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231 research outcomes, page 1 of 24
  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Oliver Stegle; Maria Florescu; Kieran R Campbell; Davis J. McCarthy; David Laehnemann; Giacomo Corleone; Catalina Vallejos; Mark Robinson; Felix Mölder; Alexander Zelikovsky;
    Project: NIH | Statistical Methods for t... (4R00HG009007-03), NIH | QuBBD: Viral Evolution an... (1R01EB025022-01), NSF | CAREER: Algorithms for Ne... (1053753), NIH | Discovering disease-causa... (5R00HG008399-04), NWO | Statistical Models for St... (2300178920), SNSF | Defining the identity and... (CRSII5_177208), SNSF | The structure and functio... (310030B_182828), NIH | Computational Characteriz... (7R01HG007069-04), EC | EpiPredict (642691), WT ,...

    textabstractThe recent boom in microfluidics and combinatorial indexing strategies, combined with low sequencing costs, has empowered single-cell sequencing technology. Thousands-or even millions-of cells analyzed in a single experiment amount to a data revolution in si...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Jamie Inshaw; Chris Wallace; Neil Walker; Leonardo Bottolo;
    Project: WT , WT | The genetics of weight, B... (076113), RCUK | The Alan Turing Institute (EP/N510129/1), WT | Diabetes and Inflammation... (107212), NIH | Type 1 Diabetes Genetics ... (1U01DK062418-01), WT | Diabetes and Inflammation... (091157), NIH | Molecular modeling of sol... (1ZIADK013039-04), WT | Partitioning autoimmune d... (107881)

    Aims/hypothesis The genetic risk of type 1 diabetes has been extensively studied. However, the genetic determinants of age at diagnosis (AAD) of type 1 diabetes remain relatively unexplained. Identification of AAD genes and pathways could provide insight into the earlie...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Chico Q. Camargo; Jonathan Bright; Scott A. Hale;
    Publisher: The Royal Society
    Project: RCUK | The Alan Turing Institute (EP/N510129/1), RCUK | Innovate UK: NEXUS - Real... (NE/N00728X/1)

    <jats:p>Accurate modelling of local population movement patterns is a core, contemporary concern for urban policymakers, affecting both the short-term deployment of public transport resources and the longer-term planning of transport infrastructure. Yet, while macro-lev...

  • publication . Preprint . 2017
    Open Access English
    Authors:
    Bradshaw, John; Matthews, Alexander G. de G.; Ghahramani, Zoubin;
    Project: RCUK | The Alan Turing Institute (EP/N510129/1), RCUK | Deep Probabilistic Models... (EP/N014162/1)

    Deep neural networks (DNNs) have excellent representative power and are state of the art classifiers on many tasks. However, they often do not capture their own uncertainties well making them less robust in the real world as they overconfidently extrapolate and do not n...

  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    Kieran R Campbell; Christopher Yau;
    Publisher: Springer Science and Business Media LLC
    Project: RCUK | From single cells to popu... (MR/P02646X/1), RCUK | The Alan Turing Institute (EP/N510129/1)

    Bayesian statistical learning provides a coherent probabilistic framework for modelling uncertainty in systems. This review describes the theoretical foundations underlying Bayesian statistics and outlines the computational frameworks for implementing Bayesian inference...

  • publication . Preprint . Article . 2018
    Open Access English
    Authors:
    Patrick Hohenecker; Thomas Lukasiewicz;
    Project: RCUK | RealPDBs: Realistic Data ... (EP/R013667/1), RCUK | The Alan Turing Institute (EP/N510129/1), RCUK | PrOQAW: Probabilistic Ont... (EP/J008346/1), RCUK | DBOnto: Bridging Database... (EP/L012138/1), RCUK | VADA: Value Added Data Sy... (EP/M025268/1)

    <jats:p>&#x0D; &#x0D; &#x0D; The ability to conduct logical reasoning is a fundamental aspect of intelligent human behavior, and thus an important problem along the way to human-level artificial intelligence. Traditionally, logic-based symbolic methods from the field of...

  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Andrew Burnie;
    Project: EC | FIN-TECH (825215), RCUK | The Alan Turing Institute (EP/N510129/1)

    The recent extreme volatility in cryptocurrency prices occurred in the setting of popular social media forums devoted to the discussion of cryptocurrencies. We develop a framework that discovers potential causes of phasic shifts in the price movement captured by social ...

  • publication . Article . Preprint . 2018
    Open Access
    Authors:
    Alfredo Nazábal; Pablo M. Olmos; Zoubin Ghahramani; Isabel Valera;
    Publisher: Elsevier
    Project: RCUK | Deep Probabilistic Models... (EP/N014162/1), RCUK | The Alan Turing Institute (EP/N510129/1)

    Abstract Variational autoencoders (VAEs), as well as other generative models, have been shown to be efficient and accurate for capturing the latent structure of vast amounts of complex high-dimensional data. However, existing VAEs can still not directly handle data that...

  • publication . Preprint . Conference object . 2020
    Open Access English
    Authors:
    Saengkyongam, S.; Silva, R.;
    Project: RCUK | The Alan Turing Institute (EP/N510129/1)

    Comment: Accepted to The Conference on Uncertainty in Artificial Intelligence (UAI) 2020

  • publication . Other literature type . Preprint . Article . Conference object . 2018
    Open Access
    Authors:
    Speicher, Till; Heidari, Hoda; Grgic-Hlaca, Nina; Gummadi, Krishna P; Singla, Adish; Weller, Adrian; Zafar, Muhammad Bilal;
    Publisher: Association for Computing Machinery (ACM)
    Project: RCUK | The Alan Turing Institute (EP/N510129/1), EC | FairSocialComputing (789373)

    Discrimination via algorithmic decision making has received considerable attention. Prior work largely focuses on defining conditions for fairness, but does not define satisfactory measures of algorithmic unfairness. In this paper, we focus on the following question: Gi...

231 research outcomes, page 1 of 24
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