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39 research outcomes, page 1 of 4
  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Albert V Smith; Michele Callisaya; Rebekah McWhirter; Claes Ohlsson; David Karasik; Simon Mooijaart; Velandai Srikanth; Marian Beekman; Jessica Faul; Russell Thomson; ...
    Project: NIH | HEALTH ABC--COORDINATING ... (N01AG062106-019), NIH | Institute for Clinical an... (3UL1RR025005-03S2), NIH | SHORT-TERM STABILITY OF C... (1P30AG010161-01), NIH | CHARGE consortium: gene d... (2R01HL105756-07), NIH | Risk Factors, Pathology, ... (5R01AG015819-07), NIH | OSTEOPOROTIC FRACTURES--V... (3R01AR035584-05S1), NIH | CTSA INFRASTRUCTURE FOR C... (2UL1RR024140-06), EC | IDEAL (259679), NIH | Study of Osteoporotic Fra... (2R01AG027576-22A1), NWO | NCHA Subsidiebesluit 2008... (2300155116),...

    Emerging evidence suggests that the basis for variation in late-life mobility is attributable, in part, to genetic factors, which may become increasingly important with age. Our objective was to systematically assess the contribution of genetic variation to gait speed i...

  • publication . Other literature type . Article . 2013
    Open Access
    Authors:
    Xavier Harrison; Stuart Bearhop; Tom Tregenza; Richard Inger; Kendrew Colhoun;
    Publisher: Public Library of Science (PLoS)
    Project: RCUK | The consequences of seaso... (NE/F021690/1), EC | STATEMIG (310820)

    In many animals, processes occurring in one season carry over to influence reproductive success and survival in future seasons. The strength of such carry-over effects is unlikely to be uniform across years, yet our understanding of the processes that are capable of mod...

  • publication . Article . 2013
    Open Access
    Authors:
    Stefan Enroth; Alex Couto Alves; Ashish Kumar; Ozren Polasek; Caroline Hayward; Eva Reischl; Lorna M Lopez; Gian Andri Thun; Michele Zorzetto; Victoria Jackson; ...
    Publisher: Public Library of Science (PLoS)
    Project: SNSF | SAPALDIA COHORT STUDY: Mo... (32473B-104288), NIH | Genetic Influences on ADH... (1R01MH063706-01), SNSF | Swiss Study on Air Pollut... (3200-042532), NIH | Genetics of cardiovascula... (5R01HL087679-02), SNSF | Swiss Cohort Study on Air... (33CS30_134276), WT | Cambridge Institute for M... (079895), SNSF | Swiss Cohort Study on Air... (33CSC0-108796), SNSF | The SAPALDIA II Cohort St... (3100-059302), SNSF | Swiss Study on Air Pollut... (3200-052720), SNSF | The SAPALDIA II Cohort St... (3247-065896),...

    Author Summary Low levels of alpha1-antitrypsin (AAT) in the blood are a well-established risk factor for accelerated loss in lung function and chronic obstructive pulmonary disease. While a few infrequent genetic polymorphisms are known to influence the serum levels of...

  • publication . Conference object . Article . 2016
    Open Access
    Authors:
    Joanna Martin; Itaru Kushima; Norio Ozaki; Anthony R. Isles; Harry Potter; James Walters; Michael J Owen; Nakao IWATA; Branko Aleksic; Elliott Rees; ...
    Project: NIH | MOLECULAR GENETICS OF SCH... (5R01MH059566-04), NIH | MOLECULAR GENETICS OF SCH... (5R01MH059586-03), NIH | MOLECULAR GENETICS OF SCH... (1R01MH060870-01), NIH | DIAGNOSTIC CENTER FOR LIN... (5U01MH046276-03), NIH | MOLECULAR GENETICS OF SCH... (5R01MH059571-04), EC | EPIPGX (279062), EC | EU-GEI (241909), NIH | Molecular Genetics of Sch... (5R01MH060879-06), NIH | Genome-wide Association S... (5U01MH079470-03), RCUK | Molecular Genetics of Sch... (G0800509),...

    Author Summary The genetic interval 15q11.2-q13.3 on human chromosome 15 contains several so-called “imprinted genes” which are subject to epigenetic marking leading to activity from only one parental copy. This is in contrast to non-imprinted genes, whose activity is i...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Bjarni Bessason; Tiziana Rossetto; ioanna ioannou;
    Publisher: Springer Science and Business Media LLC
    Project: RCUK | The Alan Turing Institute (EP/N510129/1), EC | IMPROVER (653390)

    In June 2000, two Mw6.5 earthquakes occurred within a 4-day interval in the largest agricultural region of Iceland causing substantial damage and no loss of life. The distance between the earthquake epicentres and the fault rupture was approximately 15 km. Nearly 5000 l...

  • publication . Other literature type . Article . 2016
    Open Access
    Authors:
    Paul Halloran; Ian R. Hall;
    Publisher: Springer Science and Business Media LLC
    Project: RCUK | Climate of the LAst Mille... (NE/N001176/1), RCUK | ULTRA-HIGH-RESOLUTION PRO... (NE/H023356/1)

    Owing to the lack of absolutely dated oceanographic information before the modern instrumental period, there is currently significant debate as to the role played by North Atlantic Ocean dynamics in previous climate transitions (for example, Medieval Climate Anomaly-Lit...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Went, Molly; Sud, Amit; Försti, Asta; Halvarsson, Britt-Marie; Weinhold, Niels; Kimber, Scott; Van Duin, Mark; Thorleifsson, Gudmar; Holroyd, Amy; Johnson, David C; ...
    Project: NIH | Imputation-based approach... (7U01CA188392-03), RCUK | Health of vegetarians (MR/M012190/1), NIH | Elucidating Loci Involved... (5U19CA148537-02), WT | Understanding the genetic... (090532), NIH | SCID-hu and In Vivo Model... (5P01CA055819-19), EC | COGS (223175)

    Publisher's version (útgefin grein)

  • publication . Article . Other literature type . 2020
    Open Access English
    Authors:
    Richard J. Allen; Beatriz Guillen-Guio; Justin M. Oldham; Shwu-Fan Ma; Amy Dressen; Megan L. Paynton; Luke M. Kraven; Ma'en Obeidat; Xuan Li; Michael Ng; ...
    Project: NIH | Obstructive Sleep Apnea a... (1R01HL137234-01A1), NIH | UCLA Clinical Translation... (3UL1TR001881-01S2), RCUK | Defining the genetic cont... (G1000861), NIH | Identifying Genetic Deter... (5R01HL113264-04), NIH | SUBCLINICAL CARDIOVASCULA... (N01HC095161-000), NIH | Genetic and Genomic Chara... (1R01HL135142-01A1), NIH | SUBCLINICAL CARDIOVASCULA... (N01HC095164-002), NIH | SUBCLINICAL CARDIOVASCULA... (N01HC095168-000), NIH | SUBCLINICAL CARDIOVASCULA... (N01HC095162-000), NIH | Wake forest Clinical and ... (1UL1TR001420-01),...

    <p>RATIONALE: Idiopathic pulmonary fibrosis (IPF) is a complex lung disease characterised by scarring of the lung that is believed to result from an atypical response to injury of the epithelium. Genome-wide association studies have reported signals of association impli...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Robinson, Sinikka I.; McLaughlin, Órla B.; Marteinsdóttir, Bryndís; O'Gorman, Eoin J.;
    Publisher: John Wiley and Sons Inc.
    Project: RCUK | Impacts of habitat fragme... (NE/L011840/1), RCUK | Impacts of global warming... (NE/M020843/1)

    Publisher's version (útgefin grein)

  • publication . Article . 2015
    Open Access English
    Authors:
    Marie Edmonds; Thor Thordarson; Margaret Hartley; David A. Neave;
    Publisher: Elsevier
    Project: RCUK | Reconstructing magma stor... (NE/I012508/1)

    The pre-eruptive water content of magma is often estimated using crystal-hosted melt inclusions. However, olivine-hosted melt inclusions are prone to post-entrapment modification by H+ diffusion as they re-equilibrate with their external environment. This effect is well...

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