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65 research outcomes, page 1 of 7
  • publication . Article . 2017
    Open Access
    Authors:
    Elizabeth Shephard; Bosiljka Milosavljevic; Mark Johnson; Francesca Happe; Tony Charman;
    Publisher: Springer Nature
    Project: RCUK | The Typical and Atypical ... (G0701484)

    Anxiety and threat bias were examined in 6-8-year-old children at familial-risk for Autism Spectrum Disorder (ASD) and low-risk (LR, n = 37) controls. The high-risk (HR) group was divided into those who met diagnostic criteria for ASD (HR-ASD, n = 15) and those who did ...

  • publication . Article . Conference object . Other literature type . 2018
    Open Access English
    Authors:
    Nyström, Pär; Gliga, Teodora; Nilsson Jobs, Elisabeth; Gredebäck, Gustaf; Charman, Tony; Johnson, Mark; Bölte, Sven; Falck-Ytter, Terje;
    Publisher: Nature Publishing Group
    Project: RCUK | The Typical and Atypical ... (G0701484)

    Autism spectrum disorder (ASD) is a neurodevelopmental condition affecting around 1% of the population. We previously discovered that infant siblings of children with ASD had stronger pupillary light reflexes compared to low-risk infants, a result which contrasts sharpl...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Sungho Tak; Victoria Southgate; Chiara Bulgarelli; Carina de Klerk;
    Publisher: Academic Press
    Project: EC | INTERACT (313398), RCUK | The Typical and Atypical ... (G0701484)

    Tracking the connectivity of the developing brain from infancy through childhood is an area of increasing research interest, and fNIRS provides an ideal method for studying the infant brain as it is compact, safe and robust to motion. However, data analysis methods for ...

  • publication . Other literature type . Article . 2014
    Open Access
    Authors:
    Teodora Gliga; Rachael Bedford; Mark Johnson; Emily J Jones; Tony Charman;
    Publisher: Elsevier BV
    Project: RCUK | The Typical and Atypical ... (G0701484)

    Highlights • Studies of infants at-risk could reveal the developmental origin of autism. • Behavioral and brain markers differentiate infants that develop autism symptoms from controls, during the first year of life. • Little evidence for decreased social orienting or s...

  • publication . Article . 2013
    Open Access English
    Authors:
    Rigato, Silvia; Menon, E.; Farroni, Teresa; Johnson, Mark H.;
    Publisher: Wiley
    Project: RCUK | The Typical and Atypical ... (G0701484), EC | HEMSDEV (241242), WT | Developmental origins of ... (073985)

    In this study, 4-month-old infants’ and adults’ spontaneous preferences for emotional and neutral displays with direct and averted gaze are investigated using visual preference paradigms. Specifically, by presenting two approach-oriented emotions (happiness and anger) a...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Jonathan Green; Leslie Tucker; Anna Kolesnik; Andrew Pickles; Emily J Jones; Erica Salomone; Gareth Evans; Simon Baron-Cohen; Kelvin Davies; Tony Charman;
    Project: EC | EU-AIMS (115300), RCUK | The Development of Social... (MR/K021389/1), RCUK | The Typical and Atypical ... (G0701484)

    Background Prospective studies of infants at familial risk for autism spectrum disorder (ASD) have yielded insights into the earliest signs of the disorder but represent heterogeneous samples of unclear aetiology. Complementing this approach by studying cohorts of infan...

  • publication . Article . 2017
    Open Access English
    Authors:
    Bedford, Rachael; Gliga, Teodora; Shephard, Elizabeth; Elsabbagh, Mayada; Charman, T.; Johnson, Mark H.;
    Publisher: BioMed Central
    Project: RCUK | The Typical and Atypical ... (G0701484)

    Background\ud \ud Prospective studies of infants at high familial risk for autism spectrum disorder (ASD) have identified a number of putative early markers that are associated with ASD outcome at 3 years of age. However, some diagnostic changes occur between toddlerhoo...

  • publication . Article . 2016
    Open Access English
    Authors:
    Rachael Bedford; Andrew Pickles; Emily J Jones; Tony Charman;
    Publisher: BioMed Central
    Project: EC | TRIGGER (611034), EC | EU-AIMS (115300), RCUK | The Typical and Atypical ... (G0701484), WT

    Background Although it is well established that the prevalence of autism spectrum disorder (ASD) is higher in males than females, there is relatively little understanding of the underlying mechanisms and their developmental time course. Sex-specific protective or risk f...

  • publication . Article . 2011
    Open Access English
    Authors:
    Senju, Atsushi; Southgate, Victoria; Snape, C.; Leonard, M.; Csibra, Gergely;
    Publisher: Sage
    Project: RCUK | The Typical and Atypical ... (G0701484)

    In the research reported here, we investigated whether 18-month-olds would use their own past experience of visual access to attribute perception and consequent beliefs to other people. Infants in this study wore either opaque blindfolds (opaque condition) or trick blin...

  • publication . Article . 2017
    Open Access English
    Authors:
    Clare Elwell; Sarah Lloyd-Fox; Ilias Tachtsidis;
    Publisher: Nature Publishing Group
    Project: RCUK | BB/J014567/1 (BB/J014567/1), WT | Early bedside biomarkers ... (104580), RCUK | The Development of Social... (MR/K021389/1), RCUK | The Typical and Atypical ... (G0701484)

    While near-infrared spectroscopy (NIRS) haemodynamic measures have proven to be vastly useful in investigating human brain development, the haemodynamic response function (HRF) in infants is not yet fully understood. NIRS measurements of the oxidation state of mitochond...

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