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340 research outcomes, page 1 of 34
  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Emily J Jones; Susie Chandler; Leslie Tucker; Sarah Lloyd-Fox; Andrew Pickles; Greg Pasco; giorgia bussu; Erica Salomone; Simon Baron-Cohen; Kelvin Davies; ...
    Project: RCUK | The Development of Social... (MR/K021389/1), EC | BRAINVIEW (642996), RCUK | The Typical and Atypical ... (G0701484)

    We integrated multiple behavioural and developmental measures from multiple time-points using machine learning to improve early prediction of individual Autism Spectrum Disorder (ASD) outcome. We examined Mullen Scales of Early Learning, Vineland Adaptive Behavior Scale...

  • publication . Article . 2015
    Open Access English
    Authors:
    Ronald, Angelica;
    Publisher: Elsevier
    Project: RCUK | Genetic and environmental... (G1100559)

    It is common, particularly in young people, to report psychotic experiences (PEs) such as feeling paranoid and having hallucinations. The questions of the role of genes and environment on PEs in the general population, and how PEs relate to schizophrenia, have not, unti...

  • publication . Conference object . Article . Other literature type . 2017
    Open Access
    Authors:
    Angelica Ronald; Robert Plomin; Tom McAdams; Rosa Cheesman; Philip S Dale; Saskia Selzam;
    Project: RCUK | Origins of learning diffi... (MR/M021475/1), NIH | Colorado Adoption/Twin St... (1R01AG046938-01A1), EC | ACTION (602768), RCUK | Origins of learning diffi... (G0901245), RCUK | Genetic and environmental... (G1100559)

    Abstract For most complex traits, DNA-based heritability (‘SNP heritability’) is roughly half that of twin-based heritability. A previous report from the Twins Early Development Study suggested that this heritability gap is much greater for childhood behaviour problems ...

  • publication . Article . Other literature type . 2015
    Open Access English
    Authors:
    Abigail Perrin; Gavin J. Wright; Moritz Treeck;
    Publisher: Elsevier (Cell Press)
    Project: EC | EVIMALAR (242095), WT | Wellcome Trust Sanger Ins... (098051), RCUK | Structural changes to hos... (G1100013)

    Egress from infected RBCs is a critical, but poorly understood, step in the malaria parasite’s lifecycle. Das et al. report that just prior to egress, proteolytic processing of parasite surface protein MSP1 activates a spectrin binding function, allowing the intracellul...

  • publication . Article . 2015
    Open Access English
    Authors:
    Arnab Pain; Jody Phelan; Taane Clark; Francesc Coll;
    Publisher: Medknow Publications
    Project: RCUK | The interactions between ... (MR/K000551/1)

    AbstractMycobacterium aurum (M. aurum) is an environmental mycobacteria that has previously been used in studies of anti-mycobacterial drugs due to its fast growth rate and low pathogenicity. The M. aurum genome has been sequenced and assembled into 46 contigs, with a t...

  • publication . Article . 2014
    Open Access English
    Authors:
    Shabih Shakeel; Sarah Jane Butcher; Arun Prasad Pandurangan; Maya Topf;
    Publisher: Academic Press
    Project: RCUK | Tools for Generating and ... (BB/K01692X/1), RCUK | Structural characterizati... (G0600084)

    AbstractFitting of atomic components into electron cryo-microscopy (cryoEM) density maps is routinely used to understand the structure and function of macromolecular machines. Many fitting methods have been developed, but a standard protocol for successful fitting and a...

  • publication . Article . 2012
    Open Access English
    Authors:
    Gliga, Teodora; Elsabbagh, Mayada; Hudry, K.; Charman, T.; Johnson, Mark H.;
    Publisher: Wiley
    Project: RCUK | The Typical and Atypical ... (G0701484)

    We investigated gaze following abilities as a prerequisite for word learning, in a population expected to manifest a wide range of individual variability – children with a family history of autism. Three-year-olds with or without a family history of autism took part in ...

  • publication . Article . Other literature type . 2009
    Open Access English
    Authors:
    Atsushi Senju; Uta Frith; Sarah J White; Victoria Southgate;
    Project: RCUK | The Typical and Atypical ... (G0701484)

    Udgivelsesdato: 2009-Aug-14 Adults with Asperger syndrome can understand mental states such as desires and beliefs (mentalizing) when explicitly prompted to do so, despite having impairments in social communication. We directly tested the hypothesis that such individual...

  • publication . Article . 2013
    Open Access English
    Authors:
    Juha Huiskonen; Maya Topf; Arun Prasad Pandurangan; Kay Grünewald; Tzviya Zeev-Ben-Mordehai;
    Project: NIH | STD TRAINING PROGRAM (5T32AI007234-03), AKA | Structures and Host Cell ... (218080), WT | Purchase of electron micr... (093305), AKA | Study on Virus-Host Cell ... (114649), NIH | Early Events in Herpes Si... (2R01AI076231-11A1), WT | Understanding the genetic... (090532), NIH | HSV-Receptor Interaction ... (5R01AI056045-03), RCUK | Structural characterizati... (G0600084)

    Highlights • Full-length gB ectodomain has a structure similar to the ectodomain lacking the MPR • The gB-bilayer structure reveals that the interaction is limited to the outer leaflet • gB trimers have an intrinsic propensity to interact laterally and form protein arra...

  • publication . Article . 2013
    Open Access English
    Authors:
    Huyet, Jessica; Naylor, Claire,; Savva, Christos,; Gibert, Maryse; Popoff, Michel; Basak, Ajit,; Motta, Andrea;
    Project: WT | Insights into pore-format... (089618), RCUK | The Gas-Gangrene Causing ... (G0700051)

    International audience; Clostridium perfringens Delta toxin is one of the three hemolysin-like proteins produced by C. perfringens type C and possibly type B strains. One of the others, NetB, has been shown to be the major cause of Avian Nectrotic Enteritis, which follo...

340 research outcomes, page 1 of 34
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