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109 research outcomes, page 4 of 11
  • publication . Article . 2012
    Open Access English
    Authors:
    Lindner, Christian; Sigrüner, Alexander; Walther, Franziska; Bogdahn, Ulrich; Couraud, Pierre; Schmitz, Gert; Schlachetzki, Felix;
    Publisher: HAL CCSD
    Project: EC | LIPIDOMICNET (202272)

    International audience; Background<br />Rapid reperfusion following ischemia is the most effective therapy in stroke therapy. However, the success may be compromised by ischemia & reperfusion (I/R) injury and at the human blood-brain barrier (BBB), therefore the effects...

  • publication . Article . 2012
    Open Access English
    Authors:
    Demirkan, A.; van Duijn, C.M.; Ugocsai, P.; Isaacs, A.; Pramstaller, P.P.; Liebisch, G.; Wilson, J.F.; Johansson, A.; Rudan, I.; Aulchenko, Y.S.; ...
    Publisher: Public Library of Science
    Project: EC | LIPIDOMICNET (202272), WT , NWO | Dissecting genetic comple... (2300137747), NWO | Development of algorithms... (1900120079)

    Phospho- and sphingolipids are crucial cellular and intracellular compounds. These lipids are required for active transport, a number of enzymatic processes, membrane formation, and cell signalling. Disruption of their metabolism leads to several diseases, with diverse ...

  • publication . Article . Other literature type . 2014
    Open Access English
    Authors:
    Briand, N.; Prado, C.; Mabilleau, G.; Lasnier, F.; Le Liepvre, X.; Covington, J. D.; Ravussin, E.; Le Lay, S.; Dugail, I.;
    Publisher: American Diabetes Association
    Project: NIH | Core--Molecular Mechanism... (5P30DK072476-05), EC | LIPIDOMICNET (202272)

    Adipocytes specialized in the storage of energy as fat are among the most caveolae-enriched cell types. Loss of caveolae produces lipodystrophic diabetes in humans, which cannot be reversed by endothelial rescue of caveolin expression in mice, indicating major importanc...

  • publication . Article . 2012
    Open Access English
    Authors:
    Wein, Samuel P.; Côté, Richard G.; Dumousseau, Marine; Reisinger, Florian; Hermjakob, Henning; Vizcaíno, Juan A.;
    Publisher: OXFORD UNIV PRESS
    Project: EC | SLING (226073), EC | PROTEOMEXCHANGE (260558), WT | The Proteomics Identifica... (085949), EC | LIPIDOMICNET (202272), EC | PSIMEX (223411)

    The Protein Identifier Cross-Reference (PICR) service is a tool that allows users to map protein identifiers, protein sequences and gene identifiers across over 100 different source databases. PICR takes input through an interactive website as well as Representational S...

  • publication . Article . 2018
    Open Access
    Authors:
    Schmitz, Gerd; Orsó, Evelyn;
    Publisher: Springer Nature
    Project: EC | LIPIDOMICNET (202272)

    Lipoprotein (a) [Lp(a)] is a modified LDL particle with an additional apolipoprotein [apo(a)] protein covalently attached by a thioester bond. Multiple isoforms of apo(a) exist that are genetically determined by differences in the number of Kringle-IV type-2 repeats enc...

  • publication . Article . Other literature type . 2011
    Open Access
    Authors:
    Challa, T. D.; Beaton, N.; Arnold, M.; Rudofsky, G.; Langhans, W.; Wolfrum, C.;
    Publisher: American Society for Biochemistry & Molecular Biology (ASBMB)
    Project: EC | LIPIDOMICNET (202272), EC | ADIPODIF (205641)

    Increased nutrient intake leads to excessive adipose tissue accumulation, obesity, and the development of associated metabolic disorders. How the intestine signals to adipose tissue to adapt to increased nutrient intake, however, is still not completely understood. We s...

  • publication . Article . 2013
    Open Access English
    Authors:
    Stegmaier, Philip; Kel, Alexander; Wingender, Edgar; Borlak, Jürgen;
    Publisher: PUBLIC LIBRARY SCIENCE
    Project: EC | LIPIDOMICNET (202272)

    Algorithmic comparison of DNA sequence motifs is a problem in bioinformatics that has received increased attention during the last years. Its main applications concern characterization of potentially novel motifs and clustering of a motif collection in order to remove r...

  • publication . Article . Review . 2010
    Open Access English
    Authors:
    Briand, Nolwenn; Dugail, Isabelle; Le Lay, Soazig;
    Publisher: HAL CCSD
    Project: EC | LIPIDOMICNET (202272)

    International audience; <p>Caveolae are specialized lipid microdomains, forming small invaginations in the plasma membrane, known to be implicated in multiple functions including lipid storage, cell signaling and endocytosis. Formation of these wide flask-shaped invagin...

  • publication . Other literature type . Article . 2009
    Open Access English
    Authors:
    Chen, Chia-Ching; Yamada, Tetsuji; Chiu, I-Ming; Liu, Yi-Kuen;
    Publisher: Molecular Diversity Preservation International
    Project: EC | LIPIDOMICNET (202272)

    This paper examines the effectiveness of Taiwanese environmental health policies, whose aim is to improve environmental quality by reducing tire waste via the Tire Resource Recovery Program. The results confirm that implemented environmental health policies improve the ...

  • publication . Article . Other literature type . 2014
    Open Access English
    Authors:
    Dönitz, Jürgen; Wingender, Edgar;
    Project: EC | LIPIDOMICNET (202272)

    Background In multicellular organisms, an intercellular signaling network communicates information from the environment or distant tissues to defined target cells. Intercellular signaling (mostly mediated by hormones) can affect the metabolic state and the gene expressi...

109 research outcomes, page 4 of 11
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