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177 research outcomes, page 1 of 18
  • publication . Preprint . Conference object . 2016
    Open Access English
    Authors:
    Gaboardi, Marco; Lim, Hyun-Woo; Rogers, Ryan M.; Vadhan, Salil P.;
    Project: NSF | TWC: Frontier: Privacy To... (1237235), RCUK | PrivInfer - Programming L... (EP/M022358/1)

    Engineering and Applied Sciences

  • publication . Other literature type . Article . 2015
    Open Access
    Authors:
    Martin Hyde; Mika Kivimaki;
    Publisher: Oxford University Press (OUP)
    Project: NIH | SOCIAL AND OCCUPATIONAL I... (5R01HL036310-09), AKA | Determinants of healthy a... (264944), RCUK | Determinants of healthy a... (ES/K01336X/1)

    Background. The number of diseases and physical functioning difficulties tend to increase with age. The aim of this study was to examine the trajectories of physical functioning across age groups and whether the trajectories differ according to disease status in differe...

  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Beyer, Sebastian E; Sanghvi, Mihir M; Aung, Nay; Hosking, Alice; Cooper, Jackie A; Paiva, José Miguel; Lee, Aaron M; Fung, Kenneth; Lukaschuk, Elena; Carapella, Valentina; ...
    Publisher: Public Library of Science (PLoS)
    Project: RCUK | MICA: Medical Bioinformat... (MR/L016311/1), RCUK | Physical activity epidemi... (MC_UU_12015/3), WT , RCUK | SmartHeart: Next-generati... (EP/P001009/1)

    <h4>Background</h4> <p>Handgrip strength, a measure of muscular fitness, is associated with cardiovascular (CV) events and CV mortality but its association with cardiac structure and function is unknown. The goal of this study was to determine if handgrip strength is as...

  • publication . Other literature type . Article . 2015
    Open Access
    Authors:
    Yuming Guo; Eric Lavigne; Aurelio Tobías; Masahiro Hashizume; Antonio Gasparrini;
    Publisher: Columbia University
    Project: NHMRC | Uncoupled Research Fellow... (553043), RCUK | A general conceptual and ... (G1002296)

    BACKGROUND: Recent investigations have reported a decline in the heat-related mortality risk during the last decades. However, these studies are frequently based on modeling approaches that do not fully characterize the complex temperature-mortality relationship, and ar...

  • publication . Other literature type . Article . 2016
    Open Access
    Authors:
    Altenhoff, Adrian M; Boeckmann, Brigitte; Capella-Gutierrez, Salvador; Dalquen, Daniel A; DeLuca, Todd; Forslund, Kristoffer; Huerta-Cepas, Jaime; Linard, Benjamin; Pereira, Cécile; Pryszcz, Leszek P; ...
    Publisher: Springer Science and Business Media LLC
    Project: EC | NONCODEVOL (310325), NIH | UniProt: A centralized pr... (3U41HG007822-04S1), WT | Ensembl (095908), NSF | EAGER: Towards a self-org... (1355632), NIH | Gene Ontology Consortium (4U41HG002273-16), SNSF | Harnessing Phylogenetic V... (PP00P3_150654), RCUK | Automated identification ... (BB/L018241/1), NIH | The Monarch Initiative: L... (5R24OD011883-07)

    This work was supported by Swiss National Science Foundation grant PP00P3_150654 (to C.D.), UK Biotechnology and Biological Sciences Research Council grant BB/L018241/1 (to C.D.), Spanish Ministry of Economy and Competitiveness grant BIO2012-37161 (to T.G.), Qatar Natio...

  • publication . Article . Other literature type . 2012
    Open Access English
    Authors:
    Matthew Broome; Isabel Valli; Paul Allen; Federico Turkheimer; Paolo Fusar-Poli; Oliver Howes; Philip McGuire; Renaud Lambiotte;
    Publisher: Elsevier
    Project: RCUK | Networks: Emergence and d... (EP/E049451/1)

    Highlights ► Performed between-groups analysis of graph theoretical data derived from fMRI. ► Compared at-risk mental state patients with and without subsequent transition to psychosis. ► At-risk patients with subsequent disease manifestation show abnormal network topol...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Christian Weber; Johan Duchene; Antal Rot; Maria Casanova-Acebes; remco megens; Andrés Hidalgo; Jorge Caamano;
    Project: EC | PROVASC (692511), RCUK | Strategic Appointment of ... (G0802838), SNSF | Interplay of classical an... (CRSII3_160719), WT | The functional and clinic... (090962)

    Healthy individuals of African ancestry have neutropenia that has been linked with the variant rs2814778(G) of the gene encoding atypical chemokine receptor 1 (ACKR1). This polymorphism selectively abolishes the expression of ACKR1 in erythroid cells, causing a Duffy-ne...

  • publication . Other literature type . Article . 2014
    Open Access
    Authors:
    Nicholas H. Brown; Steven Marygold; Peter McQuilton;
    Publisher: Oxford University Press (OUP)
    Project: RCUK | Using GO to enhance the u... (G1000968), NIH | FLYBASE: A DROSOPHILA GEN... (5U41HG000739-25)

    Release 6, the latest reference genome assembly of the fruit fly Drosophila melanogaster, was released by the Berkeley Drosophila Genome Project in 2014; it replaces their previous Release 5 genome assembly, which had been the reference genome assembly for over 7 years....

  • publication . Article . 2017
    Open Access English
    Authors:
    Albert Barabasi; William Schafer; Yee Lian Chew; Petra E. Vértes; Gang Yan;
    Publisher: Nature Publishing Group
    Project: RCUK | Modelling the Development... (MR/K020706/1), NIH | Caenorhabditis Genetics C... (1P40OD010440-01), WT | Identifying novel sensory... (103784), EC | CIMPLEX (641191)

    Lesioning studies have provided important insight into the functions of brain regions in humans and other animals. In the nematode Caenorhabditis elegans, with a small nervous system of 302 identified neurons, it is possible to generate lesions with single cell resoluti...

  • publication . Article . Other literature type . 2013
    Open Access English
    Authors:
    Patrick Concannon; Soumya Raychaudhuri;
    Publisher: Public Library of Science
    Project: NIH | Bioinformatics and Popula... (1K08AR055688-01A1), WT | A national DNA control se... (068545), NIH | Fine-mapping the MHC asso... (1R01AR062886-01), NIH | Type 1 Diabetes Genetics ... (1U01DK062418-01), RCUK | Assessment of biomedical ... (G0000934)

    DNA sequence variation within human leukocyte antigen (HLA) genes mediate susceptibility to a wide range of human diseases. The complex genetic structure of the major histocompatibility complex (MHC) makes it difficult, however, to collect genotyping data in large cohor...

177 research outcomes, page 1 of 18
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