Filters (4)
Download Results
99 research outcomes, page 1 of 10
  • publication . Article . 2016
    Open Access English
    Authors:
    Ai Woon Yee; Martine Moulin; Nina Breteau; Michael Haertlein; Edward P. Mitchell; Jonathan B. Cooper; Elisabetta Boeri Erba; V. Trevor Forsyth;
    Project: UKRI | Deuteration Initiative fo... (EP/C015452/1)

    Abstract It is well established that the formation of transthyretin (TTR) amyloid fibrils is linked to the destabilization and dissociation of its tetrameric structure into insoluble aggregates. Isotope labeling is used for the study of TTR by NMR, neutron diffraction, ...

    Add to ORCIDorcid
  • publication . Article . 2020
    Open Access English
    Authors:
    Odermatt, Nina,; Lelli, Moreno; Herrmann, Torsten; Abriata, Luciano,; Japaridze, Aleksandre; Voilquin, Hubert; Singh, Rajkumar; Piton, Jérémie; Emsley, Lyndon; Dietler, Giovanni; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | iNEXT (653706)

    Abstract In bacteria, nucleoid associated proteins (NAPs) take part in active chromosome organization by supercoil management, three-dimensional DNA looping and direct transcriptional control. Mycobacterial integration host factor (mIHF, rv1388) is a NAP restricted to A...

    Add to ORCIDorcid
  • publication . Article . Other literature type . Preprint . 2021
    Open Access English
    Authors:
    Maryam Alqabandi; N. de Franceschi; Nolwenn Miguet; Sourav Maity; Marta Bally; Wouter H. Roos; Winfried Weissenhorn; Patricia Bassereau; Stéphanie Mangenot;
    Project: ANR | PSL (ANR-10-IDEX-0001), EC | ESCRT model (751715), ANR | ESCRTfission (ANR-14-CE09-0003), EC | INTERACT (751404), ANR | CBH-EUR-GS (ANR-17-EURE-0003)

    Abstract Background ESCRT-III proteins are involved in many membrane remodeling processes including multivesicular body biogenesis as first discovered in yeast. In humans, ESCRT-III CHMP2 exists as two isoforms, CHMP2A and CHMP2B, but their physical characteristics have...

    Add to ORCIDorcid
  • publication . Other literature type . Article . 2018
    Open Access English
    Authors:
    Katharina Weinhäupl; Martha Brennich; Uli Kazmaier; Joël Lelièvre; Lluis Ballell; Alfred L. Goldberg; Paul Schanda; Hugo Fraga;
    Persistent Identifiers
    Publisher: American Society for Biochemistry and Molecular Biology

    Mycobacterium tuberculosis can remain dormant in the host, an ability that explains the failure of many current tuberculosis treatments. Recently, the natural products cyclomarin, ecumicin, and lassomycin have been shown to efficiently kill Mycobacterium tuberculosis pe...

    Add to ORCIDorcid
  • publication . Article . 2020
    Open Access English
    Authors:
    Julia Hennicke; Linda Schwaigerlehner; Clemens Grünwald-Gruber; Isabelle Bally; Wai Li Ling; Nicole M. Thielens; J.-B. Reiser; Renate Kunert;
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)
    Project: ANR | C1qEffero (ANR-16-CE11-0019), ANR | CBH-EUR-GS (ANR-17-EURE-0003), FWF | Biomolecular Technology o... (W 1224)

    International audience; Recombinant production of IgM antibodies poses a special challenge due to the complex structure of the proteins and their not yet fully elucidated interactions with the immune effector proteins, especially the complement system. In this study, we...

    Add to ORCIDorcid
  • publication . Article . 2015
    Open Access
    Authors:
    Fotis ePsomopoulos; Fotis ePsomopoulos; Afonso Miguel Duarte; Christophe eBlanchet; Alexandre M.J.J. Bonvin; Manuel eCorpas; Alain eFranc; Rafael C. Jimenez; Jesus eMarco de Lucas; Tommi eNyrönen; ...
    Project: EC | BIOMEDBRIDGES (284209), AKA | ELIXIR - Data for Life Eu... (273655), WT , FCT | EXPL/BBB-BEP/1356/2013 (134381), EC | EGI-INSPIRE (261323), EC | WENMR (261572), FCT | SFRH/BPD/78075/2011 (SFRH/BPD/78075/2011)

    This is an open-access article.-- et al.

    Add to ORCIDorcid
  • publication . Article . 2015
    Open Access English
    Authors:
    Huaying Zhao; Rodolfo Ghirlando; Carlos Alfonso; Fumio Arisaka; Ilan Attali; David L. Bain; Marina Bakhtina; Donald F. Becker; Gregory J. Bedwell; Ahmet Bekdemir; ...
    Publisher: HAL CCSD
    Project: NIH | Bacterial Expression Core (5P50GM082545-02), NIH | The chaperone function of... (5F31GM105363-02), NIH | Structure and Relations o... (5R01GM015792-39), NIH | COBRE on Membrane Protein... (5P30GM103519-04), NIH | MOLECULAR INTERACTION IN ... (2R01GM029158-19), NIH | REGULATION OF UBIQUITINAT... (5R01GM109102-04), NIH | SPECIFICITY OF INTERCALAT... (5R01CA035635-13), NIH | Structure and Function of... (3R01GM067777-07S1), NIH | Mechanisms for Histone H2... (5R01GM095822-08)

    Peer reviewed

    Add to ORCIDorcid
  • publication . Article . 2019
    Open Access English
    Authors:
    Alessandro Pagliuso; To Nam Tham; Eric Allemand; Stevens Robertin; Bruno Dupuy; Quentin Bertrand; Christophe Bécavin; Mikael Koutero; Valérie Najburg; Marie-Anne Nahori; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | BacCellEpi (670823), ANR | CBH-EUR-GS (ANR-17-EURE-0003)

    Summary RNA-binding proteins (RBPs) perform key cellular activities by controlling the function of bound RNAs. The widely held assumption that RBPs are strictly intracellular has been challenged by the discovery of secreted RBPs. However, extracellular RBPs have been de...

    Add to ORCIDorcid
  • publication . Article . Other literature type . 2012
    Open Access English
    Authors:
    Jean-Marie Bourhis; Natacha Mariano; Yuguang Zhao; Karl Harlos; Jean-Yves Exposito; E Y Jones; Catherine Moali; Nushin Aghajari; David J.S. Hulmes;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: WT

    Numerous, often lethal, genetic disorders of bone, cartilage, blood vessels and skin have been linked to defects in the assembly of collagens1. In humans, among the 28 different genetic types of collagen2, those that form the banded fibrils seen in tissues (types I, II,...

    Add to ORCIDorcid
  • publication . Article . 2018
    Open Access English
    Authors:
    Laura Medve; Silvia Achilli; Sonia Serna; Fabio Zuccotto; Norbert Varga; Michel Thépaut; Monica Civera; Corinne Vivès; Franck Fieschi; Niels Reichardt; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | IMMUNOSHAPE (642870)

    A library of mannose‐ and fucose‐based glycomimetics was synthesized and screened in a microarray format against a set of C‐type lectin receptors (CLRs) that included DC‐SIGN, DC‐SIGNR, langerin, and dectin‐2. Glycomimetic ligands able to interact with dectin‐2 were ide...

    Add to ORCIDorcid
99 research outcomes, page 1 of 10