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8 research outcomes, page 1 of 1
  • publication . Article . 2016
    Open Access
    Authors:
    Michele Chiappi; José Javier Conesa; Eva Pereiro; Carlos Oscar S. Sorzano; María Josefa Rodríguez; Katja Henzler; Gerd Schneider; Francisco Javier Chichón; José L. Carrascosa;
    Persistent Identifiers
    Project: EC | MULTIFUN (262943), EC | BIOSTRUCT-X (283570)

    Background Recent advances in nanoparticle design have generated new possibilities for nano-biotechnology and nano-medicine. Here we used cryo-soft X-ray tomography (cryo-SXT) to collect comprehensive three-dimensional (3D) data to characterise the interaction of superp...

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  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    Blas Moreno-Beltrán; Alejandra Guerra-Castellano; Antonio Díaz-Quintana; Rebecca Del Conte; Sofía M. García-Mauriño; Sofía Díaz-Moreno; Katiuska González-Arzola; Carlos Santos-Ocaña; Adrián Velázquez-Campoy; Miguel A. De la Rosa; ...
    Persistent Identifiers
    Project: EC | CALIPSO (312284), EC | BIO-NMR (261863)

    Peer reviewed

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  • publication . Article . 2018
    Open Access English
    Authors:
    Laura Medve; Silvia Achilli; Sonia Serna; Fabio Zuccotto; Norbert Varga; Michel Thépaut; Monica Civera; Corinne Vivès; Franck Fieschi; Niels Reichardt; ...
    Persistent Identifiers
    Publisher: Wiley
    Project: EC | IMMUNOSHAPE (642870)

    A library of mannose‐ and fucose‐based glycomimetics was synthesized and screened in a microarray format against a set of C‐type lectin receptors (CLRs) that included DC‐SIGN, DC‐SIGNR, langerin, and dectin‐2. Glycomimetic ligands able to interact with dectin‐2 were ide...

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  • publication . Article . 2016
    Open Access
    Authors:
    Simon Jupp; James Malone; Tony Burdett; Jean-Karim Hériché; Eleanor Williams; Jan Ellenberg; Helen Parkinson; Gabriella Rustici;
    Persistent Identifiers
    Project: EC | BIOMEDBRIDGES (284209), WT , EC | SYSTEMS MICROSCOPY (258068), UKRI | Building a Next Generatio... (BB/M018423/1)

    Background: Phenotypic data derived from high content screening is currently annotated using free-text, thus preventing the integration of independent datasets, including those generated in different biological domains, such as cell lines, mouse and human tissues.Descri...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Victor J. Somovilla; Iris A. Bermejo; Inês S. Albuquerque; Nuria Martinez-Saez; Jorge Castro-López; Fayna Garcia-Martin; Ismael Compañón; Hiroshi Hinou; Shin-Ichiro Nishimura; Jesús Jiménez-Barbero; ...
    Project: EC | SIMICA (852985), EC | BIOSTRUCT-X (283570)

    We thank the Ministerio de Economía y Competitividad (projects CTQ2015-67727-R, UNLR13-4E-1931, CTQ2013-44367-C2-2-P, CTQ2015-64597-C2-1P, and BFU2016-75633-P). I. A. B. thanks the Asociación Española Contra el Cancer en La Rioja for a grant. I. S. A. and G. J. L. B. th...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Sirarat Sarntivijai; Drashtti Vasant; Simon Jupp; Gary Saunders; A. Patrícia Bento; Daniel Gonzalez; Joanna Betts; Samiul Hasan; Gautier Koscielny; Ian Dunham; ...
    Persistent Identifiers
    Publisher: Springer Nature
    Project: EC | BIOMEDBRIDGES (284209), WT

    Background The Centre for Therapeutic Target Validation (CTTV - https://www.targetvalidation.org/) was established to generate therapeutic target evidence from genome-scale experiments and analyses. CTTV aims to support the validity of therapeutic targets by integrating...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Ismael Compañón; Ana Guerreiro; Vincenzo Mangini; Jorge Castro-López; Margarita Escudero-Casao; Alberto Avenoza; Jesús H. Busto; Sergio Castillón; Jesús Jiménez-Barbero; Juan Luis Asensio; ...
    Project: EC | TagIt (676832), EC | ProteinConjugates (675007), EC | BIOSTRUCT-X (283570)

    GalNAc-glycopeptides derived from mucin MUC1 are an important class of tumor-associated antigens. α-O-glycosylation forces the peptide to adopt an extended conformation in solution, which is far from the structure observed in complexes with a model anti-MUC1 antibody. H...

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  • publication . Article . 2016
    Open Access
    Authors:
    Simon Jupp; Tony Burdett; Danielle Welter; Sirarat Sarntivijai; Helen Parkinson; James Malone;
    Persistent Identifiers
    Project: WT , NIH | Core 5 (2U54HG004028-06), EC | CORBEL (654248)

    Background: Authoring bio-ontologies is a task that has traditionally been undertaken by skilled experts trained in understanding complex languages such as the Web Ontology Language (OWL), in tools designed for such experts. As requests for new terms are made, the need ...

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8 research outcomes, page 1 of 1