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64 research outcomes, page 1 of 7
  • publication . Article . 2017
    Open Access
    Authors:
    Claire Haworth; R. Adele H. Wang; Oliver S P Davis;
    Publisher: Springer Nature
    Project: NIH | Genetics, School environm... (1R01HD044454-01A2), RCUK | From Mendelian Randomizat... (MC_UU_12013/1), NIH | Colorado Adoption/Twin St... (1R01AG046938-01A1), EC | ACTION (602768), RCUK | Origins of learning diffi... (MR/M021475/1), RCUK | Determinants, Consequence... (MC_UU_12013/6), RCUK | Origins of learning diffi... (G0901245)

    Some life events appear heritable due to the genetic influence on related behaviours. Shared genetic influence between negative behaviours and negative life events has previously been established. This study investigated whether subjective wellbeing and positive life ev...

  • publication . Article . 2016
    Open Access English
    Authors:
    Marcus Munafo; Stephen Burgess; George Davey Smith;
    Publisher: Nature Publishing Group
    Project: WT | Causal inference in large... (100114), RCUK | From Mendelian Randomizat... (MC_UU_12013/1), RCUK | Determinants, Consequence... (MC_UU_12013/6)

    <p>Vitamin D deficiency is associated with increased risk of schizophrenia. However, it is not known whether this association is causal or what the direction of causality is. We performed two sample bidirectional Mendelian randomization analysis using single nucleotide ...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Claire Haworth; R. Adele H. Wang; S. Katherine Nelson-Coffey; Oliver S P Davis;
    Project: NIH | Colorado Adoption/Twin St... (1R01AG046938-01A1), EC | ACTION (602768), NIH | Genetics, School environm... (1R01HD044454-01A2), RCUK | Origins of learning diffi... (MR/M021475/1), RCUK | Origins of learning diffi... (G0901245), RCUK | From Mendelian Randomizat... (MC_UU_12013/1), RCUK | Determinants, Consequence... (MC_UU_12013/6)

    Interventions rarely have a universal effect on all individuals. Reasons ranging from participant characteristics, context and fidelity of intervention completion could cause some people to respond more positively than others. Understanding these individual differences ...

  • publication . Preprint . 2018
    Open Access English
    Authors:
    Amy E. Taylor; Rebecca C. Richmond; Teemu Palviainen; Anu Loukola; Jaakko Kaprio; Caroline Relton; George Davey Smith; Marcus R. Munafò;
    Publisher: Cold Spring Harbor Laboratory
    Project: RCUK | From Mendelian Randomizat... (MC_UU_12013/1), WT | The Avon Longitudinal Stu... (102215), RCUK | Accessible resource for i... (BB/I025263/1), RCUK | Accessible resource for i... (BB/I025751/1), RCUK | Determinants, Consequence... (MC_UU_12013/6), RCUK | Epigenetic Epidemiology (MC_UU_12013/2)

    <jats:title>Abstract</jats:title><jats:sec id="s1"><jats:title>Background</jats:title><jats:p>Given clear evidence that smoking lowers weight, it is possible that individuals with higher body mass index (BMI) smoke in order to lose or maintain their weight.</jats:p></ja...

  • publication . Article . 2014
    Open Access English
    Authors:
    Marcus Munafo; Matthew Hickman; Nicholas Timpson; George Davey Smith;
    Publisher: BioMed Central
    Project: WT | Characterising patterns a... (086684), RCUK | Causal Pathways to Substa... (G0800612), RCUK | Determinants, Consequence... (MC_UU_12013/6)

    Background Genome-wide association studies have revealed an association between several loci in the nicotinic acetylcholine receptor gene cluster CHRNA5-A3-B4 and daily cigarette consumption. Recent studies have sought to refine this phenotype, and have shown that a loc...

  • publication . Article . 2017
    Open Access English
    Authors:
    Marcus Munafo; Sally Adams;
    Publisher: John Wiley and Sons Inc.
    Project: RCUK | Determinants, Consequence... (MC_UU_12013/6)

    Objective<br/><br/>The aim of this study was to investigate the following: (a) the effects of acute alcohol on delay discounting; (b) the effects of drinking status on delayed discounting; and (c) whether these effects differ according to reward type (alcohol vs. money)...

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Claire Haworth; R. Adele H. Wang; Oliver S P Davis;
    Project: RCUK | From Mendelian Randomizat... (MC_UU_12013/1), WT , RCUK | Origins of learning diffi... (MR/M021475/1), RCUK | Determinants, Consequence... (MC_UU_12013/6), RCUK | Origins of learning diffi... (G0901245)

    <jats:p>Behavioral traits generally show moderate to strong genetic influence, with heritability estimates of around 50%. Some recent research has suggested that trust may be an exception because it is more strongly influenced by social interactions. In a sample of over...

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Massimo Mangino; Lavinia Paternoster; Gonneke Willemsen; Jaakko Kaprio; Anu-Maria Loukola; Leo-Pekka Lyytikäinen; Juho Olavi Wedenoja; C.C. Minica; Rachel Tyndale; René Pool; ...
    Project: EC | GMI (230374), NIH | Research Education in Sta... (1R25DA026119-01), AKA | The Application of 'Omics... (139635), EC | BBMRI-LPC (313010), WT , EC | ePerMed (692145), EC | ADDICTION (284167), NIH | Research Training: Psychi... (5T32MH020030-13), AKA | Genomic epidemiology of a... (265240), AKA | Genomic epidemiology of a... (263278),...

    Genome-wide association studies (GWAS) of complex behavioural phenotypes such as cigarette smoking typically employ self-report phenotypes. However, precise biomarker phenotypes may afford greater statistical power and identify novel variants. Here we report the results...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Angeliki Papadaki; Majid HA; Tin Tin Su;
    Project: RCUK | Diet, physical activity a... (MR/P013821/1), RCUK | Mediation analysis in lif... (MR/M020894/1), RCUK | Determinants, Consequence... (MC_UU_12013/6)

    17 years from the Malaysian Health and Adolescent Longitudinal Research Team study. PA pattern scores in boys were associated with higher fitness (r = 0.3) and lower fatness (r = &minus

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Marcus Munafo; Katie Drax; Olivia Maynard; Anna Blackwell;
    Project: RCUK | Smoking kills, but you ca... (ES/R003424/1), RCUK | Determinants, Consequence... (MC_UU_12013/6)

    Highlights • Drinkers underestimated the number of drinks that constituted 14 units. • Unit understanding was greater for novel unit labels compared to industry labels. • Motivation to drink less was higher for cancer and negatively-framed messages.

64 research outcomes, page 1 of 7
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