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37 research outcomes, page 1 of 4
  • publication . Article . 2018
    Open Access
    Authors:
    Ziqiang Cheng;
    Publisher: MDPI AG
    Project: RCUK | UK-China partnership on G... (BB/R012865/1)

    Superinfection of Marek’s disease virus (MDV) and avian leukosis virus subgroup J (ALV-J) causes lethal neoplasia and death in chickens. However, whether there is synergism between the two viruses in viral replication and pathogenicity has remained elusive. In this stud...

  • publication . Article . Other literature type . 2015
    Open Access English
    Authors:
    AL-Mashhadani, M.K.H.; Wilkinson, S.J.; Zimmerman, W.B.;
    Publisher: Elsevier
    Project: RCUK | A Coordinated, Comprehens... (EP/K001329/1), RCUK | Microbubble cloud generat... (EP/I019790/1)

    Abstract Airlift bioreactors can provide an attractive alternative to stirred tanks, particularly for bioprocesses with gaseous reactants or products. Frequently, however, they are susceptible to being limited by gas–liquid mass transfer and by poor mixing of the liquid...

  • publication . Article . 2018
    Open Access English
    Authors:
    Armitage, Emily G.; Alqaisi, Amjed Q.I.; Godzien, Joanna; Peña, Imanol; Mbekeani, Alison J.; Alsonso-Herranz, Vanesa; López-Gonzálvez, Ángeles; Martín, Julio; Gabarro, Raquel; Denny, Paul W.; ...
    Publisher: American Society for Microbiology
    Project: RCUK | Sphingolipid biosynthesis... (BB/M024156/1), WT | Wellcome Trust Centre for... (104111), RCUK | A Global Network for Negl... (MR/P027989/1)

    ABSTRACT With the World Health Organization reporting over 30,000 deaths and 200,000 to 400,000 new cases annually, visceral leishmaniasis is a serious disease affecting some of the world's poorest people. As drug resistance continues to rise, there is a huge unmet need...

  • publication . Other literature type . Article . Preprint . 2019
    Open Access
    Authors:
    Tomlinson, Sean; Yates, Henrietta C.; Oruni, Ambrose; Njoroge, Harun; Weetman, David; Donnelly, Martin J.; Van’t Hof, Arjen E;
    Publisher: bioRxiv
    Project: NIH | Genome-based diagnostics ... (5R01AI116811-02), RCUK | Using spatial statistics ... (MR/P02520X/1), RCUK | Adaptive introgression in... (1855159)

    Background\ud Malaria vector control and research rely heavily on monitoring mosquito populations for the development of resistance to public health insecticides. One standard method for determining resistance in adult mosquito populations is the World Health Organizati...

  • publication . Article . Conference object . 2016
    Open Access English
    Authors:
    Julian Thorpe; Dr Youssra Al-Hilaly; Louise Serpell; Wei-Feng Xue;
    Publisher: Nature Publishing Group
    Project: RCUK | Quantitative investigatio... (BB/J008001/1)

    Parkinson’s disease (PD) is characterized by intracellular, insoluble Lewy bodies composed of highly stable α-synuclein (α-syn) amyloid fibrils. α-synuclein is an intrinsically disordered protein that has the capacity to assemble to form β-sheet rich fibrils. Oxidiative...

  • publication . Article . Conference object . Other literature type . 2016
    Open Access English
    Authors:
    Al-mashhadani, M.K.H.; Wilkinson, S.J.; Zimmerman, W.B.;
    Publisher: Elsevier
    Project: RCUK | A Coordinated, Comprehens... (EP/K001329/1), RCUK | Microbubble cloud generat... (EP/I019790/1)

    AbstractThis paper addresses the use of anaerobic bacteria to convert carbon dioxide to biomethane as part of the biodegradation process of organic waste. The current study utilises gaslift bioreactors with microbubbles generated by fluidic oscillation to strip the meth...

  • publication . Article . Conference object . 2017
    Open Access English
    Authors:
    J.Rafael Ciges-Tomas; Ignacio Mir Sanchis; José R Penadés; Maan M Neamah; Janine Bowring; Marina, A.;
    Publisher: eLife Sciences Publications, Ltd
    Project: RCUK | Molecular biology of the ... (MR/M003876/1), EC | DUT-signal (670932), EC | BIOSTRUCT-X (283570), WT | Understanding bacterial h... (201531), RCUK | Understanding a novel mec... (BB/N002873/1)

    Targeting conserved and essential processes is a successful strategy to combat enemies. Remarkably, the clinically important Staphylococcus aureus pathogenicity islands (SaPIs) use this tactic to spread in nature. SaPIs reside passively in the host chromosome, under the...

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Ahmed M Sadoon; Ethan Cunningham; Jonathan Tandy;
    Publisher: American Chemical Society
    Project: RCUK | DTA - University of Notti... (EP/L50502X/1)

    Infrared (IR) spectra of complexes between NaCl and methanol have been recorded for the first time. These complexes were formed in liquid helium nanodroplets by consecutive pick-up of NaCl and CH3OH molecules. For the smallest NaCl(CH3OH)n, complexes where n = 1−3, the ...

  • publication . Article . 2017
    Open Access English
    Authors:
    Al-Ameri, Talib; Georgiev, V.P.; Adamu-Lema, F.; Asenov, Asen;
    Publisher: IEEE
    Project: RCUK | Quantum Electronics Devic... (EP/P009972/1)

    In this paper we present a simulation study of vertically stacked lateral nanowires transistors (NWTs), which may have applications at 5nm CMOS technology. Our simulation approach is based on a collection of simulation techniques to capture the complexity in such ultra-...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Andrew Bottrill; Martin Cohen-Gonsaud; Philippe Barthe; Patrick Moynihan; Galina Mukamolova; Russell Wallis;
    Publisher: HAL CCSD
    Project: RCUK | MOLECULAR BASIS OF PKNB E... (BB/P001513/1), RCUK | Breaking the walls to wak... (BB/H008586/1), RCUK | Nothing wasted: Peptidogl... (BB/N011945/1), RCUK | Molecular Basis of PKNB E... (BB/P001289/1)

    Highlights • PknB is not critical for M. tuberculosis growth in osmoprotective medium • CwlM is the major substrate of PknB • Phosphorylation controls localization of CwlM in the cytoplasmic and membrane fractions • Phospho-CwlM binds FhaA, and non-phospho-CwlM interact...

37 research outcomes, page 1 of 4
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