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606 research outcomes, page 1 of 61
  • publication . Article . Preprint . 2019
    Open Access English
    Authors:
    Javor K. Novev; Amin Doostmohammadi; Andreas Zöttl; Julia M. Yeomans;
    Project: EC | ABIOMATER (665440), RCUK | Developing multiscale mod... (BB/P02386X/1)

    Abstract We use mesoscale simulations to gain insight into the digestion of biopolymers by studying the break-up dynamics of polymer aggregates (boluses) bound by physical cross-links. We investigate aggregate evolution, establishing that the linking bead fraction and t...

  • publication . Article . 2014
    Open Access English
    Authors:
    Flude, Stephanie; Halton, Alison M.; Kelley, Simon P.; Sherlock, Sarah C.; Schwanethal, James; Wilkinson, Camilla M.;
    Project: RCUK | Micrometre to decimetre s... (NE/I016023/1)

    New data from a gem-quality feldspar from Itrongay, Madagascar, record naturally occurring <sup>40</sup>Ar/<sup>39</sup>Ar age profiles which can be numerically modelled by invoking a single diffusion mechanism and show that microtexturally simple crystals are capable o...

  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Lavinia Spain; JI Lopez; Aengus Stewart; Charles Swanton; Mickael Escudero; Orsolya Pipek; Peter Van Loo; Zoltan Szallasi; Stuart Horswell; Thomas Mitchell; ...
    Publisher: Elsevier BV
    Project: WT | CHARACTERISATION AND ANAL... (088340), WT | The role of 3' UTR variat... (103760), RCUK | MICA: Medical Bioinformat... (MR/L016311/1), RCUK | Lethal renal cell carcino... (MR/P014712/1)

    A multi-center prospective study on 101 patients with clear-cell renal cell carcinoma resolves the evolutionary features and subtypes underpinning the diverse clinical phenotypes of the disease and suggests these features as potential biomarkers for guiding intervention...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Kaptoge, Stephen; Pennells, Lisa; De Bacquer, Dirk; Cooney, Marie Therese; Kavousi, Maryam; Stevens, Gretchen; Riley, Leanne Margaret; Savin, Stefan; Khan, Taskeen; Altay, Servet; ...
    Publisher: Elsevier
    Project: RCUK | Large-scale integrative s... (MR/L003120/1), WT

    Background To help adapt cardiovascular disease risk prediction approaches to low-income and middle-income countries, WHO has convened an effort to develop, evaluate, and illustrate revised risk models. Here, we report the derivation, validation, and illustration of the...

  • publication . Preprint . 2019
    Open Access English
    Authors:
    Mider, Marcin; Jenkins, Paul A.; Pollock, Murray; Roberts, Gareth O.; Sørensen, Michael;
    Project: RCUK | EPSRC and MRC Centre for ... (EP/L016710/1), RCUK | Intractable Likelihood: N... (EP/K014463/1), RCUK | New Approaches to Bayesia... (EP/R018561/1)

    Comment: 37 pages, 5 figures

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Isabel Blanco-Penedo; Vera Eory; Pytrik Reidsma; Nicholas John Hutchings; Daniel Sandars; Raffaele Cortignani; Cairistiona Topp;
    Publisher: Elsevier Science
    Project: RCUK | FACCE-JPI Knowledge Hub: ... (BB/N00485X/1), RCUK | FACCE Knowledge Hub: Mode... (BB/K010301/1)

    Modelling is key to adapting agriculture to climate change (CC), facilitating evaluation of the impacts and efficacy of adaptation measures, and the design of optimal strategies. Although there are many challenges to modelling agricultural CC adaptation, it is unclear w...

  • publication . Other literature type . Article . 2014 . Embargo End Date: 29 Sep 2018
    Open Access
    Authors:
    Holmes, Michael V; Dale, Caroline E; Zuccolo, Luisa; Silverwood, Richard J; Guo, Yiran; Ye, Zheng; Prieto-Merino, David; Dehghan, Abbas; Trompet, Stella; Wong, Andrew; ...
    Publisher: Apollo - University of Cambridge Repository
    Project: NIH | CHANGES IN HEALTH: SOCIO-... (5R37AG013196-07), NIH | Epidemiology of Venous Th... (5R01HL059367-10), RCUK | Enhancing the MRC Nationa... (MC_UU_12019/1), NIH | Institute for Clinical an... (3UL1RR025005-03S2), NHMRC | Role of osteoprotegerin i... (279408), NIH | STUDY CORONARY HEART DISE... (N01HC048048-002), NHMRC | Interaction of Angiotensi... (379600), NWO | NCHA Subsidiebesluit 2008... (2300155116), NIH | CORONARY HEART DISEASE RI... (N01HC048047-022), NIH | CORONARY HEART DISEASE AN... (N01HC085082-024),...

    Lista completa dos Autores: Holmes MV, Dale CE, Zuccolo L, Silverwood RJ, Guo Y, Ye Z, Prieto-Merino D, Dehghan A, Trompet S, Wong A, Cavadino A, Drogan D, Padmanabhan S, Li S, Yesupriya A, Leusink M, Sundstrom J, Hubacek JA, Pikhart H, Swerdlow DI, Panayiotou AG, Borin...

  • publication . Conference object . Contribution for newspaper or weekly magazine . 2019
    Open Access English
    Authors:
    Vasileios Lampos;
    Publisher: ACM
    Project: RCUK | i-sense: EPSRC IRC in Agi... (EP/R00529X/1)

    A considerable body of research has demonstrated that online search data can be used to complement current syndromic surveillance systems. The vast majority of previous work proposes solutions that are based on supervised learning paradigms, in which historical disease ...

  • publication . Preprint . Article . Other literature type . 2018
    Open Access English
    Authors:
    John Gracey;
    Project: RCUK | Theoretical Particle Phys... (ST/L000431/1)

    Comment: 16 pages, 4 figures

  • publication . Other literature type . Preprint . Article . 2018
    Open Access
    Authors:
    Alistair Forrest; Andrew Bretherick; Albin Sandelin; Christine A Wells; piero carninci; Timo Lassmann; John Kenneth Baillie; Masayoshi Itoh; Sara Clohisey; Vladimir B Bajic; Vladimir Bajic; ...
    Publisher: Public Library of Science (PLoS)
    Project: RCUK | The impact of host geneti... (BBS/E/D/20231760), NHMRC | A three-tiered strategy t... (1067983), RCUK | Transcriptomes, networks ... (BBS/E/D/20211552), WT | Wellcome Trust Sanger Ins... (098051), EC | DTSSCP (204135), NHMRC | Genomic characterisation ... (597452), NHMRC | Epigenetic regulation of ... (1045991), NIH | Genetic predictors of res... (1U01GM092691-01), NHMRC | The c-type lectin, Mincle... (455947), EC | MODHEP (259743),...

    Author summary We discover that genetic variants associated with specific diseases have more in common with each other than we have previously seen. Specifically, variants associated with the same disease tend to be in parts of the genome that are turned on or off in si...

606 research outcomes, page 1 of 61
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