Filters (3 )
Download Results
68 research outcomes, page 1 of 7
  • publication . Article . Preprint . Other literature type . 2017
    Open Access
    Authors:
    Adam Deller; Ray Norris; Ivan Delvecchio;
    Publisher: EDP Sciences
    Project: RCUK | Astronomy and Astrophysic... (ST/M001229/1), EC | COSMASS (337595)

    Comment: 19 pages, 15 figures, 5 tables. Accepted for publication in A&A

  • publication . Article . 2011
    Open Access English
    Authors:
    Chris Haley; Caroline Hayward; Wenhua Wei; Malcolm Dunlop; Andrew Hicks; Gibran Hemani; Pau Navarro;
    Publisher: Public Library of Science
    Project: WT , RCUK | Epicluster: A novel tool ... (BB/H024484/1)

    <p>Genome-wide association (GWA) studies have identified a number of loci underlying variation in human serum uric acid (SUA) levels with the SLC2A9 gene having the largest effect identified so far. Gene-gene interactions (epistasis) are largely unexplored in these GWA ...

  • publication . Article . Preprint . Other literature type . 2018
    Open Access English
    Authors:
    Swagata Halder; Ignacio Torrecilla; Martin D. Burkhalter; Marta Popović; John Fielden; Bruno Vaz; Judith Oehler; Domenic Pilger; Davor Lessel; Katherine Wiseman; ...
    Publisher: Nature Publishing Group
    Project: RCUK | Molecular insights into u... (MC_EX_MR/K022830/1)

    The SPRTN metalloprotease is essential for DNA-protein crosslink (DPC) repair and DNA replication in vertebrate cells. Cells deficient in SPRTN protease exhibit DPC-induced replication stress and genome instability, manifesting as premature ageing and liver cancer. Here...

  • publication . Preprint . 2018
    Open Access
    Authors:
    Powell, Timothy R.; Gaspar, Helena; Chung, Raymond; Keohane, Aoife; Gunasinghe, Cerisse; Uher, Rudolf; Aitchison, Katherine J.; Souery, Daniel; Mors, Ole; Maier, Wolfgang; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: CIHR , RCUK | A multi-omic approach to ... (MR/N014863/1)

    <jats:title>Abstract</jats:title><jats:p>Inflammatory markers such as cytokines represent potential biomarkers for major depressive disorder (MDD). Many, generally small studies have examined the role of single markers and found significant associations. We assessed 42 ...

  • publication . Article . 2012
    Open Access English
    Authors:
    Kai A. Kropp; Hille Tekotte; Ana Angulo; Iain Fraser; Martin Messerle; Manfred Auer; Peter Ghazal; Stipan Jonjic; Vanda Juranic Lisnic; Matthias J. Reddehase;
    Publisher: Public Library of Science
    Project: WT | Molecular determinants of... (066784), EC | SCG (233457), RCUK | Centre for Systems Biolog... (BB/D019621/1)

    Little is known about the role of viral genes in modulating host cytokine responses. Here we report a new functional role of the viral encoded IE1 protein of the murine cytomegalovirus in sculpting the inflammatory response in an acute infection. In time course experime...

  • publication . Article . Other literature type . Preprint . 2019
    Open Access English
    Authors:
    Elaine Nochefranca Zosa; MARCO NOTARO; Robert Hoehndorf; C. O'Donovan; Daniel B Roche; Jianlin Cheng; Alexandre Renaux; Christophe Dessimoz; José María Fernández González; Peter Rose; ...
    Publisher: HAL CCSD
    Project: RCUK | New Developments of Large... (BB/L020505/1), NIH | Building a unified framew... (1R35GM128637-01), NSF | Bilateral BBSRC-NSF/BIO C... (1458390), AKA | Action on Human Surfaces:... (292589), RCUK | SUPERFAMILY (BB/N019431/1), NIH | Laying the Foundation of ... (2R01GM060595-14), NIH | Integrated Prediction of ... (5R01GM093123-02), NIH | I-TASSER based atomic-lev... (1R01GM083107-01A1), NSF | III: Medium: Collaborativ... (1763246), RCUK | Development of a graph-th... (BB/F00964X/1),...

    National Science FoundationNational Science Foundation (NSF) [DBI1564756, DBI-1458359, DBI-1458390, DMS1614777, CMMI1825941, NSF 1458390]; Gordon and Betty Moore FoundationGordon and Betty Moore Foundation [GBMF 4552]; National Institutes of Health NIGMSUnited States De...

  • publication . Article . 2015
    Open Access English
    Authors:
    Stephen High; Pawel Leznicki; Koraljka Husnjak; Ivan Dikic; Jelena Korac Prlic;
    Publisher: The Company of Biologists
    Project: WT | Tail-anchored protein bio... (092107), RCUK | The structure and functio... (BB/L006510/1), EC | UPSTREAM (290257)

    Highlighted Article: Binding of SGTA to the proteasome delays substrate degradation, thereby providing a mechanism for potentially viable proteins to be rescued for reuse.

  • publication . Article . 2012
    Open Access English
    Authors:
    Thomas Michael Palmer; Evropi Theodoratou; George Davey Smith; Malcolm Dunlop; Lina Zgaga;
    Publisher: Public Library of Science
    Project: WT , RCUK | Centre for molecular-base... (G0600705), NIH | Transdisciplinary Studies... (1U19CA148107-01)

    Vitamin D deficiency has been associated with several common diseases, including cancer and is being investigated as a possible risk factor for these conditions. We reported the striking prevalence of vitamin D deficiency in Scotland. Previous epidemiological studies ha...

  • publication . Article . Preprint . 2019
    Open Access Croatian
    Authors:
    Siddarth Koduru Joshi; Djeylan Aktas; Sören Wengerowsky; Martin Lončarić; Sebastian Philipp Neumann; Bo Liu; Thomas Scheidl; Guillermo Currás Lorenzo; Željko Samec; Laurent Kling; ...
    Publisher: American Association for the Advancement of Science: Science Advances
    Project: RCUK | The EPSRC Quantum Communi... (EP/T001011/1), RCUK | Quantum Technology Capita... (EP/N015126/1), EC | QCALL (675662)

    Comment: 16 pages, 9 figures, 3 tables. Corrected typos, updated references

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Dorian Fuller;
    Publisher: HAL CCSD
    Project: RCUK | The impact of evolving of... (NE/K003402/1)

    We report a successful extraction and sequencing of ancient DNA from carbonized rice grains (Oryza sativa) from six archaeological sites, including two from India and four from Thailand, ranging in age from ca. 2500 to 1500 BP. In total, 221 archaeological grains were p...

68 research outcomes, page 1 of 7
Last index information