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23,355 research outcomes, page 1 of 2,336
  • publication . Article . Other literature type . 2015
    Open Access English
    Authors:
    Cristiano Scottá; Niloufar Safinia;
    Publisher: Frontiers Media S.A.
    Project: RCUK | MRC Centre for Transplant... (MR/J006742/1)

    Regulatory T cells (Tregs) play an important role in immunoregulation and have been shown in animal models to promote transplantation tolerance and curb autoimmunity following their adoptive transfer. The safety and potential therapeutic efficacy of these cells has alre...

  • publication . Article . Other literature type . 2020
    Open Access
    Authors:
    Buchmann, Jens; Kaplan, Bernhard; Powell, Samuel; Prohaska, Steffen; Laufer, Jan;
    Publisher: Elsevier BV
    Project: RCUK | Tomographic imaging of fl... (EP/N032055/1)

    Quantitative photoacoustic tomography aims to recover the spatial distribution of absolute chromophore concentrations and their ratios from deep tissue, high-resolution images. In this study, a model-based inversion scheme based on a Monte-Carlo light transport model is...

  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Kaitlin H. Wade; A. Mesut Erzurumluoglu; Alun Hughes; Abigail Fraser; Evangelia Stergiakouli; Laura Howe; George Davey Smith; Linda O'Keeffe; Emma L Anderson; Debbie Lawlor;
    Publisher: Elsevier BV
    Project: RCUK | Statistics and Econometri... (MC_UU_12013/9), RCUK | Understanding gender diff... (MR/M014509/1), RCUK | Integrative epidemiology ... (MC_UU_12013/5), RCUK | Mediation analysis in lif... (MR/M020894/1), RCUK | Life course epidemiology ... (MR/M009351/1), RCUK | Enhancing the MRC Nationa... (MC_UU_12019/1), WT | Early Life determinants o... (086676), RCUK | Determinants, Consequence... (MC_UU_12013/6)

    Highlights • Common Y chromosomal haplogroups are not associated with cardiometabolic risk factors from birth to age 18. • Common Y chromosomal haplogroups are not associated with cardiovascular structure and function at age 18. • Common Y chromosomal haplogroups are no...

  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    Daversa, DR; Fenton, A; Dell, AI; Garner, TWJ; Manica, Andrea;
    Publisher: The Royal Society
    Project: RCUK | Quantifying host species ... (NE/N009967/1), RCUK | Quantifying host species ... (NE/N009800/1)

    Animal movement impacts the spread of human and wildlife diseases, and there 27 is significant interest in understanding the role of migrations, biological 28 invasions, and other wildlife movements in spatial infection dynamics. However, 29 the influence of processes d...

  • publication . Article . Preprint . Other literature type . 2016
    Open Access
    Authors:
    Marcus Munafo; David Evans; George Davey Smith;
    Publisher: Oxford University Press (OUP)
    Project: RCUK | Statistics and Econometri... (MC_UU_12013/9), RCUK | Accessible resource for i... (BB/I025263/1), WT | The Avon Longitudinal Stu... (102215), RCUK | Data mining and bioinform... (MC_UU_12013/8), RCUK | Using Genetics to Identif... (MC_UU_12013/4), WT , RCUK | From Mendelian Randomizat... (MC_UU_12013/1), RCUK | Determinants, Consequence... (MC_UU_12013/6), RCUK | Epigenetic Epidemiology (MC_UU_12013/2)

    <jats:title>Abstract</jats:title><jats:p>Large-scale cross-sectional and cohort studies have transformed our understanding of the genetic and environmental determinants of health outcomes. However, the representativeness of these samples may be limited – either through ...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Ji-Hwan Lee; Aloysius Soon; Young-Kwang Jung; Aron Walsh;
    Publisher: American Chemical Society
    Project: RCUK | Energy Materials: Computa... (EP/K016288/1), EC | HYBRIDS (277757)

    CsSnI3 is a potential lead-free inorganic perovskite for solar energy applications due to its nontoxicity and attractive optoelectronic properties. Despite these advantages, photovoltaic cells using CsSnI3 have not been successful to date, in part due to low stability. ...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Susumu SAITO; Kellie Jenkinson; Hiroshi Naka;
    Publisher: Nature Publishing Group UK
    Project: RCUK | DTA - University of Cambr... (EP/J500380/1)

    Direct functionalization of amino groups in complex organic molecules is one of the most important key technologies in modern organic synthesis, especially in the synthesis of bio-active chemicals and pharmaceuticals. Whereas numerous chemical reactions of amines have b...

  • publication . Other literature type . Article . 2015
    Open Access
    Authors:
    Abigail Perrin; Gavin J. Wright; Moritz Treeck;
    Publisher: Elsevier BV
    Project: RCUK | Structural changes to hos... (G1100013), WT | Wellcome Trust Sanger Ins... (098051), EC | EVIMALAR (242095)

    Egress from infected RBCs is a critical, but poorly understood, step in the malaria parasite’s lifecycle. Das et al. report that just prior to egress, proteolytic processing of parasite surface protein MSP1 activates a spectrin binding function, allowing the intracellul...

  • publication . Article . Other literature type . 2016
    Open Access
    Authors:
    Juan David Martinez-Vargas;
    Publisher: Frontiers Media SA
    Project: WT , RCUK | Building multi-site clini... (MR/K005464/1), RCUK | Non-invasive laminar elec... (BB/M009645/1)

    We demonstrate a method to estimate key electrophysiological parameters from resting state data. In this paper we focus on the estimation of head-position parameters. The recovery of these parameters is especially challenging as they are non-linearly related to the meas...

  • publication . Other literature type . Article . 2015
    Open Access
    Authors:
    Rachael Wilkinson; Peter L. Roach; Neil Wells;
    Publisher: Portland Press Ltd.
    Project: RCUK | Core Capability for Chemi... (EP/K039466/1)

    The bacterial stringent response is induced by nutrient deprivation and is mediated by enzymes of the RSH (RelA/SpoT homologue; RelA, (p)ppGpp synthetase I; SpoT, (p)ppGpp synthetase II) superfamily that control concentrations of the ‘alarmones’ (p)ppGpp (guanosine pent...

23,355 research outcomes, page 1 of 2,336
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