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48,161 research outcomes, page 1 of 4,817
  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    Gurdeep S. Mannu; Emma J. Groen; Zhe Wang; Michael Schaapveld; Esther H. Lips; Monica Chung; Ires Joore; Flora E. van Leeuwen; Hendrik J. Teertstra; Gonneke A. O. Winter-Warnars; ...
    Publisher: Springer Science and Business Media LLC
    Project: RCUK | Assessment of the benefit... (MC_U137686858)

    Purpose The future of non-operative management of DCIS relies on distinguishing lesions requiring treatment from those needing only active surveillance. More accurate preoperative staging and grading of DCIS would be helpful. We identified determinants of upstaging preo...

  • publication . Article . 2013
    Open Access English
    Authors:
    Witham, James; Ouboussad, Lylia; Lefevre, Pascal F.;
    Publisher: Public Library of Science (PLoS)
    Project: RCUK | Role of noncoding RNA in ... (BB/G001391/1), RCUK | Functional analysis of th... (G0801215), WT

    The transcriptional activation of the chicken lysozyme gene (cLys) by lipopolysaccharide (LPS) in macrophages is dependent on transcription of a LPS-Inducible Non-Coding RNA (LINoCR) triggering eviction of the CCCTC-binding factor (CTCF) from a negative regulatory eleme...

  • publication . Article . Preprint . Other literature type . 2019
    Open Access
    Authors:
    Hoare, Ben; Levine, Nat; Tseytlin, Arkady A;
    Publisher: IOP Publishing
    Project: RCUK | M-Theory, Cosmology and Q... (ST/P000762/1), EC | GAUGEGRAVSYM (615203)

    Motivated by the search for new integrable string models, we study the properties of massless tree-level S-matrices for 2d sigma models expanded near the trivial vacuum. We find that, in contrast to the standard massive case, there is no apparent link between massless S...

  • publication . Article . 2013
    Open Access
    Authors:
    Jon Timmis; Richard Williams;
    Publisher: Springer Science and Business Media LLC
    Project: RCUK | CoSMoS: Complex Systems M... (EP/E053505/1), RCUK | IDEAS Factory - Resilient... (EP/I005943/1), EC | COCORO (270382)

    Background Experimental autoimmune encephalomyelitis has been used extensively as an animal model of T cell mediated autoimmunity. A down-regulatory pathway through which encephalitogenic CD4Th1 cells are killed by CD8 regulatory T cells (Treg) has recently been propose...

  • publication . Article . Other literature type . Conference object . 2018
    Open Access English
    Authors:
    Jamie Anderson; Jack Benton; Sarah Cotterill;
    Project: RCUK | 'Green infrastructure and... (NE/N013530/1), RCUK | North West Social Science... (ES/P000665/1)

    Background Creating or improving urban green space has the potential to be an effective, sustainable and far-reaching way to increase physical activity and improve other aspects of wellbeing in the population. However, there is a dearth of well-conducted natural experim...

  • publication . Other literature type . Article . 2019 . Embargo End Date: 31 Jan 2019
    Open Access
    Authors:
    Alisic, Laura; Rudge, John; Katz, RF; Wells, Garth; Rhebergen, S;
    Publisher: Apollo - University of Cambridge Repository
    Project: RCUK | Computational tools for m... (NE/I023929/1)

    Conservation laws that describe the behavior of partially molten mantle rock have been established for several decades, but the associated rheology remains poorly understood. Constraints on the rheology may be obtained from recently published experiments involving defor...

  • publication . Preprint . 2019
    Open Access English
    Authors:
    Hermans, Rodolfo I.; Shams, Haymen; Seddon, James P.; Seeds, Alwyn J.; Aeppli, Gabriel;
    Project: RCUK | COherent Terahertz System... (EP/J017671/1), RCUK | HyperTerahertz - High pre... (EP/P021859/1)

    High resolution (900 Hz full-width at half maximum) frequency domain spectroscopy near 0.2Terahertz is achieved using an exact frequency spacing comb-source in the optical communications band, filtering and photo-mixing in a custom Uni-Travelling-Carrier Photodiode (UTC...

  • publication . Other literature type . Article . Conference object . 2018 . Embargo End Date: 15 Jul 2019
    Open Access
    Authors:
    Schoenfelder, Stefan; Mifsud, Borbala; Senner, Claire Elizabeth; Todd, Christopher D; Chrysanthou, Stephanie; Darbo, Elodie; Hemberger, Myriam; Branco, Miguel R;
    Publisher: Apollo - University of Cambridge Repository
    Project: WT | Epigenetic control of ret... (101225), WT , RCUK | MICA: Medical Bioinformat... (MR/L016311/1)

    The role of the genome structure in the establishment of the embryonic and trophoblast lineages is still not well understood. Here the authors perform promoter capture Hi-C in mouse trophoblast and embryonic stem cells and find divergent networks of repressive and activ...

  • publication . Preprint . Article . 2017
    Open Access English
    Authors:
    S. Alex Rautu; George Rowlands; Matthew S. Turner;
    Project: RCUK | Mixed and active membrane... (EP/I005439/1)

    Comment: 5 pages, 4 figures

  • publication . Article . Conference object . Other literature type . 2017
    Open Access English
    Authors:
    Lachlan Coin; Mika Ala-Korpela;
    Publisher: Springer Nature
    Project: AKA | Well-being and health: Re... (104781), RCUK | Centre for molecular-base... (G0600705), AKA | GENETIC REGULATION OF THE... (120315), RCUK | The central role for andr... (G0802782), EC | EURHEALTHAGEING (277849), AKA | Improved methods of lifes... (129269)

    Background: Polycystic ovary syndrome (PCOS) is a common reproductive disorder associated with metabolic disturbances including obesity, insulin resistance and diabetes mellitus. Here we investigate whether changes in the metabolic profile of PCOS women are driven by in...

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