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130 research outcomes, page 1 of 13
  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Udo Wegmann; Andrea Telatin; Simon Funnell; Ariadna Miquel-Clopés;
    Publisher: John Wiley and Sons Inc.
    Project: RCUK | Application of a commensa... (BB/L004291/1), RCUK | Using engineered gut bact... (971525)

    Summary Plague caused by the Gram‐negative bacterium, Yersinia pestis, is still endemic in parts of the world today. Protection against pneumonic plague is essential to prevent the development and spread of epidemics. Despite this, there are currently no licensed plague...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Emiliano Bilotti; Ton Peijs; Han ZHANG; Yan Li;
    Publisher: Hindawi Limited
    Project: RCUK | Graphene-Reinforced Epoxi... (101257)

    <jats:p>A simple approach to deliver graphene or graphite nanoplatelets (GNPs) into carbon fibre reinforced plastic (CFRPs) to enhance the multifunctional properties of carbon/epoxy laminates was demonstrated. GNPs improved the typically low interlaminar mechanical, the...

  • publication . Master thesis . 2019
    Open Access Portuguese
    Authors:
    Freire, Daniel da Silva;
    Project: RCUK | Robust Machine Executable... (102308)

    Autonomous Surface Vehicles (ASVs), operating near ship harbors or relatively close to shorelines must be able to steer away from incoming vessels and other possible obstacles, be they dynamic or not. To do this, one must implement some type of multi-target tracking and...

  • publication . Article . 2017
    Open Access
    Authors:
    Luo, Quanshun; Kitchen, Matthew; Abubakri, Shahriar;
    Publisher: MDPI AG
    Project: RCUK | Development of a High Per... (720113)

    Ultrahigh strength steel 56NiCrMoV7 was austempered at 270 °C for different durations in order to investigate the microstructure evolution, carbon partitioning behaviour and hardness property. Detailed microstructure has been characterised using optical microscopy and f...

  • publication . Article . Other literature type . Conference object . 2019
    Open Access English
    Authors:
    Patel, Vruti; Bidault, Guillaume; Chambers, Joseph; Carobbio, Stefania; Everden, Angharad JT; Garcés, Concepción; Dalton, Lucy E; Gribble, Fiona; Vidal-Puig, Antonio; Marciniak, Stefan;
    Publisher: Nature Publishing Group
    Project: NHMRC | How do p75 and sortilin f... (1002610), RCUK | THE ROLE OF ENDOPLASMIC R... (G1002610), RCUK | Thin, Low Power and Light... (100140), WT | Cellular Medicine at the ... (100140), WT , WT | High Resolution Imaging i... (093026)

    Abstract Phosphorylation of the translation initiation factor eIF2α within the mediobasal hypothalamus is known to suppress food intake, but the role of the eIF2α phosphatases in regulating body weight is poorly understood. Mice deficient in active PPP1R15A, a stress-in...

  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Yong-Ju Huang; Georgia K. Mitrousia; Siti Nordahliawate M. Sidique; Aiming Qi; Bruce D. L. Fitt;
    Publisher: Public Library of Science (PLoS)
    Project: RCUK | Integrated control of Lep... (102641), RCUK | Strategies to increase du... (102100)

    Using cultivar resistance against pathogens is one of the most economical and environmentally friendly methods for control of crop diseases. However, cultivar resistance can be easily rendered ineffective due to changes in pathogen populations or environments. To test t...

  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Girijesh Prasad; Magda Bucholc; David Glass; KongFatt Wong-Lin; Anthony John; Haiying Wang;
    Publisher: Springer Science and Business Media LLC
    Project: RCUK | Extraction and modelling ... (102161)

    Abstract There is currently a lack of an efficient, objective and systemic approach towards the classification of Alzheimer’s disease (AD), due to its complex etiology and pathogenesis. As AD is inherently dynamic, it is also not clear how the relationships among AD ind...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Kim, Young Chan; López-Camacho, César; Garcia-Larragoiti, Nallely; Cano-Mendez, Alan; Hernandez-Flores, Karina Guadalupe; Domínguez-Alemán, Carlos Alonso; Antonieta Mar, Maria; Vivanco-Cid, Héctor; Viveros-Sandoval, Martha Eva; Reyes-Sandoval, Arturo;
    Project: RCUK | Protective efficacy and n... (972216), RCUK | Phase Ib trial of a simpl... (971557)

    Chikungunya fever is a debilitating disease caused by Chikungunya virus (CHIKV) that can result in long-lasting arthralgias. The early diagnosis of CHIKV relies on PCR during the acute infection phase to allow differential diagnosis with other co-circulating arboviruses...

  • publication . Other literature type . Article . 2019
    Open Access English
    Authors:
    CESAR LOPEZ-CAMACHO; Rafael Kroon Campos; Lorena Preciado-Llanes; Arturo Reyes-Sandoval; Sasha R. Azar;
    Publisher: Multidisciplinary Digital Publishing Institute
    Project: RCUK | Phase Ib trial of a simpl... (971557)

    Cap dose provided complete protection against a lethal virus challenge and prevented CHIKV-associated severe inflammation. These candidate vaccines supported survival equal to the attenuated 181/25 CHIKV reference vaccine but without the vaccine-related side effects, su...

  • publication . Article . Conference object . Other literature type . 2016
    Open Access
    Authors:
    Elnaz Yaghini; Helen D. Turner; Alix M. Le Marois; Klaus Suhling; Imad Naasani; Alexander J. MacRobert;
    Publisher: Elsevier BV
    Project: RCUK | Cadmium-free quantum dots... (101875)

    <p>Quantum dots (QDs) are attractive photoluminescence probes for biomedical imaging due to their unique photophysical properties. However, the potential toxicity of QDs has remained a major obstacle to their clinical use because they commonly incorporate the toxic heav...

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