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1,670 research outcomes, page 1 of 167
  • publication . Article . 2010
    Open Access
    Authors:
    Neale Ridgway; Sangeeta Banerji;
    Publisher: American Society for Cell Biology (ASCB)
    Project: RCUK | Regulatory mechanisms con... (BB/G021163/1), CIHR

    The study identifies a sterol- and oxysterol binding protein (OSBP)-regulated phosphatidylinositol 4-kinase that regulates ceramide transport protein (CERT) activity and sphingomyelin (SM) synthesis. RNA interference silencing experiments identify PI4KIIα; as the mediat...

  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Daniela Annibali; Thilo Dörk; Camilla Krakstad; Stuart MacGregor; Emma Tham; Alexander Hein; Anthony Swerdlow; Dale R Nyholt; Jodie Painter; Tracy O'Mara; ...
    Publisher: Wiley
    Project: NIH | Mayo Clinic SPORE in Ovar... (3P50CA136393-05S1), NHMRC | Statistical Methods and A... (389892), WT | Genome wide association s... (084766), NIH | Breast Cancer Family Regi... (5UM1CA164920-03), NIH | Follow-up of Ovarian Canc... (3U19CA148112-04S1), NHMRC | Molecular Epidemiology of... (400281), NHMRC | Australian Ovarian Cancer... (400413), NHMRC | Genetics of melanoma risk... (389875), NHMRC | Characterising the trajec... (443036), NHMRC | Research Fellowship - Gra... (442915),...

    Epidemiological, biological, and molecular data suggest links between endometriosis and endometrial cancer, with recent epidemiological studies providing evidence for an association between a previous diagnosis of endometriosis and risk of endometrial cancer. We used ge...

  • publication . Article . Other literature type . 2009
    Open Access English
    Authors:
    Panos Deloukas; Ruth Loos; Gregory Livshits; Ines Barroso; Fernando Rivadeneira; Nicole Soranzo; Eleanor Wheeler; Frances Williams;
    Publisher: Public Library of Science (PLoS)
    Project: RCUK | Assessment of biomedical ... (G0000934), WT | A national DNA control se... (068545), CIHR

    Author Summary The first genetic association studies of adult height have confirmed a role of many common variants in influencing human height, but to date, the genetic basis of differences between different skeletal components of height have not been addressed. Here, w...

  • publication . Conference object . Article . Other literature type . 2019
    Open Access
    Authors:
    Roberta Ghidoni; Daniela Galimberti; Rita Guerreiro; Nuria Bargallo; giorgio giaccone; Martina Bocchetta; Carolina Maruta; ALAZNE GABILONDO; Giorgio Giulio Fumagalli; Miguel Castelo-Branco; ...
    Project: WT | Restoring brain function:... (103838), RCUK | Functional Brain Connecti... (G1100464), WT , CIHR

    The presymptomatic phase of neurodegenerative diseases are characterised by structural brain changes without significant clinical features. We set out to investigate the contribution of functional network resilience to preserved cognition in pre-symptomatic genetic fron...

  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Hanckel, Benjamin; Ruta, Danny; Scott, Gwenda; Peacock, Janet L.; Green, Judith;
    Publisher: Springer Science and Business Media LLC
    Project: RCUK | Developing a theory of ch... (MR/R014094/1), CIHR

    Background Existing evidence identifies health benefits for children of additional daily physical activity (PA) on a range of cardiovascular and metabolic outcomes. The Daily Mile (TDM) is a popular scheme designed to increase children’s PA within the school day. Emergi...

  • publication . Article . Conference object . 2019
    Open Access English
    Authors:
    Hannah Durrington; Imran Satia; Robert Maidstone; Kimberley Holt;
    Publisher: Elsevier Inc
    Project: RCUK | Inflammatory therapeutics... (MR/P023576/1), WT | Role of ATP in Chronic Co... (207504), WT | Clock control of inflamma... (107849)
  • publication . Article . Conference object . Other literature type . 2018
    Open Access
    Authors:
    Tom Williams; Adrian B. Hehl; Mark van der Giezen; Ansgar Gruber;
    Publisher: Oxford University Press (OUP)
    Project: WT | Evolution and function of... (078566), RCUK | Rooting the eukaryotic ra... (NE/P00251X/1), WT

    Abstract The establishment of the mitochondrion is seen as a transformational step in the origin of eukaryotes. With the mitochondrion came bioenergetic freedom to explore novel evolutionary space leading to the eukaryotic radiation known today. The tight integration of...

  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    Sovacool, Benjamin; Burke, Matthew; Baker, Lucy; Kotikalapudi, Chaitanya Kumar; Wlokas, Holle;
    Publisher: Elsevier BV
    Project: RCUK | Research Centre on Innova... (EP/K011790/1), SSHRC

    This article explores how concepts from justice and ethics can inform energy decision-making and highlight the moral and equity dimensions of energy production and use. It defines “energy justice” as a global energy system that fairly distributes both the benefits and b...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Debra J. Skene; Han Wang; Eric Zhang; Deborah Bell-Pedersen; Samuel SC Rund; Maria Robles; Tomasz Zieliński; Herman Wijnen; Emi Nagoshi; David Gatfield; ...
    Publisher: Sage Publications Ltd.
    Project: NIH | Role of Clock-Modulating ... (5R01AG045828-02), RCUK | Neurons and biological ti... (MC_U105170643), NSF | A comparative proteomic a... (1456297), NIH | Multiscale Modeling of Ci... (1U01EB022546-01), NIH | Synaptic Microcircuits Co... (5R01NS091070-03), NIH | A Comprehensive Atlas of ... (5R21AR069266-03), NIH | Peptide Modulation of Phy... (5R01GM098931-06), NIH | Circadian regulation of m... (1R01GM111387-01), NIH | Genetic and Molecular Dis... (3R35GM118021-03S1), NIH | Molecular and cellular me... (3R35GM118290-03S1),...

    Genome biology approaches have made enormous contributions to our understanding of biological rhythms, particularly in identifying outputs of the clock, including RNAs, proteins, and metabolites, whose abundance oscillates throughout the day. These methods hold signific...

  • publication . Preprint . 2009
    Open Access English
    Authors:
    Zhang, Jingfu; Ditty, Michael; Burgarth, Daniel; Ryan, Colm A.; Chandrashekar, C. M.; Laforest, Martin; Moussa, Osama; Baugh, Jonathan; Laflamme, Raymond;
    Project: NSERC , RCUK | Thermalisation and Contro... (EP/F043678/1)

    Comment: published in PRA

1,670 research outcomes, page 1 of 167
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