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93 research outcomes, page 1 of 10
  • publication . Article . Preprint . Other literature type . 2020
    Open Access English
    Authors:
    Armstrong, David J; Lopez, Théo A; Adibekyan, Vardan; Booth, Richard; Bryant, Edward M; Collins, Karen A; Deleuil, Magali; Emsenhuber, Alexandre; Huang, Chelsea X; King, George W; ...
    Publisher: Nature Publishing
    Project: RCUK | Irradiated atmospheres of... (ST/R003726/1)

    Comment: Published in Nature. This is a preprint of the article, before minor changes made during the refereeing and editing process. The published PDF is at https://www.nature.com/articles/s41586-020-2421-7 and can be accessed for free by following this link: https://r...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Lavinia Schuler-Faccini; Matteo Fumagalli; William Arias; Desmond Tobin; Paola Everardo; D J Balding; Juan Camilo Chacon-Duque;
    Publisher: Nature Publishing Group
    Project: RCUK | The genetics of human phy... (BB/I021213/1)

    Pigmentation variation in humans is influenced by complex genetic architecture in different populations. Here, the authors perform a genome-wide association analysis involving > 6,000 Latin Americans for pigmentation of skin and eyes, and identify known and novel geneti...

  • publication . Preprint . Article . 2020
    Open Access English
    Authors:
    L J Zenocratti; M E De Rossi; M A Lara-López; T Theuns;
    Project: RCUK | DiRAC: Memory Intensive 2... (ST/R002371/1), RCUK | DiRAC: Memory Intensive 2... (ST/S002502/1)

    The metallicity of star-forming gas in galaxies from the EAGLE simulations increases with stellar mass. Here we investigate whether the scatter around this relation correlates with morphology and/or stellar kinematics. At redshift $z=0$, galaxies with more rotational su...

  • publication . Other literature type . Preprint . Article . 2018
    Open Access
    Authors:
    Stolle, Eckart; Pracana, Rodrigo; Howard, Philip; Paris, Carolina I.; Brown, Susan J.; Castillo-Carrillo, Claudia; Rossiter, Stephen J.; Wurm, Yannick;
    Publisher: bioRxiv
    Project: RCUK | Genome Annotation for the... (BB/K004204/1), RCUK | MidPlus: A Centre of Exce... (EP/K000128/1), RCUK | Behavioural and molecular... (NE/L00626X/1), EC | SOCIAL CHROMOSOME (623713)

    Abstract Long-term suppression of recombination ultimately leads to gene loss, as demonstrated by the depauperate Y and W chromosomes of long-established pairs of XY and ZW chromosomes. The young social supergene of the Solenopsis invicta red fire ant provides a powerfu...

  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Giovanni Bussotti; Mattia Forneris; Anton J. Enright; Eileen Furlong;
    Publisher: Elsevier BV
    Project: RCUK | Computational prediction ... (BB/J01589X/1), EC | CISREGVAR (322851), EC | NCRNASDEVNET (299504)

    Schor et al. identify hundreds of new lncRNAs expressed at specific embryonic stages and in mesoderm. Many have very specific spatiotemporal expression. Deletion of 3 lncRNAs are viable with no obvious phenotypes, even when stressed. Many lncRNAs have strain-specific ex...

  • publication . Article . 2017
    Open Access English
    Authors:
    Lavinia Schuler-Faccini; William Arias;
    Project: RCUK | The genetics of human phy... (BB/I021213/1)

    The expression of facial asymmetries has been recurrently related with poverty and/or disadvantaged socioeconomic status. Departing from the developmental instability theory, previous approaches attempted to test the statistical relationship between the stress experienc...

  • publication . Article . 2017
    Open Access English
    Authors:
    Christopher Kershaw; Paula Portela;
    Project: RCUK | Mapping global mRNA fate:... (BB/N000757/1), RCUK | Fundamental connections b... (BB/K005979/1)

    Cellular responses to stress stem from a variety of different mechanisms, including translation arrest and relocation of the translationally repressed mRNAs to ribonucleoprotein particles like stress granules (SGs) and processing bodies (PBs). Here, we examine the role ...

  • publication . Preprint . Other literature type . 2020
    Open Access
    Authors:
    Pagura, Lucas; Tevere, Evelyn; Merli, Marcelo L.; Cricco, Julia A.;
    Publisher: Cold Spring Harbor Laboratory
    Project: RCUK | A Global Network for Negl... (MR/P027989/1)

    <jats:title>ABSTRACT</jats:title><jats:p>Heme is an essential cofactor for many biological processes in aerobic organisms. Unlike most organisms, which can synthesize it <jats:italic>de novo</jats:italic> through a conserved pathway, the etiological agent of Chagas dise...

  • publication . Article . 2012
    Open Access English
    Authors:
    Gabrielsen, M.; Riboldi-Tunnicliffe, A.; Ibáñez-Shimabukuro, M.; Griffiths, K.; Roe, A.J.; Cooper, A.; Smith, B.; Córsico, B.; Kennedy, M.W.;
    Publisher: Wiley Blackwell Publishing, Inc
    Project: WT , RCUK | A biochemical and molecul... (BB/G011389/1), WT | Structural and biophysica... (083625)

    As-p18 is a fatty-acid-binding protein from the parasitic nematode Ascaris suum. Although it exhibits sequence similarity to mammalian intracellular fatty-acid-binding proteins, it contains features that are unique to nematodes. Crystals were obtained, but initial diffr...

  • publication . Article . 2013
    Open Access English
    Authors:
    Caroline C. Friedel; Peter Ghazal; M.Mar Albà; Mirko Trilling; Nicolas Bellora;
    Project: RCUK | Centre for Systems Biolog... (BB/D019621/1), RCUK | Regulatory role of non-co... (G1002523)

    Interferons (IFN) play a pivotal role in innate immunity, orchestrating a cell-intrinsic anti-pathogenic state and stimulating adaptive immune responses. The complex interplay between the primary response to IFNs and its modulation by positive and negative feedback loop...

93 research outcomes, page 1 of 10
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