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2,369 research outcomes, page 1 of 237
  • publication . Article . 2011
    Open Access English
    Authors:
    Audun Osland Vik-Mo; Miguel López; Antonio Vidal-Puig;
    Publisher: Springer-Verlag
    Project: RCUK | Lipotoxicity, the link be... (G0802051), EC | OBERSTRESS (281854), EC | REPROBESITY (223713), WT | The Cambridge/Oxford Inte... (065326)

    Objective This study aims to investigate whether orexigenic antipsychotic drugs may induce dyslipidemia and glucose disturbances in female rats through direct perturbation of metabolically active peripheral tissues, independent of prior weight gain. Methods In the curre...

  • publication . Article . Conference object . 2016
    Open Access English
    Authors:
    Stephen Furber; Anders Lansner;
    Publisher: Frontiers Media S.A.
    Project: EC | HBP (604102), EC | BRAINSCALES (269921), EC | BIMPC (320689), RCUK | Biologically-Inspired Mas... (EP/G015775/1), RCUK | Biologically-Inspired Mas... (EP/G015740/1)

    SpiNNaker is a digital, neuromorphic architecture designed for simulating large-scale spiking neural networks at speeds close to biological real-time. Rather than using bespoke analog or digital hardware, the basic computational unit of a SpiNNaker system is a general-p...

  • publication . Article . Preprint . 2016
    Open Access
    Authors:
    Alan Heavens;
    Publisher: IOP Publishing
    Project: RCUK | Astrophysics and Cosmolog... (ST/L000652/1)

    Lensing of the Cosmic Microwave Background (CMB) changes the morphology of pattern of temperature fluctuations, so topological descriptors such as Minkowski Functionals can probe the gravity model responsible for the lensing. We show how the recently introduced two-to-t...

  • publication . Article . Conference object . Other literature type . 2016
    Open Access English
    Authors:
    Stephen J Ormerod; Samraat Pawar;
    Publisher: The Royal Society
    Project: RCUK | Can metabolic traits limi... (NE/M004740/1), RCUK | The influence of major FL... (NE/E004539/1), RCUK | Evolution of NITrogen BUF... (NE/G016917/1), RCUK | Assessing the effects of ... (NE/M017478/1)

    <jats:p> Most research on the effects of environmental change in freshwaters has focused on incremental changes in average conditions, rather than fluctuations or extreme events such as heatwaves, cold snaps, droughts, floods or wildfires, which may have even more profo...

  • publication . Article . Preprint . Other literature type . 2018
    Open Access
    Authors:
    Marcus Munafo; George Davey Smith;
    Publisher: Oxford University Press (OUP)
    Project: RCUK | From Mendelian Randomizat... (MC_UU_12013/1), RCUK | Determinants, Consequence... (MC_UU_12013/6)

    <p>Background: Lower educational attainment is associated with increased rates of smoking, but ascertaining causality is challenging. We used two-sample Mendelian randomization (MR) analyses of summary statistics to examine whether educational attainment is causally rel...

  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Lavinia Spain; JI Lopez; Aengus Stewart; Charles Swanton; Mickael Escudero; Orsolya Pipek; Peter Van Loo; Zoltan Szallasi; Stuart Horswell; Thomas Mitchell; ...
    Publisher: Elsevier BV
    Project: RCUK | MICA: Medical Bioinformat... (MR/L016311/1), WT | The role of 3' UTR variat... (103760), WT | CHARACTERISATION AND ANAL... (088340), RCUK | Lethal renal cell carcino... (MR/P014712/1)

    A multi-center prospective study on 101 patients with clear-cell renal cell carcinoma resolves the evolutionary features and subtypes underpinning the diverse clinical phenotypes of the disease and suggests these features as potential biomarkers for guiding intervention...

  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Ross, Lisa L.; Walker, A. Sarah; Lou, Yu; Tenorio, Allan R.; Gibb, Diana M.; Double, Julia; Gilks, Charles; McCoig, Cynthia C.; Munderi, Paula; Musoro, Godfrey; ...
    Publisher: Public Library of Science (PLoS)
    Project: RCUK | A randomised trial of mon... (G0600344)

    A retrospective analysis of the randomized controlled DART (Development of AntiRetroviral Therapy in Africa; ISRCTN13968779) trial in HIV-1-positive adults initiating antiretroviral therapy with co-formulated zidovudine/lamivudine plus either tenofovir, abacavir, or nev...

  • publication . Article . Other literature type . Conference object . 2019
    Open Access English
    Authors:
    C. J. Tollerton; J. Bohn; T. J. Constant; S. A. R. Horsley; D. E. Chang; E. Hendry; D. Z. Li;
    Publisher: Nature Publishing Group UK
    Project: EC | GRASP (613024), RCUK | &quot;Graphene nanophoton... (EP/K041215/1)

    Abstract Graphene, despite its centrosymmetric structure, is predicted to have a substantial second order nonlinearity, arising from non-local effects. However, there is disagreement between several published theories and experimental data. Here we derive an expression ...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Claudia Langenberg; Michael Sweeting; Heinz Freisling; Elio Riboli; Ann-Sofie Forslund; Camille Lassale; Kim Overvad; Ioanna Tzoulaki; calogero saieva; Claudia Agnoli; ...
    Project: RCUK | Study of the interplay of... (G0800270), RCUK | Aetiology of type 2 diabe... (MC_UU_12015/1), EC | EPIC-CVD (279233), EC | EPICHEART (268834), RCUK | Large-scale integrative s... (MR/L003120/1), RCUK | Nutritional epidemiology (MC_UU_12015/5)

    <p>OBJECTIVE:To investigate the association between alcohol consumption (at baseline and over lifetime) and non-fatal and fatal coronary heart disease (CHD) and stroke.</p> <p>DESIGN:Multicentre case-cohort study.</p> <p>SETTING:A study of cardiovascular disease (CVD) d...

  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Renato Alves; Shinichi Sunagawa; Falk Hildebrand; Kiran Raosaheb Patil; Mechthild Lütge; Sebastian M. Waszak; Martin Thomas Jahn;
    Project: SNSF | Integrative analysis of g... (P2ELP3_155365), EC | MicrobioS (669830), EC | DD-DeCaF (686070), RCUK | Evolution and genetics of... (NE/N013832/1), EC | PopMet (660375), WT

    <jats:sec><jats:title>Objective</jats:title><jats:p>The composition of the healthy human adult gut microbiome is relatively stable over prolonged periods, and representatives of the most highly abundant and prevalent species have been cultured and described. However, mi...

2,369 research outcomes, page 1 of 237
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