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168 research outcomes, page 1 of 17
  • publication . Article . Other literature type . Review . 2017
    Open Access English
    Authors:
    Katherine L. Tucker; James P. Sheppard; Richard Stevens; Hayden B. Bosworth; Alfred Bove; Emma P. Bray; Kenneth Earle; Johnson George; Marshall Godwin; Beverly B. Green; ...
    Project: RCUK | PRedicting Out of OFfice ... (MR/K022032/1)

    Background Self-monitoring of blood pressure (BP) appears to reduce BP in hypertension but important questions remain regarding effective implementation and which groups may benefit most. This individual patient data (IPD) meta-analysis was performed to better understan...

  • publication . Article . Review . Other literature type . 2009
    Open Access English
    Authors:
    Luca Salassa;
    Publisher: Royal Society of Chemistry
    Project: RCUK | Photoactivation strategie... (EP/G006792/1), EC | PHOTORUACD (220281)

    The fields of phototherapy and of inorganic chemotherapy both have long histories. Inorganic photoactivated chemotherapy (PACT) offers both temporal and spatial control over drug activation and has remarkable potential for the treatment of cancer. Following photoexcitat...

  • publication . Other literature type . Article . Review . 2012
    Open Access English
    Authors:
    Alistair J P Brown; Leah Cowen; Michelle Leach;
    Project: RCUK | Combinatorial responses o... (BB/F00513X/1), WT | Wellcome Strategic Award ... (097377), EC | FINSYSB (214004), WT | Candida albicans cell sur... (080088), EC | STRIFE (249793), EC | UNICELLSYS (201142), WT | How does the pathogen Can... (096072), RCUK | Role of the Heat Shock Tr... (BB/D009308/1), CIHR

    Hsp90 is an essential, abundant, and ubiquitous eukaryotic chaperone that has crucial roles in protein folding and modulates the activities of key regulators. The fungal Hsp90 interactome, which includes numerous client proteins such as receptors, protein kinases and tr...

  • publication . Article . Other literature type . Review . 2020
    Open Access English
    Authors:
    Oliver Stegle; Maria Florescu; Kieran R Campbell; Davis J. McCarthy; David Laehnemann; Giacomo Corleone; Catalina Vallejos; Mark Robinson; Felix Mölder; Alexander Zelikovsky;
    Project: SNSF | Beyond the average: compu... (310030_175841), NWO | Statistical Models for St... (2300178920), NIH | QuBBD: Viral Evolution an... (1R01EB025022-01), WT , SNSF | Defining the identity and... (CRSII5_177208), NIH | Statistical Methods for t... (4R00HG009007-03), NHMRC | Combining human genetics ... (1112681), EC | EpiPredict (642691), NIH | Discovering disease-causa... (5R00HG008399-04), NSF | CAREER: Algorithms for Ne... (1053753),...

    textabstractThe recent boom in microfluidics and combinatorial indexing strategies, combined with low sequencing costs, has empowered single-cell sequencing technology. Thousands-or even millions-of cells analyzed in a single experiment amount to a data revolution in si...

  • publication . Review . Article . Other literature type . 2010
    Open Access English
    Authors:
    Gary R Mirams; Oliver Jensen; Helen Byrne; Alexander Fletcher; James Osborne; david gavaghan;
    Publisher: ROYAL SOC
    Project: EC | PREDICT (224381), RCUK | Doctoral Training Centre ... (EP/E501605/1), RCUK | New frontiers in the math... (EP/D048400/1), RCUK | From Bacterial Chemotaxis... (BB/D020190/1)

    <jats:p>In this paper, we review multi-scale models of solid tumour growth and discuss a middle-out framework that tracks individual cells. By focusing on the cellular dynamics of a healthy colorectal crypt and its invasion by mutant, cancerous cells, we compare a cell-...

  • publication . Article . Other literature type . Review . 2010
    Open Access English
    Authors:
    Maria Siebes;
    Project: EC | EUHEART (224495), RCUK | New mathematical models f... (EP/D070635/2), RCUK | Modelling the cellular ca... (BB/F01080X/1)

    A key aim of the cardiac Physiome Project is to develop theoretical models to simulate the functional behaviour of the heart under physiological and pathophysiological conditions. Heart function is critically dependent on the delivery of an adequate blood supply to the ...

  • publication . Review . Article . Other literature type . 2017
    Open Access English
    Authors:
    Marucci, Lucia;
    Publisher: Hindawi
    Project: RCUK | BrisSynBio: Bristol Centr... (BB/L01386X/1), RCUK | Unravelling the role of b... (MR/N021444/1)

    Mouse Embryonic Stem Cells (mESCs), derived from the inner cell mass of<br/>the blastocyst, are pluripotent stem cells having self-renewal capability and the<br/>potential of differentiating into every cell type under the appropriate culture<br/>conditions. An increasin...

  • publication . Preprint . Article . Other literature type . Review . 2012
    Open Access English
    Authors:
    Pasquale Di Bari;
    Project: RCUK | Theory and Phenomenology ... (ST/G000557/1), EC | INVISIBLES (289442)

    Comment: 28 pages; 7 figures; invited introductory review to appear in Contemporary Physics

  • publication . Article . Review . 2013
    Open Access
    Authors:
    Andrew B. Cairns;
    Publisher: Royal Society of Chemistry (RSC)
    Project: RCUK | Local Structure and Dynam... (EP/G004528/2), EC | NANOSTRUCTURE (279705), EC | COMETHY (279075)

    It is increasingly apparent that many important classes of molecular framework material exhibit a variety of interesting and useful types of structural disorder. This tutorial review summarises a number of recent efforts to understand better both the complex microscopic...

  • publication . Review . Other literature type . Article . 2011
    Open Access English
    Authors:
    Shona Wood; Michael Plank; Joao Pedro de Magalhaes;
    Publisher: AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS
    Project: RCUK | Using massive-scale mRNA ... (BB/H008497/1)

    Aging is the major biomedical challenge of this century. The percentage of elderly people, and consequently the incidence of age-related diseases such as heart disease, cancer, and neurodegenerative diseases, is projected to increase considerably in the coming decades. ...

168 research outcomes, page 1 of 17
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