;
    Publisher: Public Library of Science (PLoS)
    Project: RCUK | Science and Solutions for... (NE/L002515/1)

    Free or subsidised mosquito net (MN) distribution has been an increasingly important tool in efforts to combat malaria in recent decades throughout the developing world, making great strides towards eradicating this hugely detrimental disease. However, there has been in...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Pazoki, Raha; Evangelou, Evangelos; Mosen-Ansorena, David; Pinto, Rui Climaco; Karaman, Ibrahim; Blakeley, Paul; Gill, Dipender; Zuber, Verena; Elliott, Paul; Tzoulaki, Ioanna; ...
    Publisher: Nature Publishing Group
    Project: RCUK | MRC-PHE Centre for Enviro... (MR/L01341X/1), RCUK | MICA: UK MEDical BIOinfor... (MR/L01632X/1), WT | Applying genome-wide asso... (206046)

    Levels of sodium and potassium in urine are associated with cardiovascular traits. Here, Pazoki et al. perform genome-wide association studies for urinary sodium and potassium secretion and identify 50 and 13 novel loci, respectively, some of which show a potential caus...

  • publication . Other literature type . Article . Conference object . 2018
    Open Access
    Authors:
    Rafael Ayala; Joram Posma; Nikita Harvey; Marc-Emmanuel Dumas; Dominique Gauguier;
    Publisher: Oxford University Press (OUP)
    Project: RCUK | Identification of Metabol... (MR/S004033/1), RCUK | DTA - Imperial College Lo... (EP/M506345/1)

    Abstract Motivation Data processing is a key bottleneck for 1H NMR-based metabolic profiling of complex biological mixtures, such as biofluids. These spectra typically contain several thousands of signals, corresponding to possibly few hundreds of metabolites. A number ...

  • publication . Article . 2015
    Open Access English
    Authors:
    Alexis Barr; Chris Bakal;
    Publisher: Nature Publishing Group
    Project: RCUK | Parameterisation of devel... (BB/J017183/1)

    <jats:title>Abstract</jats:title> <jats:p>How multiple spindle assembly pathways are integrated to drive bipolar spindle assembly is poorly understood. We performed an image-based double RNAi screen to identify genes encoding Microtubule-Associated Proteins (MAPs) that ...

  • publication . Article . Report . Other literature type . 2017
    Open Access
    Authors:
    Iain Johnston; Mauricio Barahona;
    Publisher: Frontiers Media
    Project: RCUK | EPSRC Centre for Mathemat... (EP/N014529/1)

    Precision medicine refers to the idea of delivering the right treatment to the right patient at the right time, usually with a focus on a data-centred approach to this task. In this perspective piece, we use the term ``precision healthcare'' to describe the development ...

2,528 research outcomes, page 1 of 253
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