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109 research outcomes, page 2 of 11
  • publication . Article . 2013
    Open Access
    Authors:
    Chamulitrat, W.; Liebisch, G.; Xu, W.; Gan-Schreier, H.; Pathil, A.; Schmitz, G.; Stremmel, W.;
    Publisher: American Society for Pharmacology & Experimental Therapeutics (ASPET)
    Project: EC | LIPIDOMICNET (202272)

    Ursodeoxycholyl lysophosphatidylethanolamide (UDCA-LPE) is a hepatoprotectant in inhibiting apoptosis, inflammation, and hyperlipidemia in mouse models of nonalcoholic steatohepatitis (NASH). We studied the ability of UDCA-LPE to inhibit palmitate (Pal)-induced apoptosi...

  • publication . Article . 2012
    Open Access English
    Authors:
    Csordas A; David Ovelleiro; Wang R; Jm, Foster; Ríos D; Ja, Vizcaíno; Hermjakob H;
    Publisher: OXFORD UNIV PRESS
    Project: EC | PROTEOMEXCHANGE (260558), WT | The Proteomics Identifica... (085949), EC | LIPIDOMICNET (202272)

    The PRoteomics IDEntifications (PRIDE) database is a large public proteomics data repository, containing over 270 million mass spectra (by November 2011). PRIDE is an archival database, providing the proteomics data supporting specific scientific publications in a compu...

  • publication . Article . 2011
    Open Access English
    Authors:
    Bettina Meissburger; Jozef Ukropec; Eva Roeder; Nigel Beaton; Matthias Geiger; Daniel Teupser; Burcak Civan; Wolfgang Langhans; Peter P. Nawroth; Daniela Gasperikova; ...
    Publisher: WILEY-BLACKWELL
    Project: EC | LIPIDOMICNET (202272), EC | ADIPODIF (205641)

    Obesity is a well-known risk factor for the development of secondary complications such as type 2 diabetes. However, only a part of the obese population develops secondary metabolic disorders. Here, we identify the transcription factor retinoid-related orphan receptor g...

  • publication . Article . 2009
    Open Access
    Authors:
    Lutter, D.; Langmann, Th.; Ugocsai, P.; Moehle, C.; Seibold, E.; Splettstoesser, W.D.; Gruber, P.; Lang, E.W.; Schmitz, G.;
    Publisher: Elsevier BV
    Project: EC | LIPIDOMICNET (202272)

    The analysis of large-scale gene expression profiles is still a demanding and extensive task. Modern machine learning and data mining techniques developed in linear algebra, like Independent Component Analysis (ICA), become increasingly popular as appropriate tools for ...

  • publication . Article . 2018
    Open Access English
    Authors:
    Teresa Płatek; Evelyn Orso; Barbara Zapała; Anna Polus; Beata Kieć-Wilk; Monika Piwowar; Monika Chojnacka; Urszula Ciałowicz; Małgorzata Malczewska-Malec; Gerd Schmitz; ...
    Project: EC | LIPIDOMICNET (202272)

    Supplemental Digital Content is available in the text

  • publication . Article . 2012
    Open Access
    Authors:
    Reisinger, Florian; Krishna, Ritesh; Ghali, Fawaz; Ríos, Daniel; Hermjakob, Henning; Antonio Vizcaíno, Juan; Jones, Andrew R.;
    Publisher: Wiley
    Project: EC | LIPIDOMICNET (202272), RCUK | Developing proteome-bioin... (BB/G010781/1), EC | PROTEOMEXCHANGE (260558), RCUK | Standards-compliant softw... (BB/H024654/1), WT | The Proteomics Identifica... (085949)

    We present a Java application programming interface (API), jmzIdentML, for the Human Proteome Organisation (HUPO) Proteomics Standards Initiative (PSI) mzIdentML standard for peptide and protein identification data. The API combines the power of Java Architecture of XML...

  • publication . Article . 2015
    Open Access English
    Authors:
    Nahed El-Najjar; Evelyn Orsó; Stefan Wallner; Gerhard Liebisch; Gerd Schmitz;
    Publisher: Public Library of Science
    Project: EC | LIPIDOMICNET (202272)

    Recent developments in lipid mass spectrometry enable extensive lipid class and species analysis in metabolic disorders such as diabesity and metabolic syndrome. The minor plasma lipid class sphingosylphosphorylcholine (SPC) was identified as a ligand for lipid sensitiv...

  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    Tuohetahuntila, Maidina; Molenaar, Martijn R.; Spee, Bart; Brouwers, Jos F.; Wubbolts, Richard; Houweling, Martin; Yan, Cong; Du, Hong; VanderVen, Brian C; Vaandrager, Arie B.; ...
    Publisher: American Society for Biochemistry & Molecular Biology (ASBMB)
    Project: EC | LIPIDOMICNET (202272)

    Activation of hepatic stellate cells (HSCs) is a critical step in the development of liver fibrosis. During activation, HSCs lose their lipid droplets (LDs) containing triacylglycerols (TAGs), cholesteryl esters, and retinyl esters (REs). We previously pro-vided evidenc...

  • publication . Article . 2011
    Open Access English
    Authors:
    Razny, Urszula; Kiec-Wilk, Beata; Wator, Lukasz; Polus, Anna; Dyduch, Grzegorz; Solnica, Bogdan; Malecki, Maciej; Tomaszewska, Romana; Cooke, John P; Dembinska-Kiec, Aldona;
    Project: NIH | Stanford Career Developme... (5K12HL087746-05), NIH | Basic and Translational R... (3U01HL100397-02S1), NIH | NCE-based strategy for nu... (5RC2HL103400-02), NIH | AAA Disease: Mechanism, S... (5P50HL083800-04), EC | LIPIDOMICNET (202272)

    <p>Abstract</p> <p>Background</p> <p>High fat diet impairs nitric oxide (NO) bioavailability, and induces insulin resistance. The link between NO availability and the metabolic adaptation to a high fat diet is not well characterized. The purpose of this study was to inv...

  • publication . Article . 2012
    Open Access English
    Authors:
    Sundelin, Jeanna Perman; Ståhlman, Marcus; Lundqvist, Annika; Levin, Max; Parini, Paolo; Johansson, Martin E.; Borén, Jan;
    Publisher: PUBLIC LIBRARY SCIENCE
    Project: EC | ETHERPATHS (222639), EC | LIPIDOMICNET (202272)

    Clear-cell renal cell carcinoma (RCC) is, in most cases, caused by loss of function of the tumor suppressor gene von Hippel-Lindau, resulting in constitutive activation of hypoxia-inducible factor (HIF)-1 alpha and expression of hypoxia-induced genes in normoxic conditi...

109 research outcomes, page 2 of 11
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