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82 research outcomes, page 1 of 9
  • publication . Conference object . Article . 2016
    Open Access
    Authors:
    Meena Kumari; Rebecca E Lacey; Anne McMunn;
    Project: RCUK | Wellbeing and participati... (MC_UU_12019/5), RCUK | International Centre for ... (ES/J019119/1), RCUK | Enhancing the MRC Nationa... (MC_UU_12019/1), RCUK | Life course determinants ... (MC_UU_12019/4)

    The aim was to investigate whether the combined work-family life courses of British men and women were associated with differences in metabolic markers—waist circumference, blood pressure, high density lipoprotein cholesterol, triglycerides, and glycated haemoglobin—in ...

  • publication . Article . Conference object . 2016
    Open Access
    Authors:
    Rachel Cooper; Rebecca Hardy; Graciela Muniz Terrera;
    Publisher: Oxford University Press (OUP)
    Project: RCUK | Enhancing the MRC Nationa... (MC_UU_12019/1), RCUK | Mental Ageing (MC_UU_12019/3), RCUK | Life course determinants ... (MC_UU_12019/4)

    Background: Cognitive capabilities in childhood and in late life are inversely associated with mortality rates. However, it is unclear if adult cognition, at a time still relatively free from comorbidity, is associated with subsequent mortality, and whether this explain...

  • publication . Article . Other literature type . Conference object . 2014
    Open Access English
    Authors:
    Holmes, Michael V; Dale, Caroline E; Zuccolo, Luisa; Silverwood, Richard J; Guo, Yiran; Ye, Zheng; Prieto-Merino, David; Dehghan, Abbas; Trompet, Stella; Wong, Andrew; ...
    Project: NIH | CORONARY HEART DISEASE &S... (N01HC085080-018), NIH | CORONARY HEART DISEASE &S... (N01HC085081-016), NIH | Genome-Wide Association f... (5R01HL087641-02), WT | The Avon Longitudinal Stu... (092731), NHMRC | Maintaining and developin... (403963), RCUK | Vitamin D and health: gen... (G0601653), NIH | STUDY CORONARY HEART DISE... (N01HC048049-020), NIH | CORONARY HEART DISEASE AN... (N01HC085082-024), NHMRC | Predicting health and dis... (634492), NIH | CORONARY HEART DISEASE RI... (N01HC048050-038),...

    Lista completa dos Autores: Holmes MV, Dale CE, Zuccolo L, Silverwood RJ, Guo Y, Ye Z, Prieto-Merino D, Dehghan A, Trompet S, Wong A, Cavadino A, Drogan D, Padmanabhan S, Li S, Yesupriya A, Leusink M, Sundstrom J, Hubacek JA, Pikhart H, Swerdlow DI, Panayiotou AG, Borin...

  • publication . Article . 2015
    Open Access English
    Authors:
    Jones, R; Hardy, R; Sattar, N; Deanfield, JE; Hughes, A; Kuh, D; Murray, ET; Whincup, PH; Thomas, C; NSHD Scientific and Data Collection Teams;
    Project: RCUK | Enhancing the MRC Nationa... (MC_UU_12019/1), RCUK | Functional trajectories a... (MC_UU_12019/2), WT

    Social disadvantage across the life course is associated with a greater risk of coronary heart disease (CHD) and with established CHD risk factors, but less is known about whether novel CHD risk factors show the same patterns. The Medical Research Council National Surve...

  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    Ahmed Elhakeem; Jon Tobias;
    Publisher: Springer Science and Business Media LLC
    Project: RCUK | Life course determinants ... (MC_UU_12019/4), RCUK | Describing habitual level... (MR/K024973/1), RCUK | Enhancing the MRC Nationa... (MC_UU_12019/1)

    Background Little is known about how different physical activity (PA) parameters relate to cognitive function in older adults. Using accelerometers calibrated to detect vertical impacts from ground reaction forces we examined the associations of low, medium and higher i...

  • publication . Article . 2017
    Open Access English
    Authors:
    Cyrus Cooper; April Hartley; Jon Tobias; Ahmed Elhakeem; Charlotte Moss; Elaine Dennison; Rachel Cooper;
    Project: RCUK | Life course determinants ... (MC_UU_12019/4), RCUK | Enhancing the MRC Nationa... (MC_UU_12019/1)

    © 2018 Oxford University Press. All rights reserved. Background: High impact physical activity (PA) is thought to improve skeletal health, but its relation to other health outcomes are unclear. We investigated associations between PA impact magnitude and body mass index...

  • publication . Article . 2015
    Open Access English
    Authors:
    Alun Hughes; Rebecca Hardy; John Deanfield; Claudia Slimings; Peter Whincup; Naveed Sattar; Diana Kuh;
    Publisher: Elsevier Ireland Ltd
    Project: RCUK | Functional trajectories a... (MC_UU_12019/2), RCUK | Enhancing the MRC Nationa... (MC_UU_12019/1), WT

    Highlights • We examine associations of life course socioeconomic position (SEP) with novel coronary heart disease risk markers using novel methods to compare different life course models. • SEP during childhood was important for IL-6 and leptin, while SEP during both c...

  • publication . Article . Other literature type . Conference object . 2018
    Open Access
    Authors:
    Heidi Murray-Smith; Ashvini Keshavan; Sarah-Naomi James; Jonathan Schott;
    Publisher: Springer Science and Business Media LLC
    Project: RCUK | Computational models of n... (EP/J020990/1), WT , RCUK | UK Dementias Platform (MR/L023784/1), EC | EuroPOND (666992), RCUK | Mental Ageing (MC_UU_12019/3), RCUK | Enhancing the MRC Nationa... (MC_UU_12019/1)

    Objective Identifying and recruiting people with early pre-symptomatic Alzheimer’s disease to neuroimaging research studies is increasingly important. The extent to which results of these studies can be generalised depends on the recruitment and representativeness of th...

  • publication . Conference object . Article . 2017
    Open Access
    Authors:
    Alex Tsui; Diana Kuh; Marcus Richards; Daniel Davis;
    Project: WT | The population impact of ... (107467), RCUK | Enhancing the MRC Nationa... (MC_UU_12019/1), RCUK | Mental Ageing (MC_UU_12019/3)

    Abstract Introduction Few population studies have investigated whether longitudinal decline after delirium in mid-to-late life might affect specific cognitive domains. Methods Participants from a birth cohort completing assessments of search speed, verbal memory, and th...

  • publication . Conference object . Article . 2017
    Open Access
    Authors:
    Rebecca Hardy; Jane Maddock;
    Project: RCUK | Enhancing the MRC Nationa... (MC_UU_12019/1), RCUK | Epigenetic responses to s... (ES/N000404/1)

    Background Body size, nutrition and socioeconomic position (SEP) in early life have been associated with a range of later life health outcomes. Epigenetic regulation is one mechanism through which these early life factors may impact later life health. The aim of this re...

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