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295 research outcomes, page 1 of 30
  • publication . Article . Other literature type . 2010
    Open Access
    Authors:
    Ross McManus; Sarah Hunt; Elvira Grandone; Panos Deloukas; Graham A Heap; Jeffrey Barrett; Katherine Irene Morley; Alexandra Zhernakova; Bozena Cukrowska; Gosia Trynka; ...
    Publisher: Springer Science and Business Media LLC
    Project: WT | Extended genome wide asso... (084743), NWO | Identifying causative cop... (2300159001), NIH | Type 1 Diabetes Genetics ... (1U01DK062418-01), WT | WTCCC2 core activities (085475), RCUK | Functional investigation ... (G0700545), EC | COPACETIC (201379)

    We performed a second-generation genome-wide association study of 4,533 individuals with celiac disease (cases) and 10,750 control subjects. We genotyped 113 selected SNPs with P(GWAS) < 10(-4) and 18 SNPs from 14 known loci in a further 4,918 cases and 5,684 control...

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Piotr Bentkowski; Ben Ashby; Cock van Oosterhout;
    Project: RCUK | From the North Sea to the... (NE/K004530/1), RCUK | Host-parasite coevolution... (NE/N014979/1)

    Mortality has a significant role in prokaryotic ecology and evolution, yet the impact of variations in extrinsic mortality on prokaryotic genome evolution has received little attention. We used both mathematical and agent-based models to reveal how variations in extrins...

  • publication . Article . Preprint . Other literature type . 2017
    Open Access English
    Authors:
    Alessandra Zanichelli; Marco Scodeggio; LUIGI GUZZO; Federico Marulli; Daniela Vergani; Katarzyna Ewa Małek; Angela Iovino; Rita Tojeiro; Enzo Branchini; dario bottini; ...
    Publisher: EDP Sciences
    Project: EC | MDEPUGS (202686), EC | DARKLIGHT (291521), EC | EARLY (268107), RCUK | Survey Cosmology and Astr... (ST/I001204/1), EC | STGDELUCIA2007 (202781)

    We identified voids in the completed VIMOS Public Extragalactic Redshift Survey (VIPERS), using an algorithm based on searching for empty spheres. We measured the cross-correlation between the centres of voids and the complete galaxy catalogue. The cross-correlation fun...

  • publication . Preprint . 2020
    Open Access English
    Authors:
    Ayres, N.J.; Ban, G.; Bison, G.; Bodek, K.; Bondar, V.; Chanel, E.; Chiu, P.-J.; Crawford, C.; Daum, M.; Emmenegger, S.; ...
    Publisher: HAL CCSD
    Project: SNSF | Measurement of the neutro... (200020_162574), SNSF | Precision Physics with Mu... (200020_172639), RCUK | Sussex Experimental Parti... (ST/N000307/1), SNSF | Low Energy Particle Physi... (200021_181996), SNSF | Measurement of the neutro... (200020_149211), RCUK | Training Grant Sussex (ST/M503836/1)

    Psychological bias towards, or away from, a prior measurement or a theory prediction is an intrinsic threat to any data analysis. While various methods can be used to avoid the bias, e.g.\ actively not looking at the result, only data blinding is a traceable and thus tr...

  • publication . Article . 2016
    Open Access English
    Authors:
    A. Matthew Prina;
    Publisher: The Authors. Published by Elsevier B.V.
    Project: EC | MARATONE (316795), RCUK | Exploring frailty, mental... (MR/K021907/1)

    Highlights • Better inductive reasoning was associated with lower severity of depressed affect. • Better inductive reasoning was associated with lower severity of somatic symptoms. • Faster processing speed was associated with lower severity of somatic symptoms. • DIF d...

  • publication . Article . Other literature type . Preprint . 2016
    Open Access
    Authors:
    Olga Sikora; Nic Shannon; Owen Benton;
    Publisher: American Physical Society (APS)
    Project: RCUK | Fractional Charges and Fr... (EP/C539974/1)

    It has been known since the pioneering work of Bernal, Fowler and Pauling that common, hexagonal (Ih) water ice is the archetype of a frustrated material : a proton-bonded network in which protons satisfy strong local constraints - the "ice rules" - but do not order. Wh...

  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Andrzej Grzesik; Daniel Král; László Miklós Lovász;
    Project: EC | LaDIST (648509), RCUK | Analytic methods for larg... (EP/M025365/1), NSF | PostDoctoral Research Fel... (1705204)

    We study the uniqueness of optimal solutions to extremal graph theory problems. Lovasz conjectured that every finite feasible set of subgraph density constraints can be extended further by a finite set of density constraints so that the resulting set is satisfied by an ...

  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Oliver Stegle; Maria Florescu; Kieran R Campbell; Davis J. McCarthy; David Laehnemann; Giacomo Corleone; Catalina Vallejos; Mark Robinson; Felix Mölder; Alexander Zelikovsky;
    Project: NIH | Statistical Methods for t... (4R00HG009007-03), NIH | QuBBD: Viral Evolution an... (1R01EB025022-01), NSF | CAREER: Algorithms for Ne... (1053753), NIH | Discovering disease-causa... (5R00HG008399-04), NWO | Statistical Models for St... (2300178920), SNSF | Defining the identity and... (CRSII5_177208), SNSF | The structure and functio... (310030B_182828), NIH | Computational Characteriz... (7R01HG007069-04), EC | EpiPredict (642691), WT ,...

    textabstractThe recent boom in microfluidics and combinatorial indexing strategies, combined with low sequencing costs, has empowered single-cell sequencing technology. Thousands-or even millions-of cells analyzed in a single experiment amount to a data revolution in si...

  • publication . Article . Preprint . Other literature type . Research . 2019
    Open Access
    Authors:
    Wang, L.; Gao, F.; Duncan, K. J.; Williams, W. L.; Rowan-Robinson, M.; Sabater, J.; Shimwell, T. W.; Bonato, M.; Calistro-Rivera, G.; Chyży, K. T.; ...
    Publisher: EDP Sciences
    Project: RCUK | STFC Hertfordshire 2015 D... (ST/N504105/1), RCUK | Hertfordshire Astronomy 2... (ST/R000905/1), EC | NEWCLUSTERS (321271), RCUK | Astronomy and Astrophysic... (ST/R000972/1), RCUK | Astronomy and Astrophysic... (ST/M001229/1)

    Comment: 13 pages, 13 figures, accepted for publication in A&A

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Deborah JG Mackay; Kemi (Oluwakemi) Lokulo-Sodipe; Michal Patalan; Isabel Karen Temple; Maria Giżewska; Faisal I Rezwan; Emma Wakeling; Julian Hamilton-Shield; Rachel Horton;
    Publisher: BMJ Publishing Group
    Project: WT , RCUK | Identifying factors requi... (MR/J000329/1)

    <jats:sec><jats:title>Background</jats:title><jats:p>Genomic imprinting results from the resistance of germline epigenetic marks to reprogramming in the early embryo for a small number of mammalian genes. Genetic, epigenetic or environmental insults that prevent imprint...

295 research outcomes, page 1 of 30
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